BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND PRKAR1A, DKFZp779L0468, 5573, ENSG00000108946, PRKAR1, P10644, CNC1, PKR1, MGC17251, PPNAD1, TSE1, CNC, CAR
680 results:

  • 1. Mesothelin-based car-T cells exhibit potent antitumor activity against ovarian cancer.
    Guo J; Zeng X; Zhu Y; Yang D; Zhao X
    J Transl Med; 2024 Apr; 22(1):367. PubMed ID: 38637885
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Armored TGFβRIIDN ROR1-car T cells reject solid tumors and resist suppression by constitutively-expressed and treatment-induced TGFβ1.
    Tran TM; Chand Thakuri BK; Nurmukhambetova S; Lee JJ; Hu P; Tran NQ; Steimle B; Dash P; Schneider D
    J Immunother Cancer; 2024 Apr; 12(4):. PubMed ID: 38609317
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Efficient car T cell targeting of the CA125 extracellular repeat domain of MUC16.
    Casey NP; Kleinmanns K; Forcados C; Gelebart PF; Joaquina S; Lode M; Benard E; Kaveh F; Caulier B; Helgestad Gjerde C; García de Jalón E; Warren DJ; Lindemann K; Rokkones E; Davidson B; Myhre MR; Kvalheim G; Bjørge L; McCormack E; Inderberg EM; Wälchli S
    J Immunother Cancer; 2024 Apr; 12(4):. PubMed ID: 38604812
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Complete remission of advanced pancreatic cancer induced by claudin18.2-targeted car-T cell therapy: a case report.
    Zhong G; Zhang X; Guo Z; Gao Y; Zhao B; Liu X; Chen L; Qiao J; Yu C; Wang L; Li Y; Yu L
    Front Immunol; 2024; 15():1325860. PubMed ID: 38487523
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. NK-92MI Cells Engineered with Anti-claudin-6 Chimeric Antigen Receptors in Immunotherapy for Ovarian cancer.
    Li J; Hu H; Lian H; Yang S; Liu M; He J; Cao B; Chen D; Hu Y; Zhi C; Shen Y; Ye X; He B; Zhao M; Fan W; Xu L; Leidner R; Wu Q; Yang L; Zhang Z
    Int J Biol Sci; 2024; 20(5):1578-1601. PubMed ID: 38481806
    [No Abstract]    [Full Text] [Related]  

