Terms: = Endocrine gland cancer AND MAPK1, MAPK2, 5594, ENSG00000100030, P28482, ERK2, p40, PRKM1, p38, p41, ERT1, p41mapk, PRKM2, P42MAPK, ERK AND Treatment
901 results:
1. Antitumor activity of extracellular signal-regulated kinases 1/2 inhibitor BVD-523 (ulixertinib) on thyroid cancer cells.
Chen Y; Xiao X; Hu G; Liu R; Xue J
J Cancer Res Ther; 2024 Apr; 20(2):570-577. PubMed ID: 38687926
[TBL] [Abstract] [Full Text] [Related]
2. pH-responsive targeted nanoparticles release erk-inhibitor in the hypoxic zone and sensitize free gemcitabine in mutant K-Ras-addicted pancreatic cancer cells and mouse model.
Dutta D; Ray P; De A; Ghosh A; Hazra RS; Ghosh P; Banerjee S; Diaz FJ; Upadhyay SP; Quadir M; Banerjee SK
PLoS One; 2024; 19(4):e0297749. PubMed ID: 38687749
[TBL] [Abstract] [Full Text] [Related]
3. Biological functions of LncRNA SNHG14 in the development of thyroid cancer cells via targeting miR-206.
Sang Y; Min R; Huang T; Zhang J
Cell Mol Biol (Noisy-le-grand); 2024 Apr; 70(4):77-84. PubMed ID: 38678623
[TBL] [Abstract] [Full Text] [Related]
4. CDK4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma.
Cheng K; Zhou Z; Chen Q; Chen Z; Cai Y; Cai H; Wu S; Gao P; Cai Y; Zhou J; Wang X; Wu Z; Peng B
Sci Rep; 2024 Apr; 14(1):8389. PubMed ID: 38600093
[TBL] [Abstract] [Full Text] [Related]
5. TRIM29 facilitates gemcitabine resistance via MEK/erk pathway and is modulated by circRPS29/miR-770-5p axis in PDAC.
Huang W; Hu X; He X; Pan D; Huang Z; Gu Z; Huang G; Wang P; Cui C; Fan Y
Drug Resist Updat; 2024 May; 74():101079. PubMed ID: 38518727
[TBL] [Abstract] [Full Text] [Related]
6. ACA-28, an erk MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic cancer Cells.
Takasaki T; Hamabe Y; Touchi K; Khandakar GI; Ueda T; Okada H; Sakai K; Nishio K; Tanabe G; Sugiura R
Oxid Med Cell Longev; 2024; 2024():7683793. PubMed ID: 38500550
[TBL] [Abstract] [Full Text] [Related]
7. Lactate enhances NMNAT1 lactylation to sustain nuclear NAD
Huang H; Wang S; Xia H; Zhao X; Chen K; Jin G; Zhou S; Lu Z; Chen T; Yu H; Zheng X; Huang H; Lan L
Cancer Lett; 2024 Apr; 588():216806. PubMed ID: 38467179
[TBL] [Abstract] [Full Text] [Related]
8. Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment.
Qiao J; Liu S; Huang Y; Zhu X; Xue C; Wang Y; Xiong H; Yao J
J Colloid Interface Sci; 2024 Jul; 665():477-490. PubMed ID: 38429120
[TBL] [Abstract] [Full Text] [Related]
9. VNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/erk signaling pathway.
Wang Q; Tang Y; Dai A; Li T; Pei Y; Zhang Z; Hu X; Chen T; Chen Q
Appl Microbiol Biotechnol; 2024 Feb; 108(1):218. PubMed ID: 38372808
[TBL] [Abstract] [Full Text] [Related]
10. AKR1C3 silencing inhibits autophagy-dependent glycolysis in thyroid cancer cells by inactivating erk signaling.
Gao Y; Tao W; Wang S; Duan R; Zhang Z
Drug Dev Res; 2024 Feb; 85(1):e22142. PubMed ID: 38349266
[TBL] [Abstract] [Full Text] [Related]
11. Advance in the role of chemokines/chemokine receptors in carcinogenesis: Focus on pancreatic cancer.
Song N; Cui K; Zeng L; Li M; Fan Y; Shi P; Wang Z; Su W; Wang H
Eur J Pharmacol; 2024 Mar; 967():176357. PubMed ID: 38309677
[TBL] [Abstract] [Full Text] [Related]
12. PW06 suppresses cancer cell metastasis in human pancreatic carcinoma MIA PaCa-2 cells via the inhibitions of p-Akt/mTOR/NF-κB and MMP2/MMP9 signaling pathways in vitro.
