Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND TCF7L2, ENSG00000148737, 6934, TCF-4 AND Treatment
49 results:

  • 1. MiR-27a-3p exacerbates cell migration and invasion in right-sided/left-sided colorectal cancer by targeting TGFBR2/tcf7l2.
    Bi L; Zhou Y; Zhang Y; Zhang X
    Cell Mol Biol (Noisy-le-grand); 2024 Jan; 70(1):148-154. PubMed ID: 38372101
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of tcf7l2.
    Duan B; Zhou X; Zhang X; Qiu F; Zhang S; Chen Y; Yang J; Wang J; Tan W
    Biochem Pharmacol; 2023 Dec; 218():115877. PubMed ID: 37879498
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Circulating Tumor DNA Dynamics and treatment Outcome of Regorafenib in Metastatic colorectal cancer.
    Lee DW; Lim Y; Kim HP; Kim SY; Roh H; Kang JK; Lee KH; Kim MJ; Ryoo SB; Park JW; Jeong SY; Park KJ; Kang GH; Han SW; Kim TY
    Cancer Res Treat; 2023 Jul; 55(3):927-938. PubMed ID: 36915247
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Comprehensive genetic characterization of rectal cancer in a large cohort of Japanese patients: differences according to tumor location.
    Hino H; Shiomi A; Hatakeyama K; Kagawa H; Manabe S; Yamaoka Y; Nagashima T; Ohshima K; Urakami K; Akiyama Y; Yamaguchi K
    J Gastroenterol; 2022 Jul; 57(7):476-485. PubMed ID: 35449312
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Characterization of genomic alterations in Chinese colorectal cancer patients.
    Huang W; Li H; Shi X; Lin M; Liao C; Zhang S; Shi W; Zhang L; Zhang X; Gan J
    Jpn J Clin Oncol; 2021 Jan; 51(1):120-129. PubMed ID: 33106877
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Andrographis-mediated chemosensitization through activation of ferroptosis and suppression of β-catenin/Wnt-signaling pathways in colorectal cancer.
    Sharma P; Shimura T; Banwait JK; Goel A
    Carcinogenesis; 2020 Oct; 41(10):1385-1394. PubMed ID: 32835374
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular characterization of colorectal cancer using whole-exome sequencing in a Taiwanese population.
    Chang YS; Lee CC; Ke TW; Chang CM; Chao DS; Huang HY; Chang JG
    Cancer Med; 2019 Jul; 8(8):3738-3747. PubMed ID: 31127692
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. miR-139-5p reverses stemness maintenance and metastasis of colon cancer stem-like cells by targeting E2-2.
    Ma X; Liu J; Li J; Li Y; Le VM; Li S; Liang X; Liu L; Liu J
    J Cell Physiol; 2019 Dec; 234(12):22703-22718. PubMed ID: 31120140
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Wnt Signalling-Targeted Therapy in the CMS2 Tumour Subtype: A New Paradigm in CRC treatment?
    Albuquerque C; Pebre Pereira L
    Adv Exp Med Biol; 2018; 1110():75-100. PubMed ID: 30623367
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Chemoradiotherapy Resistance in colorectal cancer Cells is Mediated by Wnt/β-catenin Signaling.
    Emons G; Spitzner M; Reineke S; Möller J; Auslander N; Kramer F; Hu Y; Beissbarth T; Wolff HA; Rave-Fränk M; Heßmann E; Gaedcke J; Ghadimi BM; Johnsen SA; Ried T; Grade M
    Mol Cancer Res; 2017 Nov; 15(11):1481-1490. PubMed ID: 28811361
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon cancer Cells.
    Hsu HH; Lin YM; Shen CY; Shibu MA; Li SY; Chang SH; Lin CC; Chen RJ; Viswanadha VP; Shih HN; Huang CY
    Int J Mol Sci; 2017 May; 18(6):. PubMed ID: 28587064
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation.
    Hsu HH; Chen MC; Day CH; Lin YM; Li SY; Tu CC; Padma VV; Shih HN; Kuo WW; Huang CY
    World J Gastroenterol; 2017 Feb; 23(7):1171-1179. PubMed ID: 28275297
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Wnt-β-catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer.
    Kobayashi M; Funayama R; Ohnuma S; Unno M; Nakayama K
    Cancer Sci; 2016 Dec; 107(12):1776-1784. PubMed ID: 27709738
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Target β-catenin/CD44/Nanog axis in colon cancer cells by certain N'-(2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazides.
    Radwan AA; Al-Mohanna F; Alanazi FK; Manogaran PS; Al-Dhfyan A
    Bioorg Med Chem Lett; 2016 Apr; 26(7):1664-70. PubMed ID: 26944615
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells.
    Patel J; Baranwal S; Love IM; Patel NJ; Grossman SR; Patel BB
    Cell Cycle; 2014; 13(22):3506-18. PubMed ID: 25483087
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. CD44 functions in Wnt signaling by regulating LRP6 localization and activation.
    Schmitt M; Metzger M; Gradl D; Davidson G; Orian-Rousseau V
    Cell Death Differ; 2015 Apr; 22(4):677-89. PubMed ID: 25301071
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620.
    Pooja T; Karunagaran D
    Eur J Pharmacol; 2014 Nov; 742():55-64. PubMed ID: 25205133
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Histone deacetylase inhibitors induce attenuation of Wnt signaling and tcf7l2 depletion in colorectal carcinoma cells.
    Götze S; Coersmeyer M; Müller O; Sievers S
    Int J Oncol; 2014 Oct; 45(4):1715-23. PubMed ID: 25050608
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer.
    Shanmugam V; Ramanathan RK; Lavender NA; Sinari S; Chadha M; Liang WS; Kurdoglu A; Izatt T; Christoforides A; Benson H; Phillips L; Baker A; Murray C; Hostetter G; Von Hoff DD; Craig DW; Carpten JD
    BMC Med Genomics; 2014 Jun; 7():36. PubMed ID: 24943349
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. MiR-29b downregulates canonical Wnt signaling by suppressing coactivators of β-catenin in human colorectal cancer cells.
    Subramanian M; Rao SR; Thacker P; Chatterjee S; Karunagaran D
    J Cell Biochem; 2014 Nov; 115(11):1974-84. PubMed ID: 24913975
    [TBL] [Abstract] [Full Text] [Related]  


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