Terms: = Gastric cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1
90 results:
1. Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction.
Weidner P; Saar D; Söhn M; Schroeder T; Yu Y; Zöllner FG; Ponelies N; Zhou X; Zwicky A; Rohrbacher FN; Pattabiraman VR; Tanriver M; Bauer A; Ahmed H; Ametamey SM; Riffel P; Seger R; Bode JW; Wade RC; Ebert MPA; Kragelund BB; Burgermeister E
Cancer Lett; 2024 Apr; 588():216783. PubMed ID: 38462034
[TBL] [Abstract] [Full Text] [Related]
2. Ceramide promotes lytic reactivation of Epstein-Barr virus in gastric carcinoma.
Kim JY; Min YJ; Lee M-H; An YR; Ashktorab H; Smoot DT; Kwon SW; Lee SK
J Virol; 2024 Feb; 98(2):e0177623. PubMed ID: 38197630
[TBL] [Abstract] [Full Text] [Related]
3. High In Vitro and In Vivo Activity of BI-847325, a Dual MEK/Aurora Kinase Inhibitor, in Human Solid and Hematologic cancer Models.
Vuaroqueaux V; Musch A; Peille AL; Kelter G; Weichert L; Metz T; Hendriks HR; Fiebig HH
Cancer Res Commun; 2023 Oct; 3(10):2170-2181. PubMed ID: 37830744
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4. Exploring the Potential Mechanism of Action of Ursolic Acid against gastric cancer and COVID-19 using Network Pharmacology and Bioinformatics Analysis.
Liu Z; Huang H; Yu Y; Jia Y; Li L; Shi X; Wang F
Curr Pharm Des; 2023; 29(16):1274-1292. PubMed ID: 37218202
[TBL] [Abstract] [Full Text] [Related]
5. Driver and targetable alterations in Chinese patients with small bowel carcinoma.
Li J; Li X; Dong N; Yan S; Jing C; Ma T; Li W; Zhang C; Cai Y; Deng W
J Cancer Res Clin Oncol; 2023 Aug; 149(9):6139-6150. PubMed ID: 36680582
[TBL] [Abstract] [Full Text] [Related]
6. Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex.
Wang X; Xie Q; Ji Y; Yang J; Shen J; Peng F; Zhang Y; Jiang F; Kong X; Ma W; Liu D; Zheng L; Qing C; Lang JY
Cell Rep; 2023 Jan; 42(1):111972. PubMed ID: 36641751
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7. CHD4 promotes acquired chemoresistance and tumor progression by activating the MEK/ERK axis.
Wu J; Zhou Z; Li J; Liu H; Zhang H; Zhang J; Huang W; He Y; Zhu S; Huo M; Liu M; Zhang C
Drug Resist Updat; 2023 Jan; 66():100913. PubMed ID: 36603431
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8. A synergistic partnership between IL-33/ST2 and Wnt pathway through Bcl-xL drives gastric cancer stemness and metastasis.
Kwon JW; Seok SH; Kim S; An HW; Choudhury AD; Woo SH; Oh JS; Kim JK; Voon DC; Kim DY; Park JW
Oncogene; 2023 Feb; 42(7):501-515. PubMed ID: 36526851
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9. Epstein-Barr Virus Regulates Endothelin-1 Expression through the ERK/FOXO1 Pathway in EBV-Associated gastric cancer.
Liu W; Zhang Q; Zhang Y; Sun L; Xiao H; Luo B
Microbiol Spectr; 2023 Feb; 11(1):e0089822. PubMed ID: 36475746
[TBL] [Abstract] [Full Text] [Related]
10. MicroRNA-34c-5p exhibits anticancer properties in gastric cancer by targeting map2k1 to inhibit cell proliferation, migration, and invasion.
Ma Q; Zhao Y; Li Z; Gao W; Xu Y; Li B; Huang Y; Huo Z
Biomed Res Int; 2022; 2022():7375661. PubMed ID: 36203485
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11. Prognostic Value, Immune Signature, and Molecular Mechanisms of the PHLDA Family in Pancreatic Adenocarcinoma.
Duan Y; Du Y; Gu Z; Zheng X; Wang C
Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142223
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12. Elevated Notch-1 expression promotes the lymph node metastasis of gastric cancer and the Notch-1-PTEN-ERK1/2 signalling axis promotes the progression of gastric cancer.
Ma H; Li N; Mo Z
Cytokine; 2022 Nov; 159():156013. PubMed ID: 36067712
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13. Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-
Yu GX; Hu Y; Zhang WX; Tian XY; Zhang SY; Zhang Y; Yuan S; Song J
Molecules; 2022 Aug; 27(15):. PubMed ID: 35956943
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14. Inhibition of LPS-mediated TLR4 activation abrogates gastric adenocarcinoma-associated peritoneal metastasis.
Sangwan V; Al-Marzouki L; Pal S; Stavrakos V; Alzahrani M; Antonatos D; Nevo Y; Camilleri-Broët S; Rayes R; Bourdeau F; Giannias B; Bertos N; Bailey S; Rousseau S; Cools-Lartigue J; Spicer JD; Ferri L
Clin Exp Metastasis; 2022 Apr; 39(2):323-333. PubMed ID: 34767138
[TBL] [Abstract] [Full Text] [Related]
15. Integrative pan-cancer analysis of mek1 aberrations and the potential clinical implications.
Zhou Z; Peng B; Li J; Gao K; Cai Y; Xu Z; Yan Y
Sci Rep; 2021 Sep; 11(1):18366. PubMed ID: 34526571
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16. Hyperactivation of MEK/ERK pathway by Ca
Najar MA; Aravind A; Dagamajalu S; Sidransky D; Ashktorab H; Smoot DT; Gowda H; Prasad TSK; Modi PK; Chatterjee A
Mol Carcinog; 2021 Nov; 60(11):769-783. PubMed ID: 34437731
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17. mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via mek1-ERKs and BMP-Smad1 pathways.
Li K; Wu H; Wang A; Charron J; Mishina Y; Habib SL; Liu H; Li B
Cell Rep; 2021 May; 35(5):109069. PubMed ID: 33951440
[TBL] [Abstract] [Full Text] [Related]
18. Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer.
Mezynski MJ; Farrelly AM; Cremona M; Carr A; Morgan C; Workman J; Armstrong P; McAuley J; Madden S; Fay J; Sheehan KM; Kay EW; Holohan C; Elamin Y; Rafee S; Morris PG; Breathnach O; Grogan L; Hennessy BT; Toomey S
J Transl Med; 2021 May; 19(1):184. PubMed ID: 33933113
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19. A novel protein encoded by circMAPK1 inhibits progression of gastric cancer by suppressing activation of MAPK signaling.
Jiang T; Xia Y; Lv J; Li B; Li Y; Wang S; Xuan Z; Xie L; Qiu S; He Z; Wang L; Xu Z
Mol Cancer; 2021 Apr; 20(1):66. PubMed ID: 33836754
[TBL] [Abstract] [Full Text] [Related]
20. p-MEK expression predicts prognosis of patients with adenocarcinoma of esophagogastric junction (AEG) and plays a role in anti-AEG efficacy of Huaier.
Yuan L; Mo SW; Xu ZY; Lv H; Xu JL; Guo KB; Hu C; Wang XF; Chen GP; Qin JJ; Cheng XD
Pharmacol Res; 2021 Mar; 165():105411. PubMed ID: 33401002
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