Terms: = Colorectal cancer AND STAT3, FLJ20882, 6774, ENSG00000168610, APRF, P40763, MGC16063 AND Treatment
395 results:
1. Targeting CSF1R in myeloid-derived suppressor cells: insights into its immunomodulatory functions in colorectal cancer and therapeutic implications.
Tong X; Qiao S; Dong Z; Zhao X; Du X; Niu W
J Nanobiotechnology; 2024 Jul; 22(1):409. PubMed ID: 38992688
[TBL] [Abstract] [Full Text] [Related]
2. Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer.
Bajpai P; Agarwal S; Afaq F; Al Diffalha S; Chandrashekar DS; Kim HG; Shelton A; Miller CR; Singh SK; Singh R; Varambally S; Nagaraju GP; Manne A; Paluri R; Khushman M; Manne U
J Exp Clin Cancer Res; 2024 Jul; 43(1):192. PubMed ID: 38992681
[TBL] [Abstract] [Full Text] [Related]
3. Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and stat3 signaling regardless of KRAS or BRAF mutational status.
Zhang J; Zhou L; Zhao S; El-Deiry WS
Oncotarget; 2024 Jul; 15():424-438. PubMed ID: 38953895
[TBL] [Abstract] [Full Text] [Related]
4. Design, synthesis and biological evaluation of novel naphthoquinothiazole derivatives as potent antitumor agents through inhibiting stat3.
Fan D; Liu P; Li Z; He X; Zhang L; Jiang W; Ang W; Yang T
Bioorg Chem; 2024 Sep; 150():107565. PubMed ID: 38905884
[TBL] [Abstract] [Full Text] [Related]
5. Structural Optimization of Marine Natural Product Pretrichodermamide B for the treatment of Colon cancer by Targeting the JAK/stat3 Signaling Pathway.
Zhou Y; He N; Liu Q; Li R; Yang L; Kang W; Zhang X; Xu X; Yao G; Wang P; Wang CY; Yang J; Liu Z
J Med Chem; 2024 Jul; 67(13):10783-10794. PubMed ID: 38888591
[TBL] [Abstract] [Full Text] [Related]
6. CLK3 positively promoted colorectal cancer proliferation by activating IL-6/stat3 signaling.
Ma Y; Gao F; Liu Y
Exp Cell Res; 2024 Jul; 440(1):114132. PubMed ID: 38885806
[TBL] [Abstract] [Full Text] [Related]
7. Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis.
Ma Z; Sun Y; Yu Y; Xiao W; Xiao Z; Zhong T; Xiang X; Li Z
Cell Commun Signal; 2024 May; 22(1):295. PubMed ID: 38802814
[TBL] [Abstract] [Full Text] [Related]
8. Exploring active ingredients and mechanisms of Coptidis Rhizoma-ginger against colon cancer using network pharmacology and molecular docking.
Zeng T; Ling C; Liang Y
Technol Health Care; 2024; 32(S1):523-542. PubMed ID: 38759074
[TBL] [Abstract] [Full Text] [Related]
9. Pharmacokinetic studies, molecular docking, and molecular dynamics simulations of phytochemicals from Morus alba: a multi receptor approach for potential therapeutic agents in colorectal cancer.
Stany B; Mishra S; Rao KVB
Med Oncol; 2024 May; 41(6):156. PubMed ID: 38750377
[TBL] [Abstract] [Full Text] [Related]
10. [Upregulating KLF11 ameliorates intestinal inflammation in mice with 2, 4, 6-trinitrobenesulfonic acid-induced colitis by inhibiting the JAK2/stat3 signaling pathway].
Xi J; Zhang M; Zhang Y; Zhang C; Zhang Y; Wang R; Shen L; Li J; Song X
Nan Fang Yi Ke Da Xue Xue Bao; 2024 Apr; 44(4):765-772. PubMed ID: 38708511
[TBL] [Abstract] [Full Text] [Related]
11. Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/stat3/GPX4 axis.
