Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND SRC, c-SRC, 6714, ENSG00000197122, P12931, ASV, p60-Src, SRC1, c-src AND Treatment
200 results:

  • 1. Allosteric SHP2 inhibition enhances regorafenib's effectiveness in colorectal cancer treatment.
    Han X; Wang W; Wang R; Zhang W; Zhu L; Xu Q; Guo W; Gu Y
    Biochem Biophys Res Commun; 2024 May; 709():149812. PubMed ID: 38564942
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Regulation of metastatic potential by drug repurposing and mitochondrial targeting in colorectal cancer cells.
    Mathur S; Srivastava P; Srivastava A; Rai NK; Abbas S; Kumar A; Tiwari M; Sharma LK
    BMC Cancer; 2024 Mar; 24(1):323. PubMed ID: 38459456
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeting isoforms of RON kinase (MST1R) drives antitumor efficacy.
    Kim J; Koh DI; Lee M; Park YS; Hong SW; Shin JS; Lee MS; Kim MH; Lee JH; Jeong J; Bae S; Hong JK; Jeong HR; Ryu YS; Kim SM; Choi M; Kim H; Ryu H; Hur SC; Park J; Hur DY; Jin DH
    Cell Death Differ; 2023 Dec; 30(12):2491-2507. PubMed ID: 37926711
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Understanding apoptotic induction by Sargentodoxa cuneata-Patrinia villosa herb pair via PI3K/AKT/mTOR signalling in colorectal cancer cells using network pharmacology and cellular studies.
    Mu BX; Li Y; Ye N; Liu S; Zou X; Qian J; Wu C; Zhuang Y; Chen M; Zhou JY
    J Ethnopharmacol; 2024 Jan; 319(Pt 3):117342. PubMed ID: 37879505
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Network pharmacology-based anti-colorectal cancer activity of piperlonguminine in the ethanolic root extract of Piper longum L.
    Singh I; Das R; Kumar A
    Med Oncol; 2023 Oct; 40(11):320. PubMed ID: 37796360
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.
    Beekhof R; Bertotti A; Böttger F; Vurchio V; Cottino F; Zanella ER; Migliardi G; Viviani M; Grassi E; Lupo B; Henneman AA; Knol JC; Pham TV; de Goeij-de Haas R; Piersma SR; Labots M; Verheul HMW; Trusolino L; Jimenez CR
    Sci Transl Med; 2023 Aug; 15(709):eabm3687. PubMed ID: 37585503
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. SKAP1 Is a Novel Biomarker and Therapeutic Target for Gastric cancer: Evidence from Expression, Functional, and Bioinformatic Analyses.
    Zhu L; Yu Q; Li Y; Zhang M; Peng Z; Wang S; Quan Z; Gao D
    Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511629
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Expression of ALCAM in Clinical Colon cancer and Relationship With Patients' treatment Responses.
    Fang Z; Zeng JJ; Yang Y; Ruge F; Lane J; Hargest R; Jiang WG
    In Vivo; 2023; 37(3):1117-1128. PubMed ID: 37103072
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. src-FAK Signaling Mediates Interleukin 6-Induced HCT116 colorectal cancer Epithelial-Mesenchymal Transition.
    Huang YH; Chen HK; Hsu YF; Chen HC; Chuang CH; Huang SW; Hsu MJ
    Int J Mol Sci; 2023 Apr; 24(7):. PubMed ID: 37047623
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. PRPF19 facilitates colorectal cancer liver metastasis through activation of the src-YAP1 pathway via K63-linked ubiquitination of MYL9.
    Zhou R; Chen J; Xu Y; Ye Y; Zhong G; Chen T; Qiu L
    Cell Death Dis; 2023 Apr; 14(4):258. PubMed ID: 37031206
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Combining MEK and src inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo.
    Fan F; Ghosh S; Powell R; Roszik J; Park Y; Sobieski M; Sorokin A; Stephan C; Kopetz S; Ellis LM; Bhattacharya R
    PLoS One; 2023; 18(3):e0281063. PubMed ID: 36952536
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. A reversible src-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF
    Ruiz-Saenz A; Atreya CE; Wang C; Pan B; Dreyer CA; Brunen D; Prahallad A; Muñoz DP; Ramms DJ; Burghi V; Spassov DS; Fewings E; Hwang YC; Cowdrey C; Moelders C; Schwarzer C; Wolf DM; Hann B; VandenBerg SR; Shokat K; Moasser MM; Bernards R; Gutkind JS; van 't Veer LJ; Coppé JP
    Nat Cancer; 2023 Feb; 4(2):240-256. PubMed ID: 36759733
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis.
    Fatima I; Uppada JP; Chhonker YS; Gowrikumar S; Barman S; Roy S; Tolentino KT; Palermo N; Natarajan A; Beauchamp DR; Vecchio A; Murry DJ; Singh AB; Hopkins CR; Dhawan P
    Biomed Pharmacother; 2023 Mar; 159():114255. PubMed ID: 36696800
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. SHP2 deneddylation mediates tumor immunosuppression in colon cancer via the CD47/SIRPα axis.
    Li Y; Zhou H; Liu P; Lv D; Shi Y; Tang B; Xu J; Zhong T; Xu W; Zhang J; Zhou J; Ying K; Zhao Y; Sun Y; Jiang Z; Cheng H; Zhang X; Ke Y
    J Clin Invest; 2023 Feb; 133(4):. PubMed ID: 36626230
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Anti-cancer Effects of a New Herbal Medicine PSY by Inhibiting the STAT3 Signaling Pathway in colorectal cancer Cells and Its Phytochemical Analysis.
    Han S; Kim H; Lee MY; Lee J; Ahn KS; Ha IJ; Lee SG
    Int J Mol Sci; 2022 Nov; 23(23):. PubMed ID: 36499154
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Enriching Chemical Space of Bioactive Scaffolds by New Ring Systems: Benzazocines and Their Metal Complexes as Potential Anticancer Drugs.
    Kuznetcova I; Ostojić M; Gligorijević N; Aranđelović S; Arion VB
    Inorg Chem; 2022 Dec; 61(50):20445-20460. PubMed ID: 36473464
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The potential mechanism of Neu5Gc inducing colorectal cancer based on network pharmacology and experimental validation.
    Zhang LC; Liu YN; La XQ; Yan SN; Chen Y; Liang JY; Li ZY
    Naunyn Schmiedebergs Arch Pharmacol; 2023 Apr; 396(4):705-718. PubMed ID: 36456746
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 colorectal cancer Cells.
    Wang M; Xiang Y; Wang R; Zhang L; Zhang H; Chen H; Luan X; Chen L
    Molecules; 2022 Nov; 27(22):. PubMed ID: 36431875
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Phosphorylation-mediated interaction between human E26 transcription factor 1 and specific protein 1 is required for tumor cell migration.
    Wen X; Sun X; Ou Z; Jiang J; Chen Q; He X; Hu Z; Qiao H; Zhou K; Li X; Deng Y; Wen J
    Acta Biochim Biophys Sin (Shanghai); 2022 Oct; 54(10):1441-1452. PubMed ID: 36305724
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy.
    Khan T; Lyons NJ; Gough M; Kwah KKX; Cuda TJ; Snell CE; Tse BW; Sokolowski KA; Pearce LA; Adams TE; Rose SE; Puttick S; Pajic M; Adams MN; He Y; Hooper JD; Kryza T
    Theranostics; 2022; 12(16):6915-6930. PubMed ID: 36276654
    [No Abstract]    [Full Text] [Related]  


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