BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND JAK2, ENSG00000096968, O60674, JTK10, 3717 AND Prognosis
22 results:

  • 1. Corosolic acid enhances oxidative stress-induced apoptosis and senescence in pancreatic cancer cells by inhibiting the jak2/STAT3 pathway.
    Luo X; Ye Z; Xu C; Chen H; Dai S; Chen W; Bao G
    Mol Biol Rep; 2024 Jan; 51(1):176. PubMed ID: 38252208
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. ANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the jak2/STAT3 pathway and interacting with ESM1.
    Li YK; Gao AB; Zeng T; Liu D; Zhang QF; Ran XM; Tang ZZ; Li Y; Liu J; Zhang T; Shi GQ; Zhou WC; Zou WD; Peng J; Zhang J; Li H; Zou J
    J Transl Med; 2024 Jan; 22(1):46. PubMed ID: 38212795
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis.
    Huang C; Li H; Xu Y; Xu C; Sun H; Li Z; Ge Y; Wang H; Zhao T; Gao S; Wang X; Yang S; Sun P; Liu Z; Liu J; Chang A; Hao J
    Signal Transduct Target Ther; 2023 Jul; 8(1):271. PubMed ID: 37443111
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. STAT3 signaling in pancreatic ductal adenocarcinoma: a candidate therapeutic target.
    Al-Hetty HRAK; Abdulameer SJ; Alkubaisy SA; Zaid SA; Jalil AT; Jasim IK
    Pathol Res Pract; 2023 May; 245():154425. PubMed ID: 37019018
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma.
    Sun X; Chu H; Lei K; Ci Y; Lu H; Wang J; Zhou M; Ren H; Zheng T
    Pancreatology; 2022 Sep; 22(6):749-759. PubMed ID: 35717305
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion.
    Marimuthu S; Lakshmanan I; Muniyan S; Gautam SK; Nimmakayala RK; Rauth S; Atri P; Shah A; Bhyravbhatla N; Mallya K; Grandgenett PM; Hollingsworth MA; Datta K; Jain M; Ponnusamy MP; Batra SK
    Mol Cancer Res; 2022 Aug; 20(8):1208-1221. PubMed ID: 35533267
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Serum  JAK/STAT profile is related to the IL expression but not with the outcome in pancreatic adenocarcinoma patients.
    Petrusel L; Ilies M; Leucuta D; Rusu I; Seicean A; Iuga C; Seicean R
    Cell Mol Biol (Noisy-le-grand); 2021 Nov; 67(3):107-112. PubMed ID: 34933726
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. ALKBH5-HOXA10 loop-mediated jak2 m6A demethylation and cisplatin resistance in epithelial ovarian cancer.
    Nie S; Zhang L; Liu J; Wan Y; Jiang Y; Yang J; Sun R; Ma X; Sun G; Meng H; Xu M; Cheng W
    J Exp Clin Cancer Res; 2021 Sep; 40(1):284. PubMed ID: 34496932
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. SENP1-mediated deSUMOylation of jak2 regulates its kinase activity and platinum drug resistance.
    Li J; Wu R; Yung MMH; Sun J; Li Z; Yang H; Zhang Y; Liu SS; Cheung ANY; Ngan HYS; Braisted JC; Zheng W; Wei H; Gao Y; Nemes P; Pei H; Chan DW; Li Y; Zhu W
    Cell Death Dis; 2021 Apr; 12(4):341. PubMed ID: 33795649
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Triptolide inhibits jak2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells.
    Zhong Y; Le F; Cheng J; Luo C; Zhang X; Wu X; Xu F; Zuo Q; Tan B
    Oncol Rep; 2021 May; 45(5):. PubMed ID: 33760192
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. High jak2 Protein Expression Predicts a Poor prognosis in Patients with Resectable Pancreatic Ductal Adenocarcinoma.
    Song Y; Tang MY; Chen W; Wang Z; Wang SL
    Dis Markers; 2020; 2020():7656031. PubMed ID: 33029256
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. MiR-203 regulates proliferation and apoptosis of ovarian cancer cells by targeting SOCS3.
    Liu HP; Zhang Y; Liu ZT; Qi H; Zheng XM; Qi LH; Wang JY
    Eur Rev Med Pharmacol Sci; 2019 Nov; 23(21):9286-9294. PubMed ID: 31773696
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Inhibition of jak2/STAT3 and activation of caspase‑9/3 are involved in KYS05090S‑induced apoptosis in ovarian cancer cells.
    Kim BI; Kim JH; Sim DY; Nam M; Jung JH; Shim B; Lee J; Kim SH
    Int J Oncol; 2019 Jul; 55(1):203-210. PubMed ID: 31059018
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
    Song Y; Gao L; Tang Z; Li H; Sun B; Chu P; Qaed E; Ma X; Peng J; Wang S; Hu M; Tang Z
    J Cell Physiol; 2018 Jan; 234(1):777-788. PubMed ID: 30078206
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Autocrine activation of jak2 by IL-11 promotes platinum drug resistance.
    Zhou W; Sun W; Yung MMH; Dai S; Cai Y; Chen CW; Meng Y; Lee JB; Braisted JC; Xu Y; Southall NT; Shinn P; Huang X; Song Z; Chen X; Kai Y; Cai X; Li Z; Hao Q; Cheung ANY; Ngan HYS; Liu SS; Barak S; Hao J; Dai Z; Tzatsos A; Peng W; Pei H; Han Z; Chan DW; Zheng W; Zhu W
    Oncogene; 2018 Jul; 37(29):3981-3997. PubMed ID: 29662190
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. MUC16 C terminal-induced secretion of tumor-derived IL-6 contributes to tumor-associated Treg enrichment in pancreatic cancer.
    Fan K; Yang C; Fan Z; Huang Q; Zhang Y; Cheng H; Jin K; Lu Y; Wang Z; Luo G; Yu X; Liu C
    Cancer Lett; 2018 Apr; 418():167-175. PubMed ID: 29337110
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Fractalkine/CX3CR1 axis modulated the development of pancreatic ductal adenocarcinoma via JAK/STAT signaling pathway.
    Huang L; Ma B; Ma J; Wang F
    Biochem Biophys Res Commun; 2017 Dec; 493(4):1510-1517. PubMed ID: 28986258
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Which patients with para-aortic lymph node (LN16) metastasis will truly benefit from curative pancreaticoduodenectomy for pancreatic head cancer?
    Liu C; Lu Y; Luo G; Cheng H; Guo M; Liu Z; Xu J; Long J; Liu L; Fu D; Ni Q; Li M; Yu X
    Oncotarget; 2016 May; 7(20):29177-86. PubMed ID: 27081079
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer.
    Niu Z; Wang M; Zhou L; Yao L; Liao Q; Zhao Y
    Sci Rep; 2015 Nov; 5():16067. PubMed ID: 26530532
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic cancer for Whom Therapy With Gemcitabine Has Failed.
    Hurwitz HI; Uppal N; Wagner SA; Bendell JC; Beck JT; Wade SM; Nemunaitis JJ; Stella PJ; Pipas JM; Wainberg ZA; Manges R; Garrett WM; Hunter DS; Clark J; Leopold L; Sandor V; Levy RS
    J Clin Oncol; 2015 Dec; 33(34):4039-47. PubMed ID: 26351344
    [TBL] [Abstract] [Full Text] [Related]  


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