BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716
59 results:

  • 1. Ruxolitinib induces apoptosis and pyroptosis of anaplastic thyroid cancer via the transcriptional inhibition of DRP1-mediated mitochondrial fission.
    Guo YW; Zhu L; Duan YT; Hu YQ; Li LB; Fan WJ; Song FH; Cai YF; Liu YY; Zheng GW; Ge MH
    Cell Death Dis; 2024 Feb; 15(2):125. PubMed ID: 38336839
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation.
    Lee M; Morris LG
    Oncotarget; 2024 Jan; 15():36-48. PubMed ID: 38275291
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Multifactor assessment of ovarian cancer reveals immunologically interpretable molecular subtypes with distinct prognoses.
    Guo Y; Li S; Li C; Wang L; Ning W
    Front Immunol; 2023; 14():1326018. PubMed ID: 38143770
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Mechanisms of carboplatin- and paclitaxel-dependent induction of premature senescence and pro-cancerogenic conversion of normal peritoneal mesothelium and fibroblasts.
    Rutecki S; Pakuła-Iwańska M; Leśniewska-Bocianowska A; Matuszewska J; Rychlewski D; Uruski P; Stryczyński Ł; Naumowicz E; Szubert S; Tykarski A; Mikuła-Pietrasik J; Książek K
    J Pathol; 2024 Feb; 262(2):198-211. PubMed ID: 37941520
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. RARγ promotes the invasion and metastasis of thyroid carcinoma by activating the jak1-STAT3-CD24/MMPs axis.
    Zhang FX; Xu P; Zhang LJ; Fan R; Zhang HX; Liu DH; Liu K; Shen DY
    Int Immunopharmacol; 2023 Dec; 125(Pt A):111129. PubMed ID: 37897947
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. m6A-modified circNFIX promotes ovarian cancer progression and immune escape via activating IL-6R/jak1/STAT3 signaling by sponging miR-647.
    Wang R; Ye H; Yang B; Ao M; Yu X; Wu Y; Xi M; Hou M
    Int Immunopharmacol; 2023 Nov; 124(Pt A):110879. PubMed ID: 37713785
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma.
    Fu D; Yan J; Zhang Z; Liu Y; Ma X; Ding J; Yang S; Zhao R; Chang A; Gao C; Liu J; Zhao T; Wang X; Huang C; Gao S; Ma Y; Tang B; Feng Y; Wang H; Hao J
    Cancer Biol Med; 2023 Jun; 20(8):599-626. PubMed ID: 37381714
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. IFNγ induces Bcl3 expression by jak1/STAT1/p65 signaling, resulting in increased IL-8 expression in ovarian cancer cells.
    Gaire B; Padmanabhan S; Zou Y; Uddin MM; Reddy SU; Vancurova I
    FEBS Open Bio; 2023 Aug; 13(8):1495-1506. PubMed ID: 37151134
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Inhibition of ALK-Signaling Overcomes STRN-ALK-Induced Downregulation of the Sodium Iodine Symporter and Restores Radioiodine Uptake in Thyroid Cells.
    Nikitski AV; Condello V; Divakaran SS; Nikiforov YE
    Thyroid; 2023 Apr; 33(4):464-473. PubMed ID: 36585857
    [No Abstract]    [Full Text] [Related]  

  • 10. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma.
    Di Giorgio C; Lupia A; Marchianò S; Bordoni M; Bellini R; Massa C; Urbani G; Roselli R; Moraca F; Sepe V; Catalanotti B; Morretta E; Monti MC; Biagioli M; Distrutti E; Zampella A; Fiorucci S
    Cells; 2022 Nov; 11(21):. PubMed ID: 36359879
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors.
    Zhang F; Zhang Q; Zhu J; Yao B; Ma C; Qiao N; He S; Ye Z; Wang Y; Han R; Feng J; Wang Y; Qin Z; Ma Z; Li K; Zhang Y; Tian S; Chen Z; Tan S; Wu Y; Ran P; Wang Y; Ding C; Zhao Y
    Cell Res; 2022 Dec; 32(12):1047-1067. PubMed ID: 36307579
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer.
    Akl L; Abd El-Hafeez AA; Ibrahim TM; Salem R; Marzouk HMM; El-Domany RA; Ghosh P; Eldehna WM; Abou-Seri SM
    Eur J Med Chem; 2022 Dec; 243():114704. PubMed ID: 36095992
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Extracellular vesicle-packaged miR-181c-5p from epithelial ovarian cancer cells promotes M2 polarization of tumor-associated macrophages via the KAT2B/HOXA10 axis.
    Yang S; Zhao H; Xiao W; Shao L; Zhao C; Sun P
    J Gene Med; 2022 Oct; 24(10):e3446. PubMed ID: 36027869
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. IFNγ-induced PD-L1 expression in ovarian cancer cells is regulated by jak1, STAT1 and IRF1 signaling.
    Padmanabhan S; Gaire B; Zou Y; Uddin MM; Vancurova I
    Cell Signal; 2022 Sep; 97():110400. PubMed ID: 35820543
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Postoperative hyperprogression disease of pancreatic ductal adenocarcinoma after curative resection: a retrospective cohort study.
    Zou S; Wang X; Chen H; Lin J; Wen C; Zhan Q; Chen H; Lu X; Deng X; Shen B
    BMC Cancer; 2022 Jun; 22(1):649. PubMed ID: 35698045
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic cancer Risk.
    Tian J; Chen C; Rao M; Zhang M; Lu Z; Cai Y; Ying P; Li B; Wang H; Wang L; Li Y; Huang J; Fan L; Cai X; Ning C; Li Y; Zhang F; Wang W; Jiang Y; Liu Y; Wang M; Li H; Huang C; Yang Z; Chang J; Zhu Y; Yang X; Miao X
    Cancer Res; 2022 Jun; 82(11):2084-2096. PubMed ID: 35363263
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and jak1/Stat3 signaling.
    Safari F; Shafiee Nejad N; Aghaei Nejad A
    Med Oncol; 2022 Jan; 39(3):28. PubMed ID: 35059869
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. IFNγ induces jak1/STAT1/p65 NFκB-dependent interleukin-8 expression in ovarian cancer cells, resulting in their increased migration.
    Padmanabhan S; Gaire B; Zou Y; Uddin MM; DeLeon D; Vancurova I
    Int J Biochem Cell Biol; 2021 Dec; 141():106093. PubMed ID: 34626802
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. IL-10 derived from Hepatocarcinoma cells improves human induced regulatory T cells function via jak1/STAT5 pathway in tumor microenvironment.
    Zhang S; Gan X; Qiu J; Ju Z; Gao J; Zhou J; Shi C; Zhu Y; Li Z
    Mol Immunol; 2021 May; 133():163-172. PubMed ID: 33667986
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. SHP1 Decreases Level of P-STAT3 (Ser727) and Inhibits Proliferation and Migration of Pancreatic cancer Cells.
    Zhang M; Hu X; Kang Y; Wang Z; Zhou W; Liu C; Yang X
    J Environ Pathol Toxicol Oncol; 2021; 40(1):17-27. PubMed ID: 33639070
    [TBL] [Abstract] [Full Text] [Related]  


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