BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Treatment
1766 results:

  • 1. pH-responsive targeted nanoparticles release ERK-inhibitor in the hypoxic zone and sensitize free gemcitabine in mutant K-Ras-addicted pancreatic cancer cells and mouse model.
    Dutta D; Ray P; De A; Ghosh A; Hazra RS; Ghosh P; Banerjee S; Diaz FJ; Upadhyay SP; Quadir M; Banerjee SK
    PLoS One; 2024; 19(4):e0297749. PubMed ID: 38687749
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Tumour-derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13-CCR2-M2 macrophage axis.
    Liang H; Geng S; Wang Y; Fang Q; Xin Y; Li Y
    J Cell Mol Med; 2024 May; 28(9):e18315. PubMed ID: 38680032
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Biological functions of LncRNA SNHG14 in the development of thyroid cancer cells via targeting miR-206.
    Sang Y; Min R; Huang T; Zhang J
    Cell Mol Biol (Noisy-le-grand); 2024 Apr; 70(4):77-84. PubMed ID: 38678623
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Identification of core genes of craniopharyngioma angiogenesis based on single-cell nuclear transcriptome sequencing.
    Zhang J; Xu L; Ye J; Xu C; Wu B; Wu J; Hong T
    Cell Mol Biol (Noisy-le-grand); 2024 Mar; 70(3):136-141. PubMed ID: 38650143
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Nuclear MAST4 Suppresses FOXO3 through Interaction with akt3 and Induces Chemoresistance in Pancreatic Ductal Carcinoma.
    Fujiwara-Tani R; Sasaki T; Bhawal UK; Mori S; Ogata R; Sasaki R; Ikemoto A; Kishi S; Fujii K; Ohmori H; Sho M; Kuniyasu H
    Int J Mol Sci; 2024 Apr; 25(7):. PubMed ID: 38612866
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. CDK4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma.
    Cheng K; Zhou Z; Chen Q; Chen Z; Cai Y; Cai H; Wu S; Gao P; Cai Y; Zhou J; Wang X; Wu Z; Peng B
    Sci Rep; 2024 Apr; 14(1):8389. PubMed ID: 38600093
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The nanobody targeting PD-L1 and CXCR4 counteracts pancreatic stellate cell-mediated tumour progression by disrupting tumour microenvironment.
    Li Y; Zheng Y; Xu S; Hu H; Peng L; Zhu J; Wu M
    Int Immunopharmacol; 2024 May; 132():111944. PubMed ID: 38581990
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The emerging role and clinical significance of circRNAs in papillary thyroid cancer.
    Ma J; Xu J; Zhang X; Quan J
    Front Endocrinol (Lausanne); 2024; 15():1351776. PubMed ID: 38544689
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. PELI1: key players in the oncogenic characteristics of pancreatic cancer.
    Fei X; Zhu C; Liu P; Liu S; Ren L; Lu R; Hou J; Gao Y; Wang X; Pan Y
    J Exp Clin Cancer Res; 2024 Mar; 43(1):91. PubMed ID: 38528516
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Nanodrug-bacteria conjugates-mediated oncogenic collagen depletion enhances immune checkpoint blockade therapy against pancreatic cancer.
    Li Z; Mo F; Guo K; Ren S; Wang Y; Chen Y; Schwartz PB; Richmond N; Liu F; Ronnekleiv-Kelly SM; Hu Q
    Med; 2024 Apr; 5(4):348-367.e7. PubMed ID: 38521069
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. A novel SIK2 inhibitor SIC-19 exhibits synthetic lethality with PARP inhibitors in ovarian cancer.
    Wang F; Yu X; Qian J; Cao Y; Dong S; Zhan S; Lu Z; Bast RC; Song Q; Chen Y; Zhang Y; Zhou J
    Drug Resist Updat; 2024 May; 74():101077. PubMed ID: 38518726
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by akt inhibition.
    Deben C; Boullosa LF; Fortes FR; De La Hoz EC; Le Compte M; Seghers S; Peeters M; Vanlanduit S; Lin A; Dijkstra KK; Van Schil P; Hendriks JMH; Prenen H; Roeyen G; Lardon F; Smits E
    J Exp Clin Cancer Res; 2024 Mar; 43(1):88. PubMed ID: 38515178
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A novel DDIT3 activator dehydroevodiamine effectively inhibits tumor growth and tumor cell stemness in pancreatic cancer.
    Zhu SL; Qi M; Chen MT; Lin JP; Huang HF; Deng LJ; Zhou XW
    Phytomedicine; 2024 Jun; 128():155377. PubMed ID: 38503154
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Natural products and derivatives in renal, urothelial and testicular cancers: Targeting signaling pathways and therapeutic potential.
    Li D; Wang J; Tuo Z; Yoo KH; Yu Q; Miyamoto A; Zhang C; Ye X; Wei W; Wu R; Feng D
    Phytomedicine; 2024 May; 127():155503. PubMed ID: 38490077
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures.
    Rausio H; Cervera A; Heuser VD; West G; Oikkonen J; Pianfetti E; Lovino M; Ficarra E; Taimen P; Hynninen J; Lehtonen R; Hautaniemi S; Carpén O; Huhtinen K
    Neoplasia; 2024 May; 51():100987. PubMed ID: 38489912
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. akting on R Loops Makes for an ATractive Target in Ovarian cancer Therapy.
    Ramanarayanan V; Oberdoerffer P
    Cancer Res; 2024 Mar; 84(6):793-795. PubMed ID: 38486481
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Activation of the PI3K/akt signaling pathway by ARNTL2 enhances cellular glycolysis and sensitizes pancreatic adenocarcinoma to erlotinib.
    Ge W; Wang Y; Quan M; Mao T; Bischof EY; Xu H; Zhang X; Li S; Yue M; Ma J; Yang H; Wang L; Yu Z; Wang L; Cui J
    Mol Cancer; 2024 Mar; 23(1):48. PubMed ID: 38459558
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. TOP2A modulates signaling via the akt/mTOR pathway to promote ovarian cancer cell proliferation.
    Zhang K; Zheng X; Sun Y; Feng X; Wu X; Liu W; Gao C; Yan Y; Tian W; Wang Y
    Cancer Biol Ther; 2024 Dec; 25(1):2325126. PubMed ID: 38445610
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Periostin's role in uterine leiomyoma development: a mini-review on the potential periostin poses as a pharmacological intervention for uterine leiomyoma.
    Kiesler ZG; Hunter MI; Balboula AZ; Patterson AL
    Arch Gynecol Obstet; 2024 May; 309(5):1825-1831. PubMed ID: 38441600
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. GSG2 promotes thyroid cancer via stabilizing AURKB and activating akt pathway.
    Zhang F; Huang C
    Aging (Albany NY); 2024 Mar; 16(6):5091-5107. PubMed ID: 38441546
    [TBL] [Abstract] [Full Text] [Related]  


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