Terms: = Endocrine gland cancer AND MAP2K2, MEK2, 5605, ENSG00000126934, P36507, MKK2, MAPKK2, PRKMK2
23 results:
1. Inhibition of USP21 leads to ovarian carcinoma cell death by suppressing MAPK signaling.
Sun X; Yu J; Cui X; Tang Y; Yu Y
Biotechnol Appl Biochem; 2024 Feb; 71(1):232-239. PubMed ID: 37964466
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2. Characterization of the genomic alterations in poorly differentiated thyroid cancer.
Lee Y; Moon S; Seok JY; Lee JH; Nam S; Chung YS
Sci Rep; 2023 Nov; 13(1):19154. PubMed ID: 37932340
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3. Development and validation of cuproptosis-related lncRNAs associated with pancreatic cancer immune microenvironment based on single-cell.
Sun Y; Yao L; Man C; Gao Z; He R; Fan Y
Front Immunol; 2023; 14():1220760. PubMed ID: 37822927
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4. KMT2C mutation in a Chinese man with primary multidrug-resistant metastatic adenocarcinoma of rete testis: a case report.
Zhang Y; He X; Gao H
BMC Urol; 2022 Aug; 22(1):123. PubMed ID: 35945529
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5. Potential benefit of treatment with MEK inhibitors and chemotherapy in BRAF-mutated KRAS wild-type pancreatic ductal adenocarcinoma patients: a case report.
Ardalan B; Azqueta JI; England J; Eatz TA
Cold Spring Harb Mol Case Stud; 2021 Oct; 7(5):. PubMed ID: 34667063
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6. Genetic and epigenetic characterization of posterior pituitary tumors.
Schmid S; Solomon DA; Perez E; Thieme A; Kleinschmidt-DeMasters BK; Giannini C; Reinhardt A; Asa SL; Mete O; Stichel D; Siewert C; Dittmayer C; Hasselblatt M; Paulus W; Nagel C; Harter PN; Schittenhelm J; Honegger J; Rushing E; Coras R; Pfister SM; Buslei R; Koch A; Perry A; Jones DTW; von Deimling A; Capper D; Lopes MB
Acta Neuropathol; 2021 Dec; 142(6):1025-1043. PubMed ID: 34661724
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7. Phase II study of selumetinib, an orally active inhibitor of MEK1 and mek2 kinases, in KRAS
Kenney C; Kunst T; Webb S; Christina D; Arrowood C; Steinberg SM; Mettu NB; Kim EJ; Rudloff U
Invest New Drugs; 2021 Jun; 39(3):821-828. PubMed ID: 33405090
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8. Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
Wu M; Tan X; Liu P; Yang Y; Huang Y; Liu X; Meng X; Yu B; Wu Y; Jin H
Life Sci; 2020 Aug; 255():117857. PubMed ID: 32470446
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9. Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway.
Meng X; Liu P; Wu Y; Liu X; Huang Y; Yu B; Han J; Jin H; Tan X
Bosn J Basic Med Sci; 2020 Feb; 20(1):106-116. PubMed ID: 31242404
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10. Interaction of tRNA with mek2 in pancreatic cancer cells.
Wang X; Chow CR; Ebine K; Lee J; Rosner MR; Pan T; Munshi HG
Sci Rep; 2016 Jun; 6():28260. PubMed ID: 27301426
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11. The Mitogen-Activated Protein Kinase Pathway Facilitates Resistance to the Src Inhibitor Dasatinib in Thyroid cancer.
Beadnell TC; Mishall KM; Zhou Q; Riffert SM; Wuensch KE; Kessler BE; Corpuz ML; Jing X; Kim J; Wang G; Tan AC; Schweppe RE
Mol Cancer Ther; 2016 Aug; 15(8):1952-63. PubMed ID: 27222538
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12. A phase I/Ib study of trametinib (GSK1120212) alone and in combination with gemcitabine in Japanese patients with advanced solid tumors.
Kasuga A; Nakagawa K; Nagashima F; Shimizu T; Naruge D; Nishina S; Kitamura H; Kurata T; Takasu A; Fujisaka Y; Okamoto W; Nishimura Y; Mukaiyama A; Matsushita H; Furuse J
Invest New Drugs; 2015 Oct; 33(5):1058-67. PubMed ID: 26259955
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13. Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer.
Ho AL; Grewal RK; Leboeuf R; Sherman EJ; Pfister DG; Deandreis D; Pentlow KS; Zanzonico PB; Haque S; Gavane S; Ghossein RA; Ricarte-Filho JC; Domínguez JM; Shen R; Tuttle RM; Larson SM; Fagin JA
N Engl J Med; 2013 Feb; 368(7):623-32. PubMed ID: 23406027
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14. Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors.
Dworakowska D; Wlodek E; Leontiou CA; Igreja S; Cakir M; Teng M; Prodromou N; Góth MI; Grozinsky-Glasberg S; Gueorguiev M; Kola B; Korbonits M; Grossman AB
Endocr Relat Cancer; 2009 Dec; 16(4):1329-38. PubMed ID: 19620247
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15. Mutation analysis of BRAF, MEK1 and mek2 in 15 ovarian cancer cell lines: implications for therapy.
Estep AL; Palmer C; McCormick F; Rauen KA
PLoS One; 2007 Dec; 2(12):e1279. PubMed ID: 18060073
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16. Zonula occludens-1 (ZO-1) redistribution is involved in the regulation of cell dissociation in pancreatic cancer cells.
Tan X; Egami H; Ishikawa S; Kurizaki T; Hirota M; Ogawa M
Dig Dis Sci; 2005 Aug; 50(8):1402-9. PubMed ID: 16110828
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17. Arrangement of expression and distribution of tight junction protein claudin-1 in cell dissociation of pancreatic cancer cells.
Tan X; Egami H; Ishikawa S; Kurizaki T; Nakagawa M; Hirota M; Ogawa M
Int J Oncol; 2004 Dec; 25(6):1567-74. PubMed ID: 15547692
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18. Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation.
Tan X; Tamori Y; Egami H; Ishikawa S; Kurizaki T; Takai E; Hirota M; Ogawa M
Oncol Rep; 2004 May; 11(5):993-8. PubMed ID: 15069537
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19. Relationship between the expression of extracellular signal-regulated kinase 1/2 and the dissociation of pancreatic cancer cells: Involvement of ERK1/2 in the dissociation status of cancer cells.
Tan X; Egami H; Ishikawa S; Kurizaki T; Tamori Y; Takai E; Hirota M; Ogawa M
Int J Oncol; 2004 Apr; 24(4):815-20. PubMed ID: 15010817
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20. Involvement of the mitogen-activated protein kinase kinase 2 in the induction of cell dissociation in pancreatic cancer.
Tan X; Egami H; Kamohara H; Ishikawa S; Kurizaki T; Yoshida N; Tamori Y; Takai E; Hirota M; Ogawa M
Int J Oncol; 2004 Jan; 24(1):65-73. PubMed ID: 14654942
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