Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND STAT3, FLJ20882, 6774, ENSG00000168610, APRF, P40763, MGC16063 AND Treatment
378 results:

  • 1. Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer.
    Dmello RS; Palmieri M; Thilakasiri PS; Doughty L; Nero TL; Poh AR; To SQ; Lee EF; Douglas Fairlie W; Mielke L; Parker MW; Poon IKH; Batlle E; Ernst M; Chand AL
    Cell Death Dis; 2024 Apr; 15(4):255. PubMed ID: 38600086
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Mitotic Spindle Positioning (MISP) Facilitates colorectal cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the JAK2-stat3 Signaling Pathway.
    Hiura K; Watanabe M; Hirose N; Nakano K; Okamura T; Sasaki H; Sasaki N
    Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474305
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. JAK/stat3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
    Pennel KAF; Hatthakarnkul P; Wood CS; Lian GY; Al-Badran SSF; Quinn JA; Legrini A; Inthagard J; Alexander PG; van Wyk H; Kurniawan A; Hashmi U; Gillespie MA; Mills M; Ammar A; Hay J; Andersen D; Nixon C; Rebus S; Chang DK; Kelly C; Harkin A; Graham J; Church D; Tomlinson I; Saunders M; Iveson T; Lannagan TRM; Jackstadt R; Maka N; Horgan PG; Roxburgh CSD; Sansom OJ; McMillan DC; Steele CW; Jamieson NB; Park JH; Roseweir AK; Edwards J
    J Exp Clin Cancer Res; 2024 Mar; 43(1):64. PubMed ID: 38424636
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Fusobacterium nucleatum promotes tumor progression in KRAS p.G12D-mutant colorectal cancer by binding to DHX15.
    Zhu H; Li M; Bi D; Yang H; Gao Y; Song F; Zheng J; Xie R; Zhang Y; Liu H; Yan X; Kong C; Zhu Y; Xu Q; Wei Q; Qin H
    Nat Commun; 2024 Feb; 15(1):1688. PubMed ID: 38402201
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Kurarinone targets JAK2-stat3 signaling in colon cancer-stem-like cells.
    Prajapati KS; Kumar S
    Cell Biochem Funct; 2024 Mar; 42(2):e3959. PubMed ID: 38390770
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Entero-toxigenic
    Yang J; Wang X; Hu T; Huang H; Chen G; Jin B; Zeng G; Liu J
    Cell Cycle; 2024 Jan; 23(1):70-82. PubMed ID: 38273425
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The expression of UNC5D is abnormal in the early stage of colorectal tumors associated with its proliferation and migration.
    Shi LP; Zou C; Mao LJ; Chen TT; Xie T
    Eur Rev Med Pharmacol Sci; 2024 Jan; 28(1):199-213. PubMed ID: 38235871
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Inhibition of CSF1R and KIT With Pexidartinib Reduces Inflammatory Signaling and Cell Viability in Endometriosis.
    Dunn TN; Cope DI; Tang S; Sirupangi T; Parks SE; Liao Z; Yuan F; Creighton CJ; Masand RP; Alpuing Radilla L; Guan X; Detti L; Monsivais D; Matzuk MM
    Endocrinology; 2024 Feb; 165(4):. PubMed ID: 38227801
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. KLF7 promotes colon adenocarcinoma progression through the PDGFB signaling pathway.
    Zhang Z; Jiang X; Li K; Qiao S; Li M; Mei Y; Ding L; Lv Q; Ding Y; Zhao Y; Lv G; Tan G; Yang H; Li G; Gao X; Liu M
    Int J Biol Sci; 2024; 20(1):387-402. PubMed ID: 38164176
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated cancer.
    Deng Y; Huang X; Chen X; Wang M; Tian L; Zhou H; Yang W; He F; Yin W
    Nutrients; 2023 Nov; 15(22):. PubMed ID: 38004214
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Role of HDAC6-stat3 in immunomodulatory pathways in colorectal cancer cells.
    Mardones C; Navarrete-Munoz C; Armijo ME; Salgado K; Rivas-Valdes F; Gonzalez-Pecchi V; Farkas C; Villagra A; Hepp MI
    Mol Immunol; 2023 Dec; 164():98-111. PubMed ID: 37992541
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Curcuminoids Modulated the IL-6/JAK/stat3 Signaling Pathway in LoVo and HT-29 colorectal cancer Cells.
    Li Q; Ding Y; Ou Y; Li M; Jithavech P; Buranasudja V; Sritularak B; Xu Y; Rojsitthisak P; Han J
    Curr Pharm Des; 2023; 29(36):2867-2876. PubMed ID: 37957863
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. P53‑microRNA interactions regulate the response of colorectal tumor cells to oxaliplatin under normoxic and hypoxic conditions.
    Zhang J; Li C; Sun L; Sun D; Zhao T
    Oncol Rep; 2023 Dec; 50(6):. PubMed ID: 37921068
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Comprehensive exploration of Biochanin A as an oncotherapeutics potential in the treatment of multivarious cancers with molecular insights.
    Sohel M
    Phytother Res; 2024 Feb; 38(2):489-506. PubMed ID: 37905329
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Elucidation of the anti-colon cancer mechanism of Phellinus baumii polyphenol by an integrative approach of network pharmacology and experimental verification.
    Liu X; Cui S; Li W; Xie H; Shi L
    Int J Biol Macromol; 2023 Dec; 253(Pt 6):127429. PubMed ID: 37838121
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. AURKA inhibitor-induced PD-L1 upregulation impairs antitumor immune responses.
    Meng B; Zhao X; Jiang S; Xu Z; Li S; Wang X; Ma W; Li L; Liu D; Zheng J; Peng H; Shi M
    Front Immunol; 2023; 14():1182601. PubMed ID: 37781397
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Deciphering the mechanism of
    Gu J; Lv X; Li W; Li G; He X; Zhang Y; Shi L; Zhang X
    Front Immunol; 2023; 14():1230681. PubMed ID: 37781363
    [No Abstract]    [Full Text] [Related]  

  • 18. Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/stat3 signaling axis through interaction with stat3.
    Wu A; Fang D; Liu Y; Shi X; Zhong Z; Zhou B; Ye L; Sun X; Jiang L
    Theranostics; 2023; 13(14):4730-4744. PubMed ID: 37771783
    [No Abstract]    [Full Text] [Related]  

  • 19. IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy.
    Pecharromán I; Solé L; Álvarez-Villanueva D; Lobo-Jarne T; Alonso-Marañón J; Bertran J; Guillén Y; Montoto Á; Martínez-Iniesta M; García-Hernández V; Giménez G; Salazar R; Santos C; Garrido M; Borràs E; Sabidó E; Bonfill-Teixidor E; Iurlaro R; Seoane J; Villanueva A; Iglesias M; Bigas A; Espinosa L
    EMBO J; 2023 Nov; 42(21):e114719. PubMed ID: 37737566
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway.
    Yang H; Zhang Y; Zhang D; Qian L; Yang T; Wu X
    Eur J Histochem; 2023 Sep; 67(3):. PubMed ID: 37700733
    [TBL] [Abstract] [Full Text] [Related]  


    of 19.