BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Gastric cancer AND FGFR2, BFR-1, 2263, ENSG00000066468, TK14, BEK, CD332, JWS, TK25, ECT1, CEK3, K-SAM, CFD1, KGFR
234 results:

  • 1. A Phase I Study of KIN-3248, an Irreversible Small-molecule Pan-FGFR Inhibitor, in Patients with Advanced fgfr2/3-driven Solid Tumors.
    Garmezy B; Borad MJ; Bahleda R; Perez CA; Chen LT; Kato S; Oh DY; Severson P; Tam BY; Quah CS; Harding JJ
    Cancer Res Commun; 2024 Apr; 4(4):1165-1173. PubMed ID: 38602417
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Advances in targeted therapy for gastric cancer based on tumor driver genes.
    Wu S; Xu P; Zhang F
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2023 Feb; 53(1):73-83. PubMed ID: 38413217
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Investigating fgfr2 gene as a blood-based epigenetic biomarker in gastric cancer.
    Aleyasin SA; Moradi A; Abolhasani N; Abdollahi M
    Mol Biol Rep; 2024 Feb; 51(1):253. PubMed ID: 38302798
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Identification of Potential Genomic Alterations Using Pan-cancer Cell-Free DNA Next-Generation Sequencing in Patients With gastric cancer.
    Kim B; Kim Y; Cho JY; Lee KA
    Ann Lab Med; 2024 Mar; 44(2):164-173. PubMed ID: 37903652
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression.
    Huang YC; Chen WC; Yu CL; Chang TK; I-Chin Wei A; Chang TM; Liu JF; Wang SW
    Biochem Pharmacol; 2023 Dec; 218():115853. PubMed ID: 37832794
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. MDM2 amplification is rare in gastric cancer.
    Abdullazade S; Behrens HM; Krüger S; Haag J; Röcken C
    Virchows Arch; 2023 Dec; 483(6):795-807. PubMed ID: 37821635
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Targeting FGFRs by pemigatinib induces G1 phase cell cycle arrest, cellular stress and upregulation of tumor suppressor microRNAs.
    Pace A; Scirocchi F; Napoletano C; Zizzari IG; Po A; Megiorni F; Asquino A; Pontecorvi P; Rahimi H; Marchese C; Ferretti E; Nuti M; Rughetti A
    J Transl Med; 2023 Sep; 21(1):626. PubMed ID: 37715207
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Futibatinib, an Irreversible FGFR1-4 Inhibitor for the Treatment of FGFR-Aberrant Tumors.
    Javle M; King G; Spencer K; Borad MJ
    Oncologist; 2023 Nov; 28(11):928-943. PubMed ID: 37390492
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Oncogenic structural aberration landscape in gastric cancer genomes.
    Saito-Adachi M; Hama N; Totoki Y; Nakamura H; Arai Y; Hosoda F; Rokutan H; Yachida S; Kato M; Fukagawa A; Shibata T
    Nat Commun; 2023 Jun; 14(1):3688. PubMed ID: 37349325
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. [Study of fgfr2 status in gastric cancer by immunohistochemistry and fluorescent in situ hybridization].
    Raskin GA; Mukhina MS; Kravtsova ED; Tsimafeyeu IV; Tyulandin SA; Belyak NP; Kleshchev MA; Orlova RV
    Arkh Patol; 2023; 85(3):40-45. PubMed ID: 37272439
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Discovery of a Selective and Orally Bioavailable fgfr2 Degrader for Treating gastric cancer.
    Ma L; Li Y; Luo R; Wang Y; Cao J; Fu W; Qian B; Zheng L; Tang L; Lv X; Zheng L; Liang G; Chen L
    J Med Chem; 2023 Jun; 66(11):7438-7453. PubMed ID: 37220310
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The Emerging Role of Circulating Tumor DNA in Non-Colorectal Gastrointestinal cancers.
    Lee MS; Kaseb AO; Pant S
    Clin Cancer Res; 2023 Sep; 29(17):3267-3274. PubMed ID: 37092904
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Decoding the Conformational Selective Mechanism of FGFR Isoforms: A Comparative Molecular Dynamics Simulation.
    Zhang M; Yasen M; Lu S; Ma DN; Chai Z
    Molecules; 2023 Mar; 28(6):. PubMed ID: 36985681
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A phase 1b study of the allosteric extracellular fgfr2 inhibitor alofanib in patients with pretreated advanced gastric cancer.
    Tsimafeyeu I; Statsenko G; Vladimirova L; Besova N; Artamonova E; Raskin G; Rykov I; Mochalova A; Utyashev I; Gorbacheva S; Kazey V; Gavrilova E; Dragun N; Moiseyenko V; Tjulandin S
    Invest New Drugs; 2023 Apr; 41(2):324-332. PubMed ID: 36907947
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Comparative Meta-analysis of Adipose Tissue Transcriptomics Data in PCOS Patients and Healthy Control Women.
    Saedi S; Panahi R; Orak N; Jafarzadeh Shirazi MR
    Reprod Sci; 2023 Jun; 30(6):1823-1833. PubMed ID: 36512189
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Futibatinib: First Approval.
    Syed YY
    Drugs; 2022 Dec; 82(18):1737-1743. PubMed ID: 36441501
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. fgfr2-amplified tumor clones are markedly heterogeneously distributed in carcinomas of the upper gastrointestinal tract.
    Albin J; Fahrig L; Siemanowski J; Rehkaemper J; Gebauer F; Zander T; Buettner R; Bruns CJ; Schroeder W; Alakus H; Hieggelke L; Quaas A
    J Cancer Res Clin Oncol; 2023 Jul; 149(8):5289-5300. PubMed ID: 36416959
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. [Oesogastric cancer - new therapeutic targets].
    Palmieri LJ; Soubeyran I; Pernot S
    Bull Cancer; 2023 May; 110(5):560-569. PubMed ID: 36371284
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Somatic ARID1A mutation stratifies patients with gastric cancer to PD-1 blockade and adjuvant chemotherapy.
    Gu Y; Zhang P; Wang J; Lin C; Liu H; Li H; He H; Li R; Zhang H; Zhang W
    Cancer Immunol Immunother; 2023 May; 72(5):1199-1208. PubMed ID: 36369379
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Clinical and molecular characteristics of kinase domain duplications across diverse cancer types in the Chinese population.
    Lai X; Yu R; Ou Q; Bao H; Wu X; Shao Y; Li Y; Zhang Y; Ding Q
    Cancer Med; 2023 Mar; 12(5):6009-6015. PubMed ID: 36325957
    [TBL] [Abstract] [Full Text] [Related]  


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