Terms: = Colorectal cancer AND VHL, HRCA1, P40337, 7428, ENSG00000134086, RCA1, VHL1 AND Treatment
16 results:
1. Discovery of a Meisoindigo-Derived PROTAC as the ATM Degrader: Revolutionizing colorectal cancer Therapy via Synthetic Lethality with ATR Inhibitors.
Liu TT; Wang Q; Zhou Y; Ye B; Liu T; Yan L; Fan J; Xu J; Zhou Y; Xia Z; Deng X
J Med Chem; 2024 May; 67(9):7620-7634. PubMed ID: 38634707
[TBL] [Abstract] [Full Text] [Related]
2. MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells.
Zheng M; Tian S; Zhou X; Yan M; Zhou M; Yu Y; Zhang Y; Wang X; Li N; Ren L; Zhang S
Oncol Rep; 2024 May; 51(5):. PubMed ID: 38456491
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3. Faecal Microbiota Transplantation [FMT] in the treatment of Chronic Refractory Pouchitis: A Systematic Review and Meta-analysis.
Zaman S; Akingboye A; Mohamedahmed AYY; Peterknecht E; Bhattacharya P; El-Asrag ME; Iqbal TH; Quraishi MN; Beggs AD
J Crohns Colitis; 2024 Jan; 18(1):144-161. PubMed ID: 37450947
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4. Personalized Systemic Therapies in Hereditary cancer Syndromes.
Mastrodomenico L; Piombino C; Riccò B; Barbieri E; Venturelli M; Piacentini F; Dominici M; Cortesi L; Toss A
Genes (Basel); 2023 Mar; 14(3):. PubMed ID: 36980956
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5. A reciprocal feedback between colon cancer cells and Schwann cells promotes the proliferation and metastasis of colon cancer.
Han S; Wang D; Huang Y; Zeng Z; Xu P; Xiong H; Ke Z; Zhang Y; Hu Y; Wang F; Wang J; Zhao Y; Zhuo W; Zhao G
J Exp Clin Cancer Res; 2022 Dec; 41(1):348. PubMed ID: 36522730
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6. Patients deriving long-term benefit from immune checkpoint inhibitors demonstrate conserved patterns of site-specific mutations.
Principe DR
Sci Rep; 2022 Jul; 12(1):11490. PubMed ID: 35798829
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7. Physical Exercise and Quality of Life of Patients Diagnosed with colorectal cancer: Systematic Literature Review.
da Silva Bezerra KH; de Oliveira MVL; do Nascimento IJB; de Barros Rocha L; de Souza Filho LEC; Rocha RSB; da Silva ML; da Costa Cunha K
J Gastrointest Cancer; 2021 Mar; 52(1):17-22. PubMed ID: 32901444
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8. Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF-1α Mediated cancer Cell Viability and Vascularization.
Ratnayake R; Gunasekera SP; Ma JJ; Dang LH; Carney TJ; Paul VJ; Luesch H
Chembiochem; 2020 Aug; 21(16):2356-2366. PubMed ID: 32237262
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9. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
Ban HS; Kim BK; Lee H; Kim HM; Harmalkar D; Nam M; Park SK; Lee K; Park JT; Kim I; Lee K; Hwang GS; Won M
Cell Death Dis; 2017 Jun; 8(6):e2843. PubMed ID: 28569777
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10. The BH3-mimetic obatoclax reduces HIF-1α levels and HIF-1 transcriptional activity and sensitizes hypoxic colon adenocarcinoma cells to 5-fluorouracil.
Gariboldi MB; Taiana E; Bonzi MC; Craparotta I; Giovannardi S; Mancini M; Monti E
Cancer Lett; 2015 Aug; 364(2):156-64. PubMed ID: 25979228
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11. Monoclonal antibody G250 targeting CA Ⅸ: Binding specificity, internalization and therapeutic effects in a non-renal cancer model.
Zatovicova M; Jelenska L; Hulikova A; Ditte P; Ditte Z; Csaderova L; Svastova E; Schmalix W; Boettger V; Bevan P; Pastorek J; Pastorekova S
Int J Oncol; 2014 Dec; 45(6):2455-67. PubMed ID: 25230982
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12. Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy.
de Haas S; Delmar P; Bansal AT; Moisse M; Miles DW; Leighl N; Escudier B; Van Cutsem E; Carmeliet P; Scherer SJ; Pallaud C; Lambrechts D
Angiogenesis; 2014 Oct; 17(4):909-20. PubMed ID: 25012543
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13. SDH mutations establish a hypermethylator phenotype in paraganglioma.
Letouzé E; Martinelli C; Loriot C; Burnichon N; Abermil N; Ottolenghi C; Janin M; Menara M; Nguyen AT; Benit P; Buffet A; Marcaillou C; Bertherat J; Amar L; Rustin P; De Reyniès A; Gimenez-Roqueplo AP; Favier J
Cancer Cell; 2013 Jun; 23(6):739-52. PubMed ID: 23707781
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14. LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of vhl in a colon cancer cell line.
Lee K; Kang JE; Park SK; Jin Y; Chung KS; Kim HM; Lee K; Kang MR; Lee MK; Song KB; Yang EG; Lee JJ; Won M
Biochem Pharmacol; 2010 Oct; 80(7):982-9. PubMed ID: 20599784
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15. Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients.
Fransén K; Fenech M; Fredrikson M; Dabrosin C; Söderkvist P
Mol Carcinog; 2006 Nov; 45(11):833-40. PubMed ID: 16865676
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16. Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
Jakubicková L; Biesová Z; Pastoreková S; Kettmann R; Pastorek J
Int J Oncol; 2005 Apr; 26(4):1121-7. PubMed ID: 15754010
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