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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND STAT3, FLJ20882, 6774, ENSG00000168610, APRF, P40763, MGC16063
998 results:

  • 1. Targeting CSF1R in myeloid-derived suppressor cells: insights into its immunomodulatory functions in colorectal cancer and therapeutic implications.
    Tong X; Qiao S; Dong Z; Zhao X; Du X; Niu W
    J Nanobiotechnology; 2024 Jul; 22(1):409. PubMed ID: 38992688
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer.
    Bajpai P; Agarwal S; Afaq F; Al Diffalha S; Chandrashekar DS; Kim HG; Shelton A; Miller CR; Singh SK; Singh R; Varambally S; Nagaraju GP; Manne A; Paluri R; Khushman M; Manne U
    J Exp Clin Cancer Res; 2024 Jul; 43(1):192. PubMed ID: 38992681
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and stat3 signaling regardless of KRAS or BRAF mutational status.
    Zhang J; Zhou L; Zhao S; El-Deiry WS
    Oncotarget; 2024 Jul; 15():424-438. PubMed ID: 38953895
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of novel naphthoquinothiazole derivatives as potent antitumor agents through inhibiting stat3.
    Fan D; Liu P; Li Z; He X; Zhang L; Jiang W; Ang W; Yang T
    Bioorg Chem; 2024 Sep; 150():107565. PubMed ID: 38905884
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Interleukin-6 serves as a critical factor in various cancer progression and therapy.
    Mohamed AH; Ahmed AT; Al Abdulmonem W; Bokov DO; Shafie A; Al-Hetty HRAK; Hsu CY; Alissa M; Nazir S; Jamali MC; Mudhafar M
    Med Oncol; 2024 Jun; 41(7):182. PubMed ID: 38900329
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Structural Optimization of Marine Natural Product Pretrichodermamide B for the Treatment of Colon cancer by Targeting the JAK/stat3 Signaling Pathway.
    Zhou Y; He N; Liu Q; Li R; Yang L; Kang W; Zhang X; Xu X; Yao G; Wang P; Wang CY; Yang J; Liu Z
    J Med Chem; 2024 Jul; 67(13):10783-10794. PubMed ID: 38888591
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. CLK3 positively promoted colorectal cancer proliferation by activating IL-6/stat3 signaling.
    Ma Y; Gao F; Liu Y
    Exp Cell Res; 2024 Jul; 440(1):114132. PubMed ID: 38885806
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The Glabridin from Huangqin Decoction Prevents the Development of Ulcerative Colitis into Colitis-Associated colorectal cancer by Modulating MMP1/MMP3 Activity.
    Li R; Chi H; Liao X; Cen S; Zou Y
    Int Immunopharmacol; 2024 Jun; 135():112262. PubMed ID: 38805906
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis.
    Ma Z; Sun Y; Yu Y; Xiao W; Xiao Z; Zhong T; Xiang X; Li Z
    Cell Commun Signal; 2024 May; 22(1):295. PubMed ID: 38802814
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/stat3 axis in a colorectal cancer model.
    Sun Z; Xu Y; Shao B; Dang P; Hu S; Sun H; Chen C; Wang C; Liu J; Liu Y; Hu J
    J Immunother Cancer; 2024 May; 12(5):. PubMed ID: 38782541
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. PDIA3 driven stat3/PD-1 signaling promotes M2 TAM polarization and aggravates colorectal cancer progression.
    Fan J; Wang L; Zhang C; Wu X; Han L; Zhang X; Gao S; Xue J; Zhang Q
    Aging (Albany NY); 2024 May; 16(10):8880-8897. PubMed ID: 38761176
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Exploring active ingredients and mechanisms of Coptidis Rhizoma-ginger against colon cancer using network pharmacology and molecular docking.
    Zeng T; Ling C; Liang Y
    Technol Health Care; 2024; 32(S1):523-542. PubMed ID: 38759074
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Pharmacokinetic studies, molecular docking, and molecular dynamics simulations of phytochemicals from Morus alba: a multi receptor approach for potential therapeutic agents in colorectal cancer.
    Stany B; Mishra S; Rao KVB
    Med Oncol; 2024 May; 41(6):156. PubMed ID: 38750377
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Vesicle-associated membrane protein 8 knockdown exerts anti-proliferative, pro-apoptotic, anti-autophagic, and pro-ferroptotic effects on colorectal cancer cells by inhibition of the JAK/stat3 pathway.
    Xu Y; Yang T; Xu Q; Tang Y; Yang Q
    J Bioenerg Biomembr; 2024 Aug; 56(4):419-431. PubMed ID: 38720136
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Differential expression of angiogenesis-related genes 'VEGF' and 'angiopoietin-1' in metastatic and EMAST-positive colorectal cancer patients.
    Torshizi Esfahani A; Mohammadpour S; Jalali P; Yaghoobi A; Karimpour R; Torkamani S; Pardakhtchi A; Salehi Z; Nazemalhosseini-Mojarad E
    Sci Rep; 2024 May; 14(1):10539. PubMed ID: 38719941
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. [Upregulating KLF11 ameliorates intestinal inflammation in mice with 2, 4, 6-trinitrobenesulfonic acid-induced colitis by inhibiting the JAK2/stat3 signaling pathway].
    Xi J; Zhang M; Zhang Y; Zhang C; Zhang Y; Wang R; Shen L; Li J; Song X
    Nan Fang Yi Ke Da Xue Xue Bao; 2024 Apr; 44(4):765-772. PubMed ID: 38708511
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting stat3 and elevating ROS level.
    Zhang L; Liu P; Jiang Y; Fan D; He X; Zhang J; Luo B; Sui J; Luo Y; Fu X; Yang T
    Eur J Med Chem; 2024 Jun; 272():116448. PubMed ID: 38704936
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/stat3/GPX4 axis.
    Lai JQ; Zhao LL; Hong C; Zou QM; Su JX; Li SJ; Zhou XF; Li ZS; Deng B; Cao J; Qi Q
    Acta Pharmacol Sin; 2024 Aug; 45(8):1715-1726. PubMed ID: 38684798
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. RAC1
    Shi X; Chen W; Yin Y; Cao H; Wang X; Jiang W; Li Q; Li X; Yu Y; Wang X
    Cancer Lett; 2024 Jun; 592():216909. PubMed ID: 38679407
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Upregulation of EMR1 (ADGRE1) by Tumor-Associated Macrophages Promotes Colon cancer Progression by Activating the JAK2/STAT1,3 Signaling Pathway in Tumor Cells.
    Akter R; Park R; Lee SK; Han EJ; Park KS; Park J; Cho MY
    Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673975
    [TBL] [Abstract] [Full Text] [Related]  


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