BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132 AND Treatment
10 results:

  • 1. β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
    Wang H; Liu J; Zhang Z; Peng J; Wang Z; Yang L; Wang X; Hu S; Hong L
    Free Radic Biol Med; 2024 Mar; 214():137-157. PubMed ID: 38364944
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. CPT1B maintains redox homeostasis and inhibits ferroptosis to induce gemcitabine resistance via the keap1/NRF2 axis in pancreatic cancer.
    Tuerhong A; Xu J; Wang W; Shi S; Meng Q; Hua J; Liu J; Zhang B; Yu X; Liang C
    Surgery; 2024 May; 175(5):1264-1275. PubMed ID: 38302326
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.
    Yang PW; Xu PL; Cheng CS; Jiao JY; Wu Y; Dong S; Xie J; Zhu XY
    J Ethnopharmacol; 2022 Oct; 297():115516. PubMed ID: 35817247
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic cancer.
    Wang X; Li Y; Li Z; Lin S; Wang H; Sun J; Lan C; Wu L; Sun D; Huang C; Singh PK; Hempel N; Trebak M; DeNicola GM; Hao J; Yang S
    Cancer Res; 2022 Jun; 82(12):2254-2268. PubMed ID: 35413105
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis.
    Küper A; Baumann J; Göpelt K; Baumann M; Sänger C; Metzen E; Kranz P; Brockmeier U
    Cell Death Dis; 2021 Jan; 12(1):82. PubMed ID: 33441543
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Ailanthone increases oxidative stress in CDDP-resistant ovarian and bladder cancer cells by inhibiting of Nrf2 and YAP expression through a post-translational mechanism.
    Cucci MA; Grattarola M; Dianzani C; Damia G; Ricci F; Roetto A; Trotta F; Barrera G; Pizzimenti S
    Free Radic Biol Med; 2020 Apr; 150():125-135. PubMed ID: 32101771
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to keap1.
    Arora R; Sawney S; Saini V; Steffi C; Tiwari M; Saluja D
    Mol Cancer; 2016 Oct; 15(1):64. PubMed ID: 27756327
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. cancer Stem Cell Properties as Factors Predictive of Chemoresistance in Neoadjuvantly-treated Patients with Ovarian cancer.
    Pylväs-Eerola M; Liakka A; Puistola U; Koivunen J; Karihtala P
    Anticancer Res; 2016 Jul; 36(7):3425-31. PubMed ID: 27354603
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The role of the catecholic and the electrophilic moieties of caffeic acid in Nrf2/keap1 pathway activation in ovarian carcinoma cell lines.
    Sirota R; Gibson D; Kohen R
    Redox Biol; 2015; 4():48-59. PubMed ID: 25498967
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. miR-141 regulates keap1 and modulates cisplatin sensitivity in ovarian cancer cells.
    van Jaarsveld MT; Helleman J; Boersma AW; van Kuijk PF; van Ijcken WF; Despierre E; Vergote I; Mathijssen RH; Berns EM; Verweij J; Pothof J; Wiemer EA
    Oncogene; 2013 Sep; 32(36):4284-93. PubMed ID: 23045278
    [TBL] [Abstract] [Full Text] [Related]  


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