Terms: = Endocrine gland cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
52 results:
1. β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Wang H; Liu J; Zhang Z; Peng J; Wang Z; Yang L; Wang X; Hu S; Hong L
Free Radic Biol Med; 2024 Mar; 214():137-157. PubMed ID: 38364944
[TBL] [Abstract] [Full Text] [Related]
2. Dual-layer spectral detector CT: A noninvasive preoperative tool for predicting histopathological differentiation in pancreatic ductal adenocarcinoma.
Liu W; Xie T; Chen L; Tang W; Zhang Z; Wang Y; Deng W; Xie X; Zhou Z
Eur J Radiol; 2024 Apr; 173():111327. PubMed ID: 38330535
[TBL] [Abstract] [Full Text] [Related]
3. CPT1B maintains redox homeostasis and inhibits ferroptosis to induce gemcitabine resistance via the keap1/NRF2 axis in pancreatic cancer.
Tuerhong A; Xu J; Wang W; Shi S; Meng Q; Hua J; Liu J; Zhang B; Yu X; Liang C
Surgery; 2024 May; 175(5):1264-1275. PubMed ID: 38302326
[TBL] [Abstract] [Full Text] [Related]
4. A Morpholine Derivative N-(4-Morpholinomethylene)ethanesulfonamide Induces Ferroptosis in Tumor Cells by Targeting NRF2.
Sun B; Zhang L; Wu B; Luo X
Biol Pharm Bull; 2024 Feb; 47(2):417-426. PubMed ID: 38296488
[TBL] [Abstract] [Full Text] [Related]
5. Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors.
Wang X; Su S; Zhu Y; Cheng X; Cheng C; Chen L; Lei A; Zhang L; Xu Y; Ye D; Zhang Y; Li W; Zhang J
Nat Commun; 2023 Sep; 14(1):5778. PubMed ID: 37723178
[TBL] [Abstract] [Full Text] [Related]
6. Immunotoxicity induced by triclocarban exposure in zebrafish triggering the risk of pancreatic cancer.
Wang H; Li X; Wang W; Xu J; Ai W; Huang H; Wang X
Environ Pollut; 2023 May; 325():121458. PubMed ID: 36934961
[TBL] [Abstract] [Full Text] [Related]
7. Natural and synthetic compounds in Ovarian cancer: A focus on NRF2/keap1 pathway.
Tossetta G; Marzioni D
Pharmacol Res; 2022 Sep; 183():106365. PubMed ID: 35901941
[TBL] [Abstract] [Full Text] [Related]
8. Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.
Yang PW; Xu PL; Cheng CS; Jiao JY; Wu Y; Dong S; Xie J; Zhu XY
J Ethnopharmacol; 2022 Oct; 297():115516. PubMed ID: 35817247
[TBL] [Abstract] [Full Text] [Related]
9. Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic cancer.
Wang X; Li Y; Li Z; Lin S; Wang H; Sun J; Lan C; Wu L; Sun D; Huang C; Singh PK; Hempel N; Trebak M; DeNicola GM; Hao J; Yang S
Cancer Res; 2022 Jun; 82(12):2254-2268. PubMed ID: 35413105
[TBL] [Abstract] [Full Text] [Related]
10. Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through keap1-mediated Nrf2 ubiquitination degradation.
Sun C; Han B; Zhai Y; Zhao H; Li X; Qian J; Hao X; Liu Q; Shen J; Kai G
Free Radic Biol Med; 2022 Feb; 180():220-235. PubMed ID: 35074488
[TBL] [Abstract] [Full Text] [Related]
11. Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic cancer Cells to Glutaminase Inhibition.
Hamada S; Matsumoto R; Tanaka Y; Taguchi K; Yamamoto M; Masamune A
Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33672789
[TBL] [Abstract] [Full Text] [Related]
12. Physical plasma-derived oxidants sensitize pancreatic cancer cells to ferroptotic cell death.
Kumar N; Perez-Novo C; Shaw P; Logie E; Privat-Maldonado A; Dewilde S; Smits E; Berghe WV; Bogaerts A
Free Radic Biol Med; 2021 Apr; 166():187-200. PubMed ID: 33636332
[TBL] [Abstract] [Full Text] [Related]
13. ATDC binds to keap1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer.
Purohit V; Wang L; Yang H; Li J; Ney GM; Gumkowski ER; Vaidya AJ; Wang A; Bhardwaj A; Zhao E; Dolgalev I; Zamperone A; Abel EV; Magliano MPD; Crawford HC; Diolaiti D; Papagiannakopoulos TY; Lyssiotis CA; Simeone DM
Genes Dev; 2021 Feb; 35(3-4):218-233. PubMed ID: 33446568
[TBL] [Abstract] [Full Text] [Related]
14. Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis.
Küper A; Baumann J; Göpelt K; Baumann M; Sänger C; Metzen E; Kranz P; Brockmeier U
Cell Death Dis; 2021 Jan; 12(1):82. PubMed ID: 33441543
[TBL] [Abstract] [Full Text] [Related]
15. Magnetic Resonance Imaging May Be Able to Identify the Origin of Neuroendocrine Tumor Liver Metastases.
Barat M; Soyer P; Al Sharhan F; Terris B; Oudjit A; Gaujoux S; Coriat R; Hoeffel C; Dohan A
Neuroendocrinology; 2021; 111(11):1099-1110. PubMed ID: 33190136
[TBL] [Abstract] [Full Text] [Related]
16. The p.Ser64Leu and p.Pro104Leu missense variants of PALB2 identified in familial pancreatic cancer patients compromise the DNA damage response.
Zhang Y; Park JY; Zhang F; Olson SH; Orlow I; Li Y; Kurtz RC; Ladanyi M; Chen J; Toland AE; Zhang L; Andreassen PR
Hum Mutat; 2021 Feb; 42(2):150-163. PubMed ID: 33169439
[TBL] [Abstract] [Full Text] [Related]
17. FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner.
Du J; Fu L; Ji F; Wang C; Liu S; Qiu X
Life Sci; 2020 Oct; 259():118374. PubMed ID: 32891613
[TBL] [Abstract] [Full Text] [Related]
18. KAT6A amplifications are associated with shorter progression-free survival and overall survival in patients with endometrial serous carcinoma.
Saglam O; Tang Z; Tang G; Medeiros LJ; Toruner GA
PLoS One; 2020; 15(9):e0238477. PubMed ID: 32877461
[TBL] [Abstract] [Full Text] [Related]
19. Ailanthone increases oxidative stress in CDDP-resistant ovarian and bladder cancer cells by inhibiting of Nrf2 and YAP expression through a post-translational mechanism.
Cucci MA; Grattarola M; Dianzani C; Damia G; Ricci F; Roetto A; Trotta F; Barrera G; Pizzimenti S
Free Radic Biol Med; 2020 Apr; 150():125-135. PubMed ID: 32101771
[TBL] [Abstract] [Full Text] [Related]
20. Inhibition of LONP1 protects against erastin-induced ferroptosis in Pancreatic ductal adenocarcinoma PANC1 cells.
Wang H; Liu C; Zhao Y; Zhang W; Xu K; Li D; Zhou Y; Li H; Xiao G; Lu B; Gao G
Biochem Biophys Res Commun; 2020 Feb; 522(4):1063-1068. PubMed ID: 31822343
[TBL] [Abstract] [Full Text] [Related]
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