BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Clinical Outcome
32 results:

  • 1. Machine learning developed a pi3k/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer.
    Han X; Yang L; Tian H; Ji Y
    Aging (Albany NY); 2023 Oct; 15(20):11162-11183. PubMed ID: 37851341
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Prognostic impact of molecular profiles and molecular signatures in clear cell ovarian cancer.
    Schnack TH; Oliveira DNP; Christiansen AP; Høgdall C; Høgdall E
    Cancer Genet; 2023 Nov; 278-279():9-16. PubMed ID: 37567101
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The Role of Activation of pi3k/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas-New Potential Therapeutic Approach-A Systematic Review.
    Derwich A; Sykutera M; Bromińska B; Rubiś B; Ruchała M; Sawicka-Gutaj N
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446128
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Epigenetic upregulation of MNAT1 by SMYD2 is linked to pi3k/AKT activation and tumorigenesis of pancreatic adenocarcinoma.
    Xu Z; Liu Y; Pan Z; Qin L
    Histol Histopathol; 2024 Feb; 39(2):263-277. PubMed ID: 37232506
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. PTEN Deficiency in Tubo-Ovarian High-Grade Serous Carcinoma is Associated with Poor Progression-Free Survival and is Mutually Exclusive with CCNE1 Amplification.
    Zhang X; Wang A; Han L; Liang B; Allard G; Diver E; Howitt BE
    Mod Pathol; 2023 May; 36(5):100106. PubMed ID: 36805789
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Modulation of intracellular kinase signaling to improve TIL stemness and function for adoptive cell therapy.
    Feng H; Qiu L; Shi Z; Sheng Y; Zhao P; Zhou D; Li F; Yu H; You Y; Wang H; Li M; Zhu S; Du Y; Cui J; Sun J; Liu Y; Jiang H; Wu X
    Cancer Med; 2023 Feb; 12(3):3313-3327. PubMed ID: 36028997
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Comprehensive Analysis of Expression, Prognostic Value, and Immune Infiltration for Ubiquitination-Related FBXOs in Pancreatic Ductal Adenocarcinoma.
    Zhang Y; Liu Q; Cui M; Wang M; Hua S; Gao J; Liao Q
    Front Immunol; 2021; 12():774435. PubMed ID: 35046938
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genetic and epigenetic characterization of posterior pituitary tumors.
    Schmid S; Solomon DA; Perez E; Thieme A; Kleinschmidt-DeMasters BK; Giannini C; Reinhardt A; Asa SL; Mete O; Stichel D; Siewert C; Dittmayer C; Hasselblatt M; Paulus W; Nagel C; Harter PN; Schittenhelm J; Honegger J; Rushing E; Coras R; Pfister SM; Buslei R; Koch A; Perry A; Jones DTW; von Deimling A; Capper D; Lopes MB
    Acta Neuropathol; 2021 Dec; 142(6):1025-1043. PubMed ID: 34661724
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome.
    Hollis RL; Thomson JP; Stanley B; Churchman M; Meynert AM; Rye T; Bartos C; Iida Y; Croy I; Mackean M; Nussey F; Okamoto A; Semple CA; Gourley C; Herrington CS
    Nat Commun; 2020 Oct; 11(1):4995. PubMed ID: 33020491
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Clear cell carcinoma of the ovary: a clinical and molecular perspective.
    Iida Y; Okamoto A; Hollis RL; Gourley C; Herrington CS
    Int J Gynecol Cancer; 2021 Apr; 31(4):605-616. PubMed ID: 32948640
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Distinct gene expression profiles associated with clinical outcomes in patients with ovarian clear cell carcinoma and high-grade serous ovarian carcinoma.
    Zhou H; Liu Q; Shi X; Liu Y; Cao D; Yang J
    J Ovarian Res; 2020 Apr; 13(1):38. PubMed ID: 32295618
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
    Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
    Cancer Lett; 2020 Jan; 469():195-206. PubMed ID: 31672491
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-pi3k/aurora kinase inhibitors.
    Kaipio K; Chen P; Roering P; Huhtinen K; Mikkonen P; Östling P; Lehtinen L; Mansuri N; Korpela T; Potdar S; Hynninen J; Auranen A; Grénman S; Wennerberg K; Hautaniemi S; Carpén O
    J Pathol; 2020 Feb; 250(2):159-169. PubMed ID: 31595974
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Identification of a 4-miRNA signature as a potential prognostic biomarker for pancreatic adenocarcinoma.
    Wang ZX; Deng TX; Ma Z
    J Cell Biochem; 2019 Oct; 120(10):16416-16426. PubMed ID: 31297864
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Genomic Characterization of Testicular Germ Cell Tumors Relapsing After Chemotherapy.
    Necchi A; Bratslavsky G; Corona RJ; Chung JH; Millis SZ; Elvin JA; Vergilio JA; Suh J; Ramkissoon S; Severson E; Daniel S; Killian JK; Ali SM; Schrock AB; Reddy P; Miller VA; Welsh A; Gay LM; Ross JS
    Eur Urol Focus; 2020 Jan; 6(1):122-130. PubMed ID: 30025711
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Randomized, phase I/II study of gemcitabine plus IGF-1R antagonist (MK-0646) versus gemcitabine plus erlotinib with and without MK-0646 for advanced pancreatic adenocarcinoma.
    Abdel-Wahab R; Varadhachary GR; Bhosale PR; Wang X; Fogelman DR; Shroff RT; Overman MJ; Wolff RA; Javle M
    J Hematol Oncol; 2018 May; 11(1):71. PubMed ID: 29843755
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. TLR5/7-mediated pi3k activation triggers epithelial-mesenchymal transition of ovarian cancer cells through WAVE3-dependent mesothelin or OCT4/SOX2 expression.
    Park GB; Kim D
    Oncol Rep; 2017 Nov; 38(5):3167-3176. PubMed ID: 28901470
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. PARP inhibitors alone and in combination with other biological agents in homologous recombination deficient epithelial ovarian cancer: From the basic research to the clinic.
    Gadducci A; Guerrieri ME
    Crit Rev Oncol Hematol; 2017 Jun; 114():153-165. PubMed ID: 28477743
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. CD24 expression is a marker for predicting clinical outcome and regulates the epithelial-mesenchymal transition in ovarian cancer via both the Akt and ERK pathways.
    Nakamura K; Terai Y; Tanabe A; Ono YJ; Hayashi M; Maeda K; Fujiwara S; Ashihara K; Nakamura M; Tanaka Y; Tanaka T; Tsunetoh S; Sasaki H; Ohmichi M
    Oncol Rep; 2017 Jun; 37(6):3189-3200. PubMed ID: 28440503
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Amplification of USP13 drives ovarian cancer metabolism.
    Han C; Yang L; Choi HH; Baddour J; Achreja A; Liu Y; Li Y; Li J; Wan G; Huang C; Ji G; Zhang X; Nagrath D; Lu X
    Nat Commun; 2016 Nov; 7():13525. PubMed ID: 27892457
    [TBL] [Abstract] [Full Text] [Related]  


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