Terms: = Colorectal cancer AND VHL, HRCA1, P40337, 7428, ENSG00000134086, RCA1, VHL1
68 results:
1. Discovery of a Meisoindigo-Derived PROTAC as the ATM Degrader: Revolutionizing colorectal cancer Therapy via Synthetic Lethality with ATR Inhibitors.
Liu TT; Wang Q; Zhou Y; Ye B; Liu T; Yan L; Fan J; Xu J; Zhou Y; Xia Z; Deng X
J Med Chem; 2024 May; 67(9):7620-7634. PubMed ID: 38634707
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2. MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells.
Zheng M; Tian S; Zhou X; Yan M; Zhou M; Yu Y; Zhang Y; Wang X; Li N; Ren L; Zhang S
Oncol Rep; 2024 May; 51(5):. PubMed ID: 38456491
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3. Pathway-driven analysis of synthetic lethal interactions in cancer using perturbation screens.
Karimpour M; Totonchi M; Behmanesh M; Montazeri H
Life Sci Alliance; 2024 Jan; 7(1):. PubMed ID: 37863651
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4. USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.
Mu M; Zhang Q; Li J; Zhao C; Li X; Chen Z; Sun X; Yu J
Cell Death Differ; 2023 Nov; 30(11):2393-2407. PubMed ID: 37816999
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5. Faecal Microbiota Transplantation [FMT] in the Treatment of Chronic Refractory Pouchitis: A Systematic Review and Meta-analysis.
Zaman S; Akingboye A; Mohamedahmed AYY; Peterknecht E; Bhattacharya P; El-Asrag ME; Iqbal TH; Quraishi MN; Beggs AD
J Crohns Colitis; 2024 Jan; 18(1):144-161. PubMed ID: 37450947
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6. Personalized Systemic Therapies in Hereditary cancer Syndromes.
Mastrodomenico L; Piombino C; Riccò B; Barbieri E; Venturelli M; Piacentini F; Dominici M; Cortesi L; Toss A
Genes (Basel); 2023 Mar; 14(3):. PubMed ID: 36980956
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7. A reciprocal feedback between colon cancer cells and Schwann cells promotes the proliferation and metastasis of colon cancer.
Han S; Wang D; Huang Y; Zeng Z; Xu P; Xiong H; Ke Z; Zhang Y; Hu Y; Wang F; Wang J; Zhao Y; Zhuo W; Zhao G
J Exp Clin Cancer Res; 2022 Dec; 41(1):348. PubMed ID: 36522730
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8. Design and characterization of PROTAC degraders specific to protein N-terminal methyltransferase 1.
Zhou Q; Wu W; Jia K; Qi G; Sun XS; Li P
Eur J Med Chem; 2022 Dec; 244():114830. PubMed ID: 36228414
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9. Tumor-to-tumor metastasis of colon cancer metastasizing to a pancreatic neuroendocrine tumor associated with von Hippel-Lindau disease: a case report.
Natsui H; Kohisa J; Yoshikawa S; Takeuchi M; Yagi R; Minagawa M; Tani T; Usuda H; Terai S
Clin J Gastroenterol; 2022 Dec; 15(6):1173-1178. PubMed ID: 35951216
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10. Patients deriving long-term benefit from immune checkpoint inhibitors demonstrate conserved patterns of site-specific mutations.
Principe DR
Sci Rep; 2022 Jul; 12(1):11490. PubMed ID: 35798829
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11. HypoxaMIRs: Key Regulators of Hallmarks of colorectal cancer.
Coronel-Hernández J; Delgado-Waldo I; Cantú de León D; López-Camarillo C; Jacobo-Herrera N; Ramos-Payán R; Pérez-Plasencia C
Cells; 2022 Jun; 11(12):. PubMed ID: 35741024
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12. A Positive Feedback Loop between Inactive vhl-Triggered Histone Lactylation and PDGFRβ Signaling Drives Clear Cell Renal Cell Carcinoma Progression.
Yang J; Luo L; Zhao C; Li X; Wang Z; Zeng Z; Yang X; Zheng X; Jie H; Kang L; Li S; Liu S; Zhou C; Liu H
Int J Biol Sci; 2022; 18(8):3470-3483. PubMed ID: 35637958
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13. Clinical considerations for the design of PROTACs in cancer.
Nieto-Jiménez C; Morafraile EC; Alonso-Moreno C; Ocaña A
Mol Cancer; 2022 Mar; 21(1):67. PubMed ID: 35249548
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14. Anti-cancer efficacy including Rb-deficient tumors and vhl-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90.
Zhao S; Zhou L; Dicker DT; Lev A; Zhang S; Ross E; El-Deiry WS
Sci Rep; 2021 Oct; 11(1):20871. PubMed ID: 34686682
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15. Physical Exercise and Quality of Life of Patients Diagnosed with colorectal cancer: Systematic Literature Review.
da Silva Bezerra KH; de Oliveira MVL; do Nascimento IJB; de Barros Rocha L; de Souza Filho LEC; Rocha RSB; da Silva ML; da Costa Cunha K
J Gastrointest Cancer; 2021 Mar; 52(1):17-22. PubMed ID: 32901444
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16. Identification of functional compounds in baru (Dipteryx alata Vog.) nuts: Nutritional value, volatile and phenolic composition, antioxidant activity and antiproliferative effect.
Oliveira-Alves SC; Pereira RS; Pereira AB; Ferreira A; Mecha E; Silva AB; Serra AT; Bronze MR
Food Res Int; 2020 May; 131():109026. PubMed ID: 32247467
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17. Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF-1α Mediated cancer Cell Viability and Vascularization.
Ratnayake R; Gunasekera SP; Ma JJ; Dang LH; Carney TJ; Paul VJ; Luesch H
Chembiochem; 2020 Aug; 21(16):2356-2366. PubMed ID: 32237262
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18. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader.
Wei J; Hu J; Wang L; Xie L; Jin MS; Chen X; Liu J; Jin J
J Med Chem; 2019 Dec; 62(23):10897-10911. PubMed ID: 31730343
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19. Targeted next-generation sequencing of well-differentiated rectal, gastric, and appendiceal neuroendocrine tumors to identify potential targets.
Park HY; Kwon MJ; Kang HS; Kim YJ; Kim NY; Kim MJ; Min KW; Choi KC; Nam ES; Cho SJ; Park HR; Min SK; Seo J; Choe JY; Lee HK
Hum Pathol; 2019 May; 87():83-94. PubMed ID: 30851333
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20. HIF-1α-induced miR-23a∼27a∼24 cluster promotes colorectal cancer progression via reprogramming metabolism.
Jin F; Yang R; Wei Y; Wang D; Zhu Y; Wang X; Lu Y; Wang Y; Zen K; Li L
Cancer Lett; 2019 Jan; 440-441():211-222. PubMed ID: 30393198
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