Terms: = Gastric cancer AND NFE2L2, ENSG00000116044, 4780, Q16236, NRF2 AND Treatment
35 results:
1. Nortriptyline hydrochloride, a potential candidate for drug repurposing, inhibits gastric cancer by inducing oxidative stress by triggering the Keap1-nrf2 pathway.
Zhu C; Lu Y; Wang S; Song J; Ding Y; Wang Y; Dong C; Liu J; Qiu W; Qi W
Sci Rep; 2024 Mar; 14(1):6050. PubMed ID: 38480798
[TBL] [Abstract] [Full Text] [Related]
2. Acyltransferase zinc finger DHHC-type containing 2 aggravates gastric carcinoma growth by targeting nrf2 signaling: A mechanism-based multicombination bionic nano-drug therapy.
Liu L; Wang L; Liu L; Qu X; Zhao W; Ding J; Zhao S; Xu B; Yu H; Liu B; Chai J
Redox Biol; 2024 Apr; 70():103051. PubMed ID: 38301594
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3. Proapoptotic effect of WS-299 induced by NOXA accumulation and nrf2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers.
Ma T; Song Q; Cheng B; Guo E; Wang X; Li M; Dai M; Li S; Feng S; Yu B
Bioorg Chem; 2024 Mar; 144():107142. PubMed ID: 38280358
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4.
Kong W; Liu X; Zhu H; Zheng S; Yin G; Yu P; Shan Y; Ma S; Ying R; Jin H
Aging (Albany NY); 2024 Jan; 16(2):1767-1780. PubMed ID: 38244583
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5. Natural products for gastric carcinoma prevention and treatment: Focus on their antioxidant stress actions in the Correa's cascade.
Guo C; Wan L; Li C; Wen Y; Pan H; Zhao M; Wang J; Ma X; Nian Q; Tang J; Zeng J
Phytomedicine; 2024 Jan; 123():155253. PubMed ID: 38065034
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6. Yi-qi-hua-yu-jie-du decoction induces ferroptosis in cisplatin-resistant gastric cancer via the AKT/GSK3β/nrf2/GPX4 axis.
Huang W; Wen F; Yang P; Li Y; Li Q; Shu P
Phytomedicine; 2024 Jan; 123():155220. PubMed ID: 38056149
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7. Heterogeneity of Phase II Enzyme Ligands on Controlling the Progression of Human gastric cancer Organoids as Stem Cell Therapy Model.
Wu DC; Ku CC; Pan JB; Wuputra K; Yang YH; Liu CJ; Liu YC; Kato K; Saito S; Lin YC; Chong IW; Hsiao M; Hu HM; Kuo CH; Kuo KK; Lin CS; Yokoyama KK
Int J Mol Sci; 2023 Nov; 24(21):. PubMed ID: 37958895
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8. ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis.
Yang Z; Zou S; Zhang Y; Zhang J; Zhang P; Xiao L; Xie Y; Meng M; Feng J; Kang L; Lee MH; Fang L
Nat Commun; 2023 Jul; 14(1):4193. PubMed ID: 37443154
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9. Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
Wang C; Dai S; Zhao X; Zhang Y; Gong L; Fu K; Ma C; Peng C; Li Y
Biomed Pharmacother; 2023 Jul; 163():114882. PubMed ID: 37196541
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10. CHFR promotes metastasis of human gastric carcinoma by activating AKT and ERK via nrf2- ROS axis.
He F; Ye B; Wu X; Pan J; Wang J; Wang X
BMC Gastroenterol; 2023 Apr; 23(1):114. PubMed ID: 37024798
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11. Diclofenac Sensitizes Signet Ring Cell gastric Carcinoma Cells to Cisplatin by Activating Autophagy and Inhibition of Survival Signal Pathways.
Lae Lae Phoo N; Sukhamwang A; Dejkriengkraikul P; Yodkeeree S
Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36292923
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12. Suppression of JNK/ERK dependent autophagy enhances Jaspine B derivative-induced gastric cancer cell death via attenuation of p62/Keap1/nrf2 pathways.
Xu F; Xie Q; Li YW; Jing QQ; Liu XJ; Xu YC; Wang X; Liu L; Kim G; Choi Y; Guo Y; Zhang E; Jin CY
Toxicol Appl Pharmacol; 2022 Mar; 438():115908. PubMed ID: 35123989
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13. Discovery of a cinnamyl piperidine derivative as new neddylation inhibitor for gastric cancer treatment.
Wang B; Zhang QH; Li XJ; Wang SQ; Chen XB; Yu B; Liu HM
Eur J Med Chem; 2021 Dec; 226():113896. PubMed ID: 34624825
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14. Propofol suppresses cell proliferation in gastric cancer cells through nrf2-mediated polyol pathway.
Cao Y; Fan L; Li L; Zhou J
Clin Exp Pharmacol Physiol; 2022 Feb; 49(2):264-274. PubMed ID: 34570396
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15. Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining nrf2/Keap1/xCT signaling.
Fu D; Wang C; Yu L; Yu R
Cell Mol Biol Lett; 2021 Jun; 26(1):26. PubMed ID: 34098867
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16. Potential of Sulforaphane as a Natural Immune System Enhancer: A Review.
Mahn A; Castillo A
Molecules; 2021 Feb; 26(3):. PubMed ID: 33535560
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17. UFBP1, a key component in ufmylation, enhances drug sensitivity by promoting proteasomal degradation of oxidative stress-response transcription factor nrf2.
Hu Z; Wang X; Li D; Cao L; Cui H; Xu G
Oncogene; 2021 Jan; 40(3):647-662. PubMed ID: 33219317
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18. nrf2 Inhibitor, Brusatol in Combination with Trastuzumab Exerts Synergistic Antitumor Activity in HER2-Positive cancers by Inhibiting nrf2/HO-1 and HER2-AKT/ERK1/2 Pathways.
Yang Y; Tian Z; Guo R; Ren F
Oxid Med Cell Longev; 2020; 2020():9867595. PubMed ID: 32765809
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19. iASPP-Mediