BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND RAF1, Raf-1, 5894, P04049, ENSG00000132155, c-Raf, CRAF
151 results:

  • 1. Decabromodiphenyl ether exposure reduces dabrafenib sensitivity of papillary thyroid carcinoma harboring BRAF
    Wang X; Cui X; Wang Y; Wang Q; Sun F; Liu Z
    Toxicology; 2024 May; 504():153807. PubMed ID: 38641160
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Disruption of the pro-oncogenic c-raf-PDE8A complex represents a differentiated approach to treating KRAS-c-raf dependent PDAC.
    Cooke SF; Wright TA; Sin YY; Ling J; Kyurkchieva E; Phanthaphol N; Mcskimming T; Herbert K; Rebus S; Biankin AV; Chang DK; Baillie GS; Blair CM
    Sci Rep; 2024 Apr; 14(1):8998. PubMed ID: 38637546
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RNF115 aggravates tumor progression through regulation of CDK10 degradation in thyroid carcinoma.
    Zhu J; Guo L; Dai H; Zheng Z; Yan J; Liu J; Zhang S; Li X; Sun X; Zhao Q; Xu C
    Cell Biol Toxicol; 2024 Feb; 40(1):14. PubMed ID: 38376606
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic cancer Patient-derived Tumors.
    Kazi A; Ranjan A; Kumar M V V; Agianian B; Garcia Chavez M; Vudatha V; Wang R; Vangipurapu R; Chen L; Kennedy P; Subramanian K; Quirke JCK; Beato F; Underwood PW; Fleming JB; Trevino J; Hergenrother PJ; Gavathiotis E; Sebti SM
    Cancer Res Commun; 2023 Dec; 3(12):2623-2639. PubMed ID: 38051103
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy.
    Montenegro MF; Martí-Díaz R; Navarro A; Tolivia J; Sánchez-Del-Campo L; Cabezas-Herrera J; Rodríguez-López JN
    Cell Death Dis; 2023 Nov; 14(11):761. PubMed ID: 37996408
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Characterization of the genomic alterations in poorly differentiated thyroid cancer.
    Lee Y; Moon S; Seok JY; Lee JH; Nam S; Chung YS
    Sci Rep; 2023 Nov; 13(1):19154. PubMed ID: 37932340
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Case report: Complete response of an anaplastic thyroid carcinoma patient with
    Gui L; Zhu Y; Li X; He X; Ma T; Cai Y; Liu S
    Front Immunol; 2023; 14():1178682. PubMed ID: 37122752
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850.
    Spencer KR; Portal DE; Aisner J; Stein MN; Malhotra J; Shih W; Chan N; Silk AW; Ganesan S; Goodin S; Gounder M; Lin H; Li J; Cerchio R; Marinaro C; Chen S; Mehnert JM
    Oncotarget; 2023 Apr; 14():302-315. PubMed ID: 37036756
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway.
    Lan T; Li Y; Wang Y; Wang ZC; Mu CY; Tao AB; Gong JL; Zhou Y; Xu H; Li SB; Gu B; Ma P; Luo L
    Cell Death Dis; 2023 Jan; 14(1):39. PubMed ID: 36653376
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Germline BRCA2 variants in advanced pancreatic acinar cell carcinoma: A case report and review of literature.
    Lee CL; Holter S; Borgida A; Dodd A; Ramotar S; Grant R; Wasson K; Elimova E; Jang RW; Moore M; Kim TK; Khalili K; Moulton CA; Gallinger S; O'Kane GM; Knox JJ
    World J Gastroenterol; 2022 Dec; 28(45):6421-6432. PubMed ID: 36533108
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Role of RAS signaling in ovarian cancer.
    Therachiyil L; Anand A; Azmi A; Bhat A; Korashy HM; Uddin S
    F1000Res; 2022; 11():1253. PubMed ID: 36451660
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. AGAP3: A novel BRAF fusion partner in pediatric pancreatic-type acinar cell carcinoma.
    Paoli C; Burel-Vandenbos F; Coulomb-l'Hermine A; Cros J; Pondrom M; Kubiniek V; Pedeutour F; Dadone-Montaudié B
    Genes Chromosomes Cancer; 2022 Dec; 61(12):734-739. PubMed ID: 35949061
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. RREB1 promotes the development of parafollicular carcinogenesis through the Ras-raf-1-ELK3 signaling pathway.
    Ma S; Wang H; Li W; Yan Z; Luo X; Lu P
    Nucleosides Nucleotides Nucleic Acids; 2022; 41(10):972-981. PubMed ID: 35737446
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. DFMO Improves Survival and Increases Immune Cell Infiltration in Association with MYC Downregulation in the Pancreatic Tumor Microenvironment.
    Nakkina SP; Gitto SB; Beardsley JM; Pandey V; Rohr MW; Parikh JG; Phanstiel O; Altomare DA
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34947972
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Retrospective Case Series Analysis of
    Hendifar A; Blais EM; Wolpin B; Subbiah V; Collisson E; Singh I; Cannon T; Shaw K; Petricoin EF; Klempner S; Lyons E; Wang-Gillam A; Pishvaian MJ; O'Reilly EM
    JCO Precis Oncol; 2021; 5():. PubMed ID: 34476331
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The Association of the BRAF-V600E Mutation with the Expression of the Molecular Markers in the Primary Tumor and Metastatic Tissue in Papillary Thyroid cancer.
    Spirina LV; Chizhevskaya SY; Kovaleva IV; Kondakova IV
    Asian Pac J Cancer Prev; 2021 Jul; 22(7):2017-2024. PubMed ID: 34319022
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors.
    Dobrovolskaite A; Madan M; Pandey V; Altomare DA; Phanstiel O
    Int J Biochem Cell Biol; 2021 Sep; 138():106038. PubMed ID: 34252566
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. LncRNA CERS6-AS1 promotes proliferation and metastasis through the upregulation of YWHAG and activation of ERK signaling in pancreatic cancer.
    Xu J; Wang J; He Z; Chen P; Jiang X; Chen Y; Liu X; Jiang J
    Cell Death Dis; 2021 Jun; 12(7):648. PubMed ID: 34168120
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Characteristics of ovarian malignancy in Bali province, Indonesia.
    Budiana ING; Prayudi PKA; Saspriyana KY; Darmayasa IM; Wiradnyana AAG; Suwiyoga K
    Med J Malaysia; 2021 May; 76(3):326-331. PubMed ID: 34031330
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in Pancreatic Acinar Cells.
    Assi M; Achouri Y; Loriot A; Dauguet N; Dahou H; Baldan J; Libert M; Fain JS; Guerra C; Bouwens L; Barbacid M; Lemaigre FP; Jacquemin P
    Cancer Res; 2021 May; 81(10):2679-2689. PubMed ID: 33602788
    [TBL] [Abstract] [Full Text] [Related]  


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