Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Colorectal cancer AND TOP2A, TOP2, TP2A AND Treatment
21 results:

  • 1. Identification of potential key genes for colorectal cancer based on bioinformatics analysis.
    Li C; Cao S; Guo M; Guo A; Sun X
    Medicine (Baltimore); 2023 Dec; 102(51):e36615. PubMed ID: 38134110
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Therapeutic targeting of the TPX2/TTK network in colorectal cancer.
    Shaath H; Vishnubalaji R; Elango R; Velayutham D; Jithesh PV; Alajez NM
    Cell Commun Signal; 2023 Sep; 21(1):265. PubMed ID: 37770979
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. [Risk factors for cancer-related cognitive impairment in breast and colorectal cancer patients who undergo chemotherapy].
    Iranzo P; Callejo A; Arbej J; Menao S; Isla D; Andrés R
    An Sist Sanit Navar; 2023 Aug; 46(2):. PubMed ID: 37594060
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Network pharmacology and metabolomics elucidate the underlying mechanisms of Venenum Bufonis in the treatment of colorectal cancer.
    Tao C; Wang J; Gu Z; Ni H; Luo Y; Ling J; Chen Y; Wu Y; Liu X; Zhou Y; Xu T
    J Ethnopharmacol; 2023 Dec; 317():116695. PubMed ID: 37315651
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Chalcone Derivative CX258 Suppresses colorectal cancer via Inhibiting the top2a/Wnt/β-Catenin Signaling.
    Chen X; Lv X; Gao L; Liu J; Wang W; Guo L; Frasinyuk MS; Zhang W; Watt DS; Liu C; Liu X
    Cells; 2023 Mar; 12(7):. PubMed ID: 37048139
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Identification of a five genes prognosis signature for triple-negative breast cancer using multi-omics methods and bioinformatics analysis.
    Ma J; Chen C; Liu S; Ji J; Wu D; Huang P; Wei D; Fan Z; Ren L
    Cancer Gene Ther; 2022 Nov; 29(11):1578-1589. PubMed ID: 35474355
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. [Screening of differentially expressed genes for colorectal cancer and prediction of potential traditional Chinese medicine: based on bioinformatics].
    Yun ZJ; Wang HJ; Yu YX; Sun ZY; Yao SK
    Zhongguo Zhong Yao Za Zhi; 2022 Mar; 47(6):1666-1676. PubMed ID: 35347966
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integration of transcriptomics and metabolomics reveals anlotinib-induced cytotoxicity in colon cancer cells.
    Jia Z; Zhang Z; Tian Q; Wu H; Xie Y; Li A; Zhang H; Yang Z; Zhang X
    Gene; 2021 Jun; 786():145625. PubMed ID: 33798683
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A data-driven approach to a chemotherapy recommendation model based on deep learning for patients with colorectal cancer in Korea.
    Park JH; Baek JH; Sym SJ; Lee KY; Lee Y
    BMC Med Inform Decis Mak; 2020 Sep; 20(1):241. PubMed ID: 32962726
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The Indenoisoquinoline LMP517: A Novel Antitumor Agent Targeting both TOP1 and top2.
    Marzi L; Sun Y; Huang SN; James A; Difilippantonio S; Pommier Y
    Mol Cancer Ther; 2020 Aug; 19(8):1589-1597. PubMed ID: 32430490
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for colorectal cancer.
    Abraham AD; Esquer H; Zhou Q; Tomlinson N; Hamill BD; Abbott JM; Li L; Pike LA; Rinaldetti S; Ramirez DA; Lunghofer PJ; Gomez JD; Schaack J; Nemkov T; D'Alessandro A; Hansen KC; Gustafson DL; Messersmith WA; LaBarbera DV
    J Med Chem; 2019 Nov; 62(22):10182-10203. PubMed ID: 31675229
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Targeted multiplex proteomics for molecular prescreening and biomarker discovery in metastatic colorectal cancer.
    Serna G; Ruiz-Pace F; Cecchi F; Fasani R; Jimenez J; Thyparambil S; Landolfi S; Elez E; Vivancos A; Hembrough T; Tabernero J; Dienstmann R; Nuciforo P
    Sci Rep; 2019 Sep; 9(1):13568. PubMed ID: 31537838
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The identification of a common different gene expression signature in patients with colorectal cancer.
    Zhao ZW; Fan XX; Yang LL; Song JJ; Fang SJ; Tu JF; Chen MJ; Zheng LY; Wu FZ; Zhang DK; Ying XH; Ji JS
    Math Biosci Eng; 2019 Apr; 16(4):2942-2958. PubMed ID: 31137244
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Topoisomerase expression and amplification in solid tumours: Analysis of 24,262 patients.
    Heestand GM; Schwaederle M; Gatalica Z; Arguello D; Kurzrock R
    Eur J Cancer; 2017 Sep; 83():80-87. PubMed ID: 28728050
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations.
    Jensen NF; Agama K; Roy A; Smith DH; Pfister TD; Rømer MU; Zhang HL; Doroshow JH; Knudsen BR; Stenvang J; Brünner N; Pommier Y
    J Exp Clin Cancer Res; 2016 Mar; 35():56. PubMed ID: 27029323
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and top2a gene amplification.
    Tarpgaard LS; Qvortrup C; Nygård SB; Nielsen SL; Andersen DR; Jensen NF; Stenvang J; Detlefsen S; Brünner N; Pfeiffer P
    BMC Cancer; 2016 Feb; 16():91. PubMed ID: 26867764
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.
    Sønderstrup IM; Nygård SB; Poulsen TS; Linnemann D; Stenvang J; Nielsen HJ; Bartek J; Brünner N; Nørgaard P; Riis L
    Mol Oncol; 2015 Jun; 9(6):1207-17. PubMed ID: 25777966
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents.
    Zoppoli G; Regairaz M; Leo E; Reinhold WC; Varma S; Ballestrero A; Doroshow JH; Pommier Y
    Proc Natl Acad Sci U S A; 2012 Sep; 109(37):15030-5. PubMed ID: 22927417
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway.
    Toh YM; Li TK
    Clin Cancer Res; 2011 Aug; 17(15):5026-37. PubMed ID: 21653687
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. [Expression of topoisomerase II alpha in human colorectal carcinoma and its significance].
    Yang FD; Jia ZL
    Nan Fang Yi Ke Da Xue Xue Bao; 2010 Aug; 30(8):1959-61, 1964. PubMed ID: 20813715
    [TBL] [Abstract] [Full Text] [Related]  


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