  • 6. Ectopic CXCR2 expression cells improve the anti-tumor efficiency of car-T cells and remodel the immune microenvironment of pancreatic ductal adenocarcinoma.
    Dai Z; Lin X; Wang X; Zou X; Yan Y; Wang R; Chen Y; Tasiheng Y; Ma M; Wang X; Cheng H; Yu X; Liu C
    Cancer Immunol Immunother; 2024 Mar; 73(4):61. PubMed ID: 38430267
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Mesothelin car T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma.
    Wehrli M; Guinn S; Birocchi F; Kuo A; Sun Y; Larson RC; Almazan AJ; Scarfò I; Bouffard AA; Bailey SR; Anekal PV; Montero Llopis P; Nieman LT; Song Y; Xu KH; Berger TR; Kann MC; Leick MB; Silva H; Salas-Benito D; Kienka T; Grauwet K; Armstrong TD; Zhang R; Zhu Q; Fu J; Schmidts A; Korell F; Jan M; Choi BD; Liss AS; Boland GM; Ting DT; Burkhart RA; Jenkins RW; Zheng L; Jaffee EM; Zimmerman JW; Maus MV
    Clin Cancer Res; 2024 May; 30(9):1859-1877. PubMed ID: 38393682
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Mesothelin antigen density influences anti-mesothelin chimeric antigen receptor T cell cytotoxicity.
    Chu GJ; Bailey CG; Nagarajah R; Liang O; Metierre C; Sagnella SM; Castelletti L; Yeo D; Adelstein S; Rasko JEJ
    Cytotherapy; 2024 Apr; 26(4):325-333. PubMed ID: 38349311
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. New CEACAM-targeting 2A3 single-domain antibody-based chimeric antigen receptor T-cells produce anticancer effects in vitro and in vivo.
    Jancewicz I; Śmiech M; Winiarska M; Zagozdzon R; Wisniewski P
    Cancer Immunol Immunother; 2024 Jan; 73(2):30. PubMed ID: 38279989
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation.
    Lee M; Morris LG
    Oncotarget; 2024 Jan; 15():36-48. PubMed ID: 38275291
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Mucin-1-Targeted Chimeric Antigen Receptor T Cells Are Effective and Safe in Controlling Solid Tumors in Immunocompetent Host.
    Zhou R; Wu ST; Yazdanifar M; Williams C; Sanders A; Brouwer C; Maher J; Mukherjee P
    J Immunother; 2024 Apr; 47(3):77-88. PubMed ID: 38270462
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Immunotherapy for Ovarian cancer: Disappointing or Promising?
    Deng M; Tang F; Chang X; Liu P; Ji X; Hao M; Wang Y; Yang R; Ma Q; Zhang Y; Miao J
    Mol Pharm; 2024 Feb; 21(2):454-466. PubMed ID: 38232985
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Tumor resistance to anti-mesothelin car-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope.
    Liu XF; Onda M; Schlomer J; Bassel L; Kozlov S; Tai CH; Zhou Q; Liu W; Tsao HE; Hassan R; Ho M; Pastan I
    Proc Natl Acad Sci U S A; 2024 Jan; 121(4):e2317283121. PubMed ID: 38227666
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Using Oncolytic Virus to Retask CD19-Chimeric Antigen Receptor T Cells for Treatment of Pancreatic cancer: Toward a Universal Chimeric Antigen Receptor T-Cell Strategy for Solid Tumor.
    Chen C; Park AK; Monroy I; Ren Y; Kim SI; Chaurasiya S; Priceman SJ; Fong Y
    J Am Coll Surg; 2024 Apr; 238(4):436-447. PubMed ID: 38214445
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Chimeric Antigen Receptor T Cell Therapy for Pancreatic cancer: A Review of Current Evidence.
    Czaplicka A; Lachota M; Pączek L; Zagożdżon R; Kaleta B
    Cells; 2024 Jan; 13(1):. PubMed ID: 38201305
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy.
    Horvat NK; Karpovsky I; Phillips M; Wyatt MM; Hall MA; Herting CJ; Hammons J; Mahdi Z; Moffitt RA; Paulos CM; Lesinski GB
    J Immunother Cancer; 2024 Jan; 12(1):. PubMed ID: 38191243
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Molecular characterization of large cell calcifying sertoli cell tumors: A multi-institutional study of 6 benign and 2 malignant tumors.
    Abdulfatah E; Al-Obaidy KI; Robinson D; Wu YM; Heider A; Idrees MT; Ulbright TM; Kunju LP; Wu A
    Hum Pathol; 2024 Feb; 144():15-21. PubMed ID: 38154678
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. car-T cell immunotherapy for ovarian cancer: hushing the silent killer.
    Nasiri F; Farrokhi K; Safarzadeh Kozani P; Mahboubi Kancha M; Dashti Shokoohi S; Safarzadeh Kozani P
    Front Immunol; 2023; 14():1302307. PubMed ID: 38146364
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. [Killing effect of anti-MSLN-icar-NK cells derived from induced pluripotent stem cells on ovarian epithelial cancer cells].
    Fan RJ; Zhang YF; Wang YY; Wang Y; Zheng W
    Zhonghua Fu Chan Ke Za Zhi; 2023 Dec; 58(12):922-929. PubMed ID: 38123198
    [No Abstract]    [Full Text] [Related]  

  • 20. Pyroptosis and the tumor immune microenvironment: A new battlefield in ovarian cancer treatment.
    Wang A; Wang Y; Du C; Yang H; Wang Z; Jin C; Hamblin MR
    Biochim Biophys Acta Rev Cancer; 2024 Mar; 1879(2):189058. PubMed ID: 38113952
    [TBL] [Abstract] [Full Text] [Related]  


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