BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Endocrine gland cancer AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS AND Prognosis
21 results:

  • 1. Adjuvant mitotane versus surveillance in low-grade, localised adrenocortical carcinoma (ADIUVO): an international, multicentre, open-label, randomised, phase 3 trial and observational study.
    Terzolo M; Fassnacht M; Perotti P; Libé R; Kastelan D; Lacroix A; Arlt W; Haak HR; Loli P; Decoudier B; Lasolle H; Quinkler M; Haissaguerre M; Chabre O; Caron P; Stigliano A; Giordano R; Zatelli MC; Bancos I; Fragoso MCBV; Canu L; Luconi M; Puglisi S; Basile V; Reimondo G; Kroiss M; Megerle F; Hahner S; Kimpel O; Dusek T; Nölting S; Bourdeau I; Chortis V; Ettaieb MH; Cosentini D; Grisanti S; Baudin E; Berchialla P; Bovis F; Sormani MP; Bruzzi P; Beuschlein F; Bertherat J; Berruti A
    Lancet Diabetes Endocrinol; 2023 Oct; 11(10):720-730. PubMed ID: 37619579
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The metabolic stress-activated checkpoint lkb1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma.
    Machino H; Kaneko S; Komatsu M; Ikawa N; Asada K; Nakato R; Shozu K; Dozen A; Sone K; Yoshida H; Kato T; Oda K; Osuga Y; Fujii T; von Keudell G; Saloura V; Hamamoto R
    Commun Biol; 2022 Jan; 5(1):39. PubMed ID: 35017636
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Hereditary pancreatic cancer.
    Abe K; Kitago M; Kitagawa Y; Hirasawa A
    Int J Clin Oncol; 2021 Oct; 26(10):1784-1792. PubMed ID: 34476650
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. [Molecular predictors for the course of disease and individualized therapy in pancreatic cancer].
    Damanakis AI; Gebauer F; Bruns CJ
    Chirurg; 2020 Aug; 91(8):642-649. PubMed ID: 32405728
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Risk Stratification Using a Novel Genetic Classifier Including
    Jung CK; Jung SH; Jeon S; Jeong YM; Kim Y; Lee S; Bae JS; Chung YJ
    Thyroid; 2020 Nov; 30(11):1589-1600. PubMed ID: 32326836
    [No Abstract]    [Full Text] [Related]  

  • 6. Establishment and characterization of a new patient-derived anaplastic thyroid cancer cell line (C3948), obtained through fine-needle aspiration cytology.
    Pinto AT; Pojo M; Simões-Pereira J; Roque R; Saramago A; Roque L; Martins C; André S; Cabeçadas J; Leite V; Cavaco BM
    Endocrine; 2019 Nov; 66(2):288-300. PubMed ID: 31368081
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Epidemiology and risk factors of pancreatic cancer.
    Capasso M; Franceschi M; Rodriguez-Castro KI; Crafa P; Cambiè G; Miraglia C; Barchi A; Nouvenne A; Leandro G; Meschi T; De' Angelis GL; Di Mario F
    Acta Biomed; 2018 Dec; 89(9-S):141-146. PubMed ID: 30561407
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integrated Genomic and Immunophenotypic Classification of Pancreatic cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance.
    Wartenberg M; Cibin S; Zlobec I; Vassella E; Eppenberger-Castori S; Terracciano L; Eichmann MD; Worni M; Gloor B; Perren A; Karamitopoulou E
    Clin Cancer Res; 2018 Sep; 24(18):4444-4454. PubMed ID: 29661773
    [No Abstract]    [Full Text] [Related]  

  • 9. Construction of a prognostic prediction system for pancreatic ductal adenocarcinoma to investigate the key prognostic genes.
    Zheng B; Peng J; Mollayup A; Bakri A; Guo L; Zheng J; Xu H
    Mol Med Rep; 2018 Jan; 17(1):216-224. PubMed ID: 29115420
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma.
    Kumazoe M; Takai M; Hiroi S; Takeuchi C; Kadomatsu M; Nojiri T; Onda H; Bae J; Huang Y; Takamatsu K; Yamashita S; Kangawa K; Tachibana H
    J Biol Chem; 2017 Jun; 292(26):10813-10823. PubMed ID: 28507102
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Updates and Critical Evaluation on Novel Biomarkers for the Malignant Progression of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
    Moris D; Damaskos C; Spartalis E; Papalampros A; Vernadakis S; Dimitroulis D; Griniatsos J; Felekouras E; Nikiteas N
    Anticancer Res; 2017 May; 37(5):2185-2194. PubMed ID: 28476781
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Widely metastatic atypical pituitary adenoma with mTOR pathway stk11(F298L) mutation treated with everolimus therapy.
    Donovan LE; Arnal AV; Wang SH; Odia Y
    CNS Oncol; 2016 Oct; 5(4):203-9. PubMed ID: 27615706
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of lkb1 and activation of AMPK in PDACs.
    Cheng X; Kim JY; Ghafoory S; Duvaci T; Rafiee R; Theobald J; Alborzinia H; Holenya P; Fredebohm J; Merz KH; Mehrabi A; Hafezi M; Saffari A; Eisenbrand G; Hoheisel JD; Wölfl S
    Mol Oncol; 2016 Jun; 10(6):806-24. PubMed ID: 26887594
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Metformin and pancreatic cancer: Is there a role?
    De Souza A; Khawaja KI; Masud F; Saif MW
    Cancer Chemother Pharmacol; 2016 Feb; 77(2):235-42. PubMed ID: 26740120
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Decreased lkb1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma.
    Yang JY; Jiang SH; Liu DJ; Yang XM; Huo YM; Li J; Hua R; Zhang ZG; Sun YW
    Sci Rep; 2015 May; 5():10575. PubMed ID: 26015068
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Management and prognosis of patients with ovarian sex cord tumor with annular tubules: a retrospective study.
    Qian Q; You Y; Yang J; Cao D; Zhu Z; Wu M; Chen J; Lang J; Shen K
    BMC Cancer; 2015 Apr; 15():270. PubMed ID: 25886261
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Loss of lkb1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.
    Tanwar PS; Mohapatra G; Chiang S; Engler DA; Zhang L; Kaneko-Tarui T; Ohguchi Y; Birrer MJ; Teixeira JM
    Carcinogenesis; 2014 Mar; 35(3):546-53. PubMed ID: 24170201
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Contribution of CXCR4 and SMAD4 in predicting disease progression pattern and benefit from adjuvant chemotherapy in resected pancreatic adenocarcinoma.
    Bachet JB; Maréchal R; Demetter P; Bonnetain F; Couvelard A; Svrcek M; Bardier-Dupas A; Hammel P; Sauvanet A; Louvet C; Paye F; Rougier P; Penna C; Vaillant JC; André T; Closset J; Salmon I; Emile JF; Van Laethem JL
    Ann Oncol; 2012 Sep; 23(9):2327-2335. PubMed ID: 22377565
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. lkb1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.
    Morton JP; Jamieson NB; Karim SA; Athineos D; Ridgway RA; Nixon C; McKay CJ; Carter R; Brunton VG; Frame MC; Ashworth A; Oien KA; Evans TR; Sansom OJ
    Gastroenterology; 2010 Aug; 139(2):586-97, 597.e1-6. PubMed ID: 20452353
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Clinical genetics of multiple endocrine neoplasias, Carney complex and related syndromes.
    Stratakis CA
    J Endocrinol Invest; 2001 May; 24(5):370-83. PubMed ID: 11407658
    [TBL] [Abstract] [Full Text] [Related]  


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