Lai JQ; Zhao LL; Hong C; Zou QM; Su JX; Li SJ; Zhou XF; Li ZS; Deng B; Cao J; Qi Q
Acta Pharmacol Sin; 2024 Aug; 45(8):1715-1726. PubMed ID: 38684798
[TBL] [Abstract] [Full Text] [Related]
12. Repurposing diacerein to suppress colorectal cancer growth by inhibiting the DCLK1/stat3 signaling pathway.
Ye Q; Zhu Y; Shi M; Lv L; Gong Y; Zhang L; Yang L; Zhao H; Zhao C; Xu H
Chin J Nat Med; 2024 Apr; 22(4):318-328. PubMed ID: 38658095
[TBL] [Abstract] [Full Text] [Related]
13. Arenobufagin enhances T-cell anti-tumor immunity in colorectal cancer by modulating HSP90β accessibility.
Shang Z; Fan Y; Xi S; Zhang S; Shen W; Tao L; Xu C; Tan J; Fan M; Ma H; Lai Y; Sun D; Cheng H
Phytomedicine; 2024 Jun; 128():155497. PubMed ID: 38640855
[TBL] [Abstract] [Full Text] [Related]
14. Therapeutic Effect of Proteinase-Activated Receptor-1 Antagonist on Colitis-Associated Carcinogenesis.
Li X; Kurahara LH; Zhao Z; Zhao F; Ishikawa R; Ohmichi K; Li G; Yamashita T; Hashimoto T; Hirano M; Sun Z; Hirano K
Cell Mol Gastroenterol Hepatol; 2024; 18(1):105-131. PubMed ID: 38614455
[TBL] [Abstract] [Full Text] [Related]
15. Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer.
Dmello RS; Palmieri M; Thilakasiri PS; Doughty L; Nero TL; Poh AR; To SQ; Lee EF; Douglas Fairlie W; Mielke L; Parker MW; Poon IKH; Batlle E; Ernst M; Chand AL
Cell Death Dis; 2024 Apr; 15(4):255. PubMed ID: 38600086
[TBL] [Abstract] [Full Text] [Related]
16. Mitotic Spindle Positioning (MISP) Facilitates colorectal cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the JAK2-stat3 Signaling Pathway.
Hiura K; Watanabe M; Hirose N; Nakano K; Okamura T; Sasaki H; Sasaki N
Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474305
[TBL] [Abstract] [Full Text] [Related]
17. JAK/stat3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
Pennel KAF; Hatthakarnkul P; Wood CS; Lian GY; Al-Badran SSF; Quinn JA; Legrini A; Inthagard J; Alexander PG; van Wyk H; Kurniawan A; Hashmi U; Gillespie MA; Mills M; Ammar A; Hay J; Andersen D; Nixon C; Rebus S; Chang DK; Kelly C; Harkin A; Graham J; Church D; Tomlinson I; Saunders M; Iveson T; Lannagan TRM; Jackstadt R; Maka N; Horgan PG; Roxburgh CSD; Sansom OJ; McMillan DC; Steele CW; Jamieson NB; Park JH; Roseweir AK; Edwards J
J Exp Clin Cancer Res; 2024 Mar; 43(1):64. PubMed ID: 38424636
[TBL] [Abstract] [Full Text] [Related]
18. Fusobacterium nucleatum promotes tumor progression in KRAS p.G12D-mutant colorectal cancer by binding to DHX15.
Zhu H; Li M; Bi D; Yang H; Gao Y; Song F; Zheng J; Xie R; Zhang Y; Liu H; Yan X; Kong C; Zhu Y; Xu Q; Wei Q; Qin H
Nat Commun; 2024 Feb; 15(1):1688. PubMed ID: 38402201
[TBL] [Abstract] [Full Text] [Related]
19. Kurarinone targets JAK2-stat3 signaling in colon cancer-stem-like cells.
Prajapati KS; Kumar S
Cell Biochem Funct; 2024 Mar; 42(2):e3959. PubMed ID: 38390770
[TBL] [Abstract] [Full Text] [Related]
20. Targeting stat3 Enzyme for cancer treatment.
Arun S; Patel PK; Lakshmanan K; Rajangopal K; Swaminathan G; Byran G
Mini Rev Med Chem; 2024; 24(13):1252-1261. PubMed ID: 38299278
[TBL] [Abstract] [Full Text] [Related]
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