BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Prognosis
52 results:

  • 1. PELI1: key players in the oncogenic characteristics of pancreatic cancer.
    Fei X; Zhu C; Liu P; Liu S; Ren L; Lu R; Hou J; Gao Y; Wang X; Pan Y
    J Exp Clin Cancer Res; 2024 Mar; 43(1):91. PubMed ID: 38528516
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Identification of mdm2 as a prognostic and immunotherapeutic biomarker in a comprehensive pan-cancer analysis: A promising target for breast cancer, bladder cancer and ovarian cancer immunotherapy.
    Zheng J; Miao F; Wang Z; Ma Y; Lin Z; Chen Y; Kong X; Wang Y; Zhuang A; Wu T; Li W
    Life Sci; 2023 Aug; 327():121832. PubMed ID: 37276911
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Molecular and Functional Heterogeneity of Primary Pancreatic Neuroendocrine Tumors and Metastases.
    Guo Y; Tian C; Cheng Z; Chen R; Li Y; Su F; Shi Y; Tan H
    Neuroendocrinology; 2023; 113(9):943-956. PubMed ID: 37232011
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Enhancement of mdm2 inhibitory effects through blocking nuclear export mechanisms in ovarian cancer cells.
    Alzahrani A; Natarajan U; Rathinavelu A
    Cancer Genet; 2022 Aug; 266-267():57-68. PubMed ID: 35785714
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/mdm2 Inhibitor.
    Lai ZY; Tsai KY; Chang SJ; Chuang YJ
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445495
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Circular RNA S-7 promotes ovarian cancer EMT via sponging miR-641 to up-regulate ZEB1 and mdm2.
    Zhang F; Xu Y; Ye W; Jiang J; Wu C
    Biosci Rep; 2020 Jul; 40(7):. PubMed ID: 32667627
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Holliday junction recognition protein promotes pancreatic cancer growth and metastasis via modulation of the mdm2/p53 signaling.
    Wang CJ; Li X; Shi P; Ding HY; Liu YP; Li T; Lin PP; Wang YS; Zhang GQ; Cao Y
    Cell Death Dis; 2020 May; 11(5):386. PubMed ID: 32439850
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. p53 and mdm2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome.
    Lobo J; Alzamora MA; Guimarães R; Cantante M; Lopes P; Braga I; Maurício J; Jerónimo C; Henrique R
    Andrology; 2020 Sep; 8(5):1233-1242. PubMed ID: 32384200
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Upregulation of circular RNA circ‑FAM53B predicts adverse prognosis and accelerates the progression of ovarian cancer via the miR‑646/VAMP2 and miR‑647/mdm2 signaling pathways.
    Sun D; Liu J; Zhou L
    Oncol Rep; 2019 Dec; 42(6):2728-2737. PubMed ID: 31638250
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. SMYD3 promotes epithelial ovarian cancer metastasis by downregulating p53 protein stability and promoting p53 ubiquitination.
    Zhang L; Jin Y; Yang H; Li Y; Wang C; Shi Y; Wang Y
    Carcinogenesis; 2019 Dec; 40(12):1492-1503. PubMed ID: 31002112
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Targeted Molecular Analysis in Adrenocortical Carcinomas: A Strategy Toward Improved Personalized Prognostication.
    Lippert J; Appenzeller S; Liang R; Sbiera S; Kircher S; Altieri B; Nanda I; Weigand I; Gehrig A; Steinhauer S; Riemens RJM; Rosenwald A; Müller CR; Kroiss M; Rost S; Fassnacht M; Ronchi CL
    J Clin Endocrinol Metab; 2018 Dec; 103(12):4511-4523. PubMed ID: 30113656
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
    Zhang H; Zhang X; Li X; Meng WB; Bai ZT; Rui SZ; Wang ZF; Zhou WC; Jin XD
    J Cell Physiol; 2018 Jan; 234(1):619-631. PubMed ID: 30069972
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals.
    Abrams SL; Lertpiriyapong K; Yang LV; Martelli AM; Cocco L; Ratti S; Falasca M; Murata RM; Rosalen PL; Lombardi P; Libra M; Candido S; Montalto G; Cervello M; Steelman LS; McCubrey JA
    Adv Biol Regul; 2018 Aug; 69():16-34. PubMed ID: 29980405
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. YY1 suppresses proliferation and migration of pancreatic ductal adenocarcinoma by regulating the CDKN3/mdm2/P53/P21 signaling pathway.
    Liu D; Zhang J; Wu Y; Shi G; Yuan H; Lu Z; Zhu Q; Wu P; Lu C; Guo F; Chen J; Jiang K; Miao Y
    Int J Cancer; 2018 Apr; 142(7):1392-1404. PubMed ID: 29168185
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The USP7 Inhibitor P5091 Induces Cell Death in Ovarian cancers with Different P53 Status.
    Wang M; Zhang Y; Wang T; Zhang J; Zhou Z; Sun Y; Wang S; Shi Y; Luan X; Zhang Y; Wang Y; Wang Y; Zou Z; Kang L; Liu H
    Cell Physiol Biochem; 2017; 43(5):1755-1766. PubMed ID: 29049989
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. mdm2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells.
    Chen Y; Wang DD; Wu YP; Su D; Zhou TY; Gai RH; Fu YY; Zheng L; He QJ; Zhu H; Yang B
    Br J Cancer; 2017 Oct; 117(8):1192-1201. PubMed ID: 28817834
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Restoration of p53 using the novel mdm2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.
    Chen H; Luo D; Zhang L; Lin X; Luo Q; Yi H; Wang J; Yan X; Li B; Chen Y; Liu X; Zhang H; Liu S; Qiu M; Yang D; Jiang N
    Oncotarget; 2017 Jun; 8(26):43008-43022. PubMed ID: 28498808
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Cooperation of Musashi-2, Numb, mdm2, and P53 in drug resistance and malignant biology of pancreatic cancer.
    Sheng W; Dong M; Chen C; Wang Z; Li Y; Wang K; Li Y; Zhou J
    FASEB J; 2017 Jun; 31(6):2429-2438. PubMed ID: 28223335
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. mdm2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
    Makii C; Oda K; Ikeda Y; Sone K; Hasegawa K; Uehara Y; Nishijima A; Asada K; Koso T; Fukuda T; Inaba K; Oki S; Machino H; Kojima M; Kashiyama T; Mori-Uchino M; Arimoto T; Wada-Hiraike O; Kawana K; Yano T; Fujiwara K; Aburatani H; Osuga Y; Fujii T
    Oncotarget; 2016 Nov; 7(46):75328-75338. PubMed ID: 27659536
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Testicular germ cell tumor genomics.
    Woldu SL; Amatruda JF; Bagrodia A
    Curr Opin Urol; 2017 Jan; 27(1):41-47. PubMed ID: 27584029
    [TBL] [Abstract] [Full Text] [Related]  


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