Terms: = Endocrine gland cancer AND MAP2K2, MEK2, 5605, ENSG00000126934, P36507, MKK2, MAPKK2, PRKMK2 AND Treatment
15 results:
1. Inhibition of USP21 leads to ovarian carcinoma cell death by suppressing MAPK signaling.
Sun X; Yu J; Cui X; Tang Y; Yu Y
Biotechnol Appl Biochem; 2024 Feb; 71(1):232-239. PubMed ID: 37964466
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2. Development and validation of cuproptosis-related lncRNAs associated with pancreatic cancer immune microenvironment based on single-cell.
Sun Y; Yao L; Man C; Gao Z; He R; Fan Y
Front Immunol; 2023; 14():1220760. PubMed ID: 37822927
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3. KMT2C mutation in a Chinese man with primary multidrug-resistant metastatic adenocarcinoma of rete testis: a case report.
Zhang Y; He X; Gao H
BMC Urol; 2022 Aug; 22(1):123. PubMed ID: 35945529
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4. Potential benefit of treatment with MEK inhibitors and chemotherapy in BRAF-mutated KRAS wild-type pancreatic ductal adenocarcinoma patients: a case report.
Ardalan B; Azqueta JI; England J; Eatz TA
Cold Spring Harb Mol Case Stud; 2021 Oct; 7(5):. PubMed ID: 34667063
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5. Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
Wu M; Tan X; Liu P; Yang Y; Huang Y; Liu X; Meng X; Yu B; Wu Y; Jin H
Life Sci; 2020 Aug; 255():117857. PubMed ID: 32470446
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6. The Mitogen-Activated Protein Kinase Pathway Facilitates Resistance to the Src Inhibitor Dasatinib in Thyroid cancer.
Beadnell TC; Mishall KM; Zhou Q; Riffert SM; Wuensch KE; Kessler BE; Corpuz ML; Jing X; Kim J; Wang G; Tan AC; Schweppe RE
Mol Cancer Ther; 2016 Aug; 15(8):1952-63. PubMed ID: 27222538
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7. A phase I/Ib study of trametinib (GSK1120212) alone and in combination with gemcitabine in Japanese patients with advanced solid tumors.
Kasuga A; Nakagawa K; Nagashima F; Shimizu T; Naruge D; Nishina S; Kitamura H; Kurata T; Takasu A; Fujisaka Y; Okamoto W; Nishimura Y; Mukaiyama A; Matsushita H; Furuse J
Invest New Drugs; 2015 Oct; 33(5):1058-67. PubMed ID: 26259955
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8. Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer.
Ho AL; Grewal RK; Leboeuf R; Sherman EJ; Pfister DG; Deandreis D; Pentlow KS; Zanzonico PB; Haque S; Gavane S; Ghossein RA; Ricarte-Filho JC; DomÃnguez JM; Shen R; Tuttle RM; Larson SM; Fagin JA
N Engl J Med; 2013 Feb; 368(7):623-32. PubMed ID: 23406027
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9. Mutation analysis of BRAF, MEK1 and mek2 in 15 ovarian cancer cell lines: implications for therapy.
Estep AL; Palmer C; McCormick F; Rauen KA
PLoS One; 2007 Dec; 2(12):e1279. PubMed ID: 18060073
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10. Zonula occludens-1 (ZO-1) redistribution is involved in the regulation of cell dissociation in pancreatic cancer cells.
Tan X; Egami H; Ishikawa S; Kurizaki T; Hirota M; Ogawa M
Dig Dis Sci; 2005 Aug; 50(8):1402-9. PubMed ID: 16110828
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11. Arrangement of expression and distribution of tight junction protein claudin-1 in cell dissociation of pancreatic cancer cells.
Tan X; Egami H; Ishikawa S; Kurizaki T; Nakagawa M; Hirota M; Ogawa M
Int J Oncol; 2004 Dec; 25(6):1567-74. PubMed ID: 15547692
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12. Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation.
Tan X; Tamori Y; Egami H; Ishikawa S; Kurizaki T; Takai E; Hirota M; Ogawa M
Oncol Rep; 2004 May; 11(5):993-8. PubMed ID: 15069537
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13. Relationship between the expression of extracellular signal-regulated kinase 1/2 and the dissociation of pancreatic cancer cells: Involvement of ERK1/2 in the dissociation status of cancer cells.
Tan X; Egami H; Ishikawa S; Kurizaki T; Tamori Y; Takai E; Hirota M; Ogawa M
Int J Oncol; 2004 Apr; 24(4):815-20. PubMed ID: 15010817
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14. Involvement of the mitogen-activated protein kinase kinase 2 in the induction of cell dissociation in pancreatic cancer.
Tan X; Egami H; Kamohara H; Ishikawa S; Kurizaki T; Yoshida N; Tamori Y; Takai E; Hirota M; Ogawa M
Int J Oncol; 2004 Jan; 24(1):65-73. PubMed ID: 14654942
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15. BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets.
Calhoun ES; Jones JB; Ashfaq R; Adsay V; Baker SJ; Valentine V; Hempen PM; Hilgers W; Yeo CJ; Hruban RH; Kern SE
Am J Pathol; 2003 Oct; 163(4):1255-60. PubMed ID: 14507635
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