Terms: = Endocrine gland cancer AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1 AND Treatment
17 results:
1. Single-cell transcriptome analysis reveals subtype-specific clonal evolution and microenvironmental changes in liver metastasis of pancreatic adenocarcinoma and their clinical implications.
Park JK; Jeong HO; Kim H; Choi JH; Lee EM; Kim S; Jang J; Choi DW; Lee SH; Kim KM; Jang KT; Lee KH; Lee KT; Lee MW; Lee JK; Lee S
Mol Cancer; 2024 May; 23(1):87. PubMed ID: 38702773
[TBL] [Abstract] [Full Text] [Related]
2. mkk4 Inhibitors-Recent Development Status and Therapeutic Potential.
Katzengruber L; Sander P; Laufer S
Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108658
[TBL] [Abstract] [Full Text] [Related]
3. ROS-mediated SRMS activation confers platinum resistance in ovarian cancer.
Jiang Y; Song L; Lin Y; Nowialis P; Gao Q; Li T; Li B; Mao X; Song Q; Xing C; Zheng G; Huang S; Jin L
Oncogene; 2023 May; 42(20):1672-1684. PubMed ID: 37020040
[TBL] [Abstract] [Full Text] [Related]
4. In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer.
Chang CD; Chao MW; Lee HY; Liu YT; Tu HJ; Lien ST; Lin TE; Sung TY; Yen SC; Huang SH; Hsu KC; Pan SL
J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2166039. PubMed ID: 36683274
[TBL] [Abstract] [Full Text] [Related]
5. ACT001 inhibits pituitary tumor growth by inducing autophagic cell death via mek4/MAPK pathway.
Cai L; Wu ZR; Cao L; Xu JD; Lu JL; Wang CD; Jin JH; Wu ZB; Su ZP
Acta Pharmacol Sin; 2022 Sep; 43(9):2386-2396. PubMed ID: 35082393
[TBL] [Abstract] [Full Text] [Related]
6. MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells.
Kleemann M; Schneider H; Unger K; Sander P; Schneider EM; Fischer-Posovszky P; Handrick R; Otte K
Sci Rep; 2018 Jun; 8(1):9020. PubMed ID: 29899543
[TBL] [Abstract] [Full Text] [Related]
7. LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and map2k4.
Liu J; Xu D; Wang Q; Zheng D; Jiang X; Xu L
Dig Dis Sci; 2014 Jul; 59(7):1452-60. PubMed ID: 24532253
[TBL] [Abstract] [Full Text] [Related]
8. Apoptosis signal-regulating kinase 1-thioredoxin complex dissociation by capsaicin causes pancreatic tumor growth suppression by inducing apoptosis.
Pramanik KC; Srivastava SK
Antioxid Redox Signal; 2012 Nov; 17(10):1417-32. PubMed ID: 22530568
[TBL] [Abstract] [Full Text] [Related]
9. Biological and prognostic relevance of mitogen-activated protein kinases in pancreatic adenocarcinoma.
Handra-Luca A; Lesty C; Hammel P; Sauvanet A; Rebours V; Martin A; Fagard R; Fléjou JF; Faivre S; Bédossa P; Ruszniewski P; Couvelard A
Pancreas; 2012 Apr; 41(3):416-21. PubMed ID: 22158075
[TBL] [Abstract] [Full Text] [Related]
10. Analysis of the mitogen-activated protein kinase kinase 4 (map2k4) tumor suppressor gene in ovarian cancer.
Davis SJ; Choong DY; Ramakrishna M; Ryland GL; Campbell IG; Gorringe KL
BMC Cancer; 2011 May; 11():173. PubMed ID: 21575258
[TBL] [Abstract] [Full Text] [Related]
11. mkk4 acts as a potential tumor suppressor in ovarian cancer.
Yeasmin S; Nakayama K; Rahman MT; Rahman M; Ishikawa M; Katagiri A; Iida K; Nakayama N; Miyazaki K
Tumour Biol; 2011 Aug; 32(4):661-70. PubMed ID: 21487811
[TBL] [Abstract] [Full Text] [Related]
12. Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells.
Kreutzer JN; Ruzzene M; Guerra B
BMC Cancer; 2010 Aug; 10():440. PubMed ID: 20718998
[TBL] [Abstract] [Full Text] [Related]
13. Regulation of the metastasis suppressor gene mkk4 in ovarian cancer.
Spillman MA; Lacy J; Murphy SK; Whitaker RS; Grace L; Teaberry V; Marks JR; Berchuck A
Gynecol Oncol; 2007 May; 105(2):312-20. PubMed ID: 17276500
[TBL] [Abstract] [Full Text] [Related]
14. Identification of potential therapeutic targets by gene-expression profiling in pancreatic endocrine tumors.
Couvelard A; Hu J; Steers G; O'Toole D; Sauvanet A; Belghiti J; Bedossa P; Gatter K; Ruszniewski P; Pezzella F
Gastroenterology; 2006 Nov; 131(5):1597-610. PubMed ID: 17064702
[TBL] [Abstract] [Full Text] [Related]
15. A novel biweekly pancreatic cancer treatment schedule with gemcitabine, 5-fluorouracil and folinic acid.
Correale P; Messinese S; Marsili S; Ceciarini F; Pozzessere D; Petrioli R; Sabatino M; Cerretani D; Pellegrini M; Di Palma T; Neri A; Calvanese A; Pinto E; Giorgi G; Francini G
Br J Cancer; 2003 Jul; 89(2):239-42. PubMed ID: 12865908
[TBL] [Abstract] [Full Text] [Related]
16. Progress in cancer genetics: lessons from pancreatic cancer.
Goggins M; Kern SE; Offerhaus JA; Hruban RH
Ann Oncol; 1999; 10 Suppl 4():4-8. PubMed ID: 10436774
[TBL] [Abstract] [Full Text] [Related]
17. Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells.
Wang TH; Popp DM; Wang HS; Saitoh M; Mural JG; Henley DC; Ichijo H; Wimalasena J
J Biol Chem; 1999 Mar; 274(12):8208-16. PubMed ID: 10075725
[TBL] [Abstract] [Full Text] [Related]