Huang YP; Yeh CA; Ma YS; Chen PY; Lai KC; Lien JC; Hsieh WT
Environ Toxicol; 2024 May; 39(5):2768-2781. PubMed ID: 38264921
[TBL] [Abstract] [Full Text] [Related]
13. CMTM 6 promotes the development of thyroid cancer by inhibiting NIS activity through activating the MAPK signaling pathway.
Chen X; Shen H; Liu H; Tan L; Zhang N
Funct Integr Genomics; 2024 Jan; 24(1):10. PubMed ID: 38221563
[TBL] [Abstract] [Full Text] [Related]
14. Pan-EGFR Inhibitor Dacomitinib Resensitizes Paclitaxel and Induces Apoptosis via Elevating Intracellular ROS Levels in Ovarian cancer SKOV3-TR Cells.
Lim YJ; Kim HS; Bae S; So KA; Kim TJ; Lee JH
Molecules; 2024 Jan; 29(1):. PubMed ID: 38202856
[TBL] [Abstract] [Full Text] [Related]
15. Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer.
Wu M; Xie J; Xing Y; Zhang L; Chen H; Tang B; Zhou M; Lv S; Huang D; Jian S; Zhou C; Liu M; Guo W; Chen Y; Yi Z
Int J Biol Sci; 2024; 20(2):486-501. PubMed ID: 38169532
[TBL] [Abstract] [Full Text] [Related]
16. DON of Hope: Starving Pancreatic cancer by Glutamine Antagonism.
Pillai R; Papagiannakopoulous T
Cancer Res; 2024 Feb; 84(3):349-350. PubMed ID: 38117482
[TBL] [Abstract] [Full Text] [Related]
17. Blockade of DDR1/PYK2/erk signaling suggesting SH2 superbinder as a novel autophagy inhibitor for pancreatic cancer.
Xu H; Tan M; Hou GQ; Sang YZ; Lin L; Gan XC; Cao X; Liu AD
Cell Death Dis; 2023 Dec; 14(12):811. PubMed ID: 38071340
[TBL] [Abstract] [Full Text] [Related]
18. Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy.
Montenegro MF; Martí-Díaz R; Navarro A; Tolivia J; Sánchez-Del-Campo L; Cabezas-Herrera J; Rodríguez-López JN
Cell Death Dis; 2023 Nov; 14(11):761. PubMed ID: 37996408
[TBL] [Abstract] [Full Text] [Related]
19. Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer.
Cook DP; Galpin KJC; Rodriguez GM; Shakfa N; Wilson-Sanchez J; Echaibi M; Pereira M; Matuszewska K; Haagsma J; Murshed H; Cudmore AO; MacDonald E; Tone A; Shepherd TG; Petrik JJ; Koti M; Vanderhyden BC
Commun Biol; 2023 Nov; 6(1):1152. PubMed ID: 37957414
[TBL] [Abstract] [Full Text] [Related]
20. Targeting ribosome biogenesis reinforces erk-dependent senescence in pancreatic cancer.
Rowell MC; Deschênes-Simard X; Lopes-Paciencia S; Le Calvé B; Kalegari P; Mignacca L; Fernandez-Ruiz A; Guillon J; Lessard F; Bourdeau V; Igelmann S; Duman AM; Stanom Y; Kottakis F; Deshpande V; Krizhanovsky V; Bardeesy N; Ferbeyre G
Cell Cycle; 2023 Oct; 22(19):2172-2193. PubMed ID: 37942963
[TBL] [Abstract] [Full Text] [Related]
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