Terms: = Colorectal cancer AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS
185 results:
1. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
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2. The deubiquitinase USP10 mediates crosstalk between the lkb1/AMPK axis and Wnt/β-catenin signaling in cancer.
Wang Y; Liu J; Zheng S; Cao L; Li Y; Sheng R
FEBS Lett; 2023 Dec; 597(24):3061-3071. PubMed ID: 37873736
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3. Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
Yang SR; Gedvilaite E; Ptashkin R; Chang J; Ziegler J; Mata DA; Villafania LB; Nafa K; Hechtman JF; Benayed R; Zehir A; Benhamida J; Arcila ME; Mandelker D; Rudin CM; Paik PK; Drilon A; Schoenfeld AJ; Ladanyi M
J Thorac Oncol; 2024 Mar; 19(3):409-424. PubMed ID: 37838086
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4. Familial intestinal polyposis and device assisted enteroscopy: where do we stand?
Losurdo G; Di Leo M; Rizzi S; Lacavalla I; Celiberto F; Iannone A; Rendina M; Ierardi E; Iabichino G; De Luca L; Di Leo A
Expert Rev Gastroenterol Hepatol; 2023; 17(8):811-816. PubMed ID: 37515779
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5. Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Ai YL; Wang WJ; Liu FJ; Fang W; Chen HZ; Wu LZ; Hong X; Zhu Y; Zhang CX; Liu LY; Hong WB; Zhou B; Chen QT; Wu Q
Cell Res; 2023 Dec; 33(12):904-922. PubMed ID: 37460805
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6. Clinical Characteristics and Responses to Immune Checkpoint Inhibitors in RET-Aberrant Digestive Tract Tumours.
Yen CC; Yeh YM; Huang HY; Ting YL; Fu PA; Lin TC; Liu IT; Yen CJ
Target Oncol; 2023 Jul; 18(4):611-623. PubMed ID: 37347391
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7. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
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8. Tumor loss-of-function mutations in stk11/lkb1 induce cachexia.
Iyengar P; Gandhi AY; Granados J; Guo T; Gupta A; Yu J; Llano EM; Zhang F; Gao A; Kandathil A; Williams D; Gao B; Girard L; Malladi VS; Shelton JM; Evers BM; Hannan R; Ahn C; Minna JD; Infante RE
JCI Insight; 2023 Apr; 8(8):. PubMed ID: 37092555
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9. Survival, surveillance, and genetics in patients with Peutz-Jeghers syndrome: A nationwide study.
Jelsig AM; van Overeem Hansen T; Gede LB; Qvist N; Christensen LL; Lautrup CK; Frederiksen JH; Sunde L; Ousager LB; Ljungmann K; Bertelsen B; Karstensen JG
Clin Genet; 2023 Jul; 104(1):81-89. PubMed ID: 37017260
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10. Genetic Predisposition to colorectal cancer: How Many and Which Genes to Test?
Rebuzzi F; Ulivi P; Tedaldi G
Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768460
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11. Strong Hereditary Predispositions to colorectal cancer.
Hryhorowicz S; Kaczmarek-Ryś M; Lis-Tanaś E; Porowski J; Szuman M; Grot N; Kryszczyńska A; Paszkowski J; Banasiewicz T; Pławski A
Genes (Basel); 2022 Dec; 13(12):. PubMed ID: 36553592
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12. Rates of repeated colonoscopies to clean the colon from low-risk and high-risk adenomas: results from the EPoS trials.
Juul FE; Garborg K; Nesbakken E; Løberg M; Wieszczy P; Cubiella J; Kalager M; Kaminski MF; Erichsen R; Adami HO; Ferlitsch M; Furholm SKB; Zauber AG; Quintero E; Bugajski M; Holme Ø; Dekker E; Jover R; Bretthauer M
Gut; 2023 May; 72(5):951-957. PubMed ID: 36307178
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13. Whole Genome Sequencing Applied in Familial Hamartomatous Polyposis Identifies Novel Structural Variations.
Kariv R; Dahary D; Yaron Y; Petel-Galil Y; Malcov M; Rosner G
Genes (Basel); 2022 Aug; 13(8):. PubMed ID: 36011318
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14. PTEN and lkb1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis.
Cotton JL; Dang K; Hu L; Sun Y; Singh A; Rajurkar MS; Li Q; Wu X; Mao J
Cell Rep; 2022 Jul; 40(3):111125. PubMed ID: 35858546
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15. Diagnosis and Management of cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on colorectal cancer.
Boland CR; Idos GE; Durno C; Giardiello FM; Anderson JC; Burke CA; Dominitz JA; Gross S; Gupta S; Jacobson BC; Patel SG; Shaukat A; Syngal S; Robertson DJ
Gastroenterology; 2022 Jun; 162(7):2063-2085. PubMed ID: 35487791
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16. Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the U.S. Multi-Society Task Force on colorectal cancer.
Boland CR; Idos GE; Durno C; Giardiello FM; Anderson JC; Burke CA; Dominitz JA; Gross S; Gupta S; Jacobson BC; Patel SG; Shaukat A; Syngal S; Robertson DJ
Gastrointest Endosc; 2022 Jun; 95(6):1025-1047. PubMed ID: 35487765
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17. Diagnosis and Management of cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on colorectal cancer.
Boland CR; Idos GE; Durno C; Giardiello FM; Anderson JC; Burke CA; Dominitz JA; Gross S; Gupta S; Jacobson BC; Patel SG; Shaukat A; Syngal S; Robertson DJ
Am J Gastroenterol; 2022 Jun; 117(6):846-864. PubMed ID: 35471415
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18. Landscape of
Salem ME; El-Refai SM; Sha W; Puccini A; Grothey A; George TJ; Hwang JJ; O'Neil B; Barrett AS; Kadakia KC; Musselwhite LW; Raghavan D; Van Cutsem E; Tabernero J; Tie J
JCO Precis Oncol; 2022 Mar; 6():e2100245. PubMed ID: 35319967
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19. Pancreatic cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation.
Vietri MT; D'Elia G; Caliendo G; Albanese L; Signoriello G; Napoli C; Molinari AM
Genes (Basel); 2022 Feb; 13(2):. PubMed ID: 35205366
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20. Germline variant testing in serrated polyposis syndrome.
Murphy A; Solomons J; Risby P; Gabriel J; Bedenham T; Johnson M; Atkinson N; Bailey AA; Bird-Lieberman E; Leedham SJ; East JE; Biswas S
J Gastroenterol Hepatol; 2022 May; 37(5):861-869. PubMed ID: 35128723
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