Terms: = Gastric cancer AND FGFR2, BFR-1, 2263, ENSG00000066468, TK14, BEK, CD332, JWS, TK25, ECT1, CEK3, K-SAM, CFD1, KGFR AND Treatment
79 results:
1. A Phase I Study of KIN-3248, an Irreversible Small-molecule Pan-FGFR Inhibitor, in Patients with Advanced fgfr2/3-driven Solid Tumors.
Garmezy B; Borad MJ; Bahleda R; Perez CA; Chen LT; Kato S; Oh DY; Severson P; Tam BY; Quah CS; Harding JJ
Cancer Res Commun; 2024 Apr; 4(4):1165-1173. PubMed ID: 38602417
[TBL] [Abstract] [Full Text] [Related]
2. Advances in targeted therapy for gastric cancer based on tumor driver genes.
Wu S; Xu P; Zhang F
Zhejiang Da Xue Xue Bao Yi Xue Ban; 2023 Feb; 53(1):73-83. PubMed ID: 38413217
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3. Identification of Potential Genomic Alterations Using Pan-cancer Cell-Free DNA Next-Generation Sequencing in Patients With gastric cancer.
Kim B; Kim Y; Cho JY; Lee KA
Ann Lab Med; 2024 Mar; 44(2):164-173. PubMed ID: 37903652
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4. FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression.
Huang YC; Chen WC; Yu CL; Chang TK; I-Chin Wei A; Chang TM; Liu JF; Wang SW
Biochem Pharmacol; 2023 Dec; 218():115853. PubMed ID: 37832794
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5. Targeting FGFRs by pemigatinib induces G1 phase cell cycle arrest, cellular stress and upregulation of tumor suppressor microRNAs.
Pace A; Scirocchi F; Napoletano C; Zizzari IG; Po A; Megiorni F; Asquino A; Pontecorvi P; Rahimi H; Marchese C; Ferretti E; Nuti M; Rughetti A
J Transl Med; 2023 Sep; 21(1):626. PubMed ID: 37715207
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6. Futibatinib, an Irreversible FGFR1-4 Inhibitor for the treatment of FGFR-Aberrant Tumors.
Javle M; King G; Spencer K; Borad MJ
Oncologist; 2023 Nov; 28(11):928-943. PubMed ID: 37390492
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7. [Study of fgfr2 status in gastric cancer by immunohistochemistry and fluorescent in situ hybridization].
Raskin GA; Mukhina MS; Kravtsova ED; Tsimafeyeu IV; Tyulandin SA; Belyak NP; Kleshchev MA; Orlova RV
Arkh Patol; 2023; 85(3):40-45. PubMed ID: 37272439
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8. The Emerging Role of Circulating Tumor DNA in Non-Colorectal Gastrointestinal cancers.
Lee MS; Kaseb AO; Pant S
Clin Cancer Res; 2023 Sep; 29(17):3267-3274. PubMed ID: 37092904
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9. A phase 1b study of the allosteric extracellular fgfr2 inhibitor alofanib in patients with pretreated advanced gastric cancer.
Tsimafeyeu I; Statsenko G; Vladimirova L; Besova N; Artamonova E; Raskin G; Rykov I; Mochalova A; Utyashev I; Gorbacheva S; Kazey V; Gavrilova E; Dragun N; Moiseyenko V; Tjulandin S
Invest New Drugs; 2023 Apr; 41(2):324-332. PubMed ID: 36907947
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10. Futibatinib: First Approval.
Syed YY
Drugs; 2022 Dec; 82(18):1737-1743. PubMed ID: 36441501
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11. fgfr2-amplified tumor clones are markedly heterogeneously distributed in carcinomas of the upper gastrointestinal tract.
Albin J; Fahrig L; Siemanowski J; Rehkaemper J; Gebauer F; Zander T; Buettner R; Bruns CJ; Schroeder W; Alakus H; Hieggelke L; Quaas A
J Cancer Res Clin Oncol; 2023 Jul; 149(8):5289-5300. PubMed ID: 36416959
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12. Clinical and molecular characteristics of kinase domain duplications across diverse cancer types in the Chinese population.
Lai X; Yu R; Ou Q; Bao H; Wu X; Shao Y; Li Y; Zhang Y; Ding Q
Cancer Med; 2023 Mar; 12(5):6009-6015. PubMed ID: 36325957
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13. Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy.
Patrad E; Khalighfard S; Amiriani T; Khori V; Alizadeh AM
Cell Oncol (Dordr); 2022 Dec; 45(6):1073-1117. PubMed ID: 36149600
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14. Identification and characterization of fgfr2
Qiu H; Zhang X; Qi J; Zhang J; Tong Y; Li L; Fu L; Qin YR; Guan X; Zhang L
J Exp Clin Cancer Res; 2022 Aug; 41(1):240. PubMed ID: 35941662
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15. gastric carcinosarcoma with fgfr2 amplification under long-term control with pazopanib: a case report and literature review.
Hayashi H; Makiyama A; Okumura N; Yasufuku I; Saigo C; Takeuchi T; Miyazaki T; Tanaka Y; Matsuhashi N; Murase K; Takahashi T; Futamura M; Yoshida K
BMC Gastroenterol; 2022 Jul; 22(1):360. PubMed ID: 35902814
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16. Anlotinib Combined with Toripalimab as Second-Line Therapy for Advanced, Relapsed gastric or Gastroesophageal Junction Carcinoma.
Jiang M; Zhang C; Hu Y; Li T; Yang G; Wang G; Zhu J; Shao C; Hou H; Zhou N; Liu K; Zhang X
Oncologist; 2022 Nov; 27(11):e856-e869. PubMed ID: 35857405
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17. mTOR pathway gene mutations predict response to immune checkpoint inhibitors in multiple cancers.
Cheng L; Wang Y; Qiu L; Chang Y; Lu H; Liu C; Zhang B; Zhou Y; Bai H; Xiong L; Zhong H; Nie W; Han B
J Transl Med; 2022 May; 20(1):247. PubMed ID: 35642038
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18. Efficacy and safety of combination chemotherapy regimens containing taxanes for first-line treatment in advanced gastric cancer.
Ma X; Zhang Y; Wang C; Yu J
Clin Exp Med; 2023 Jun; 23(2):381-396. PubMed ID: 35428957
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19. Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer.
Shirakihara T; Yamaguchi H; Kondo T; Yashiro M; Sakai R
Oncogene; 2022 Apr; 41(18):2587-2596. PubMed ID: 35338344
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20. Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.
Kleo K; Jovanovic VM; Arndold A; Lehmann A; Lammert H; Berg E; Harloff H; Treese C; Hummel M; Daum S
J Cancer Res Clin Oncol; 2023 Mar; 149(3):1049-1061. PubMed ID: 35246724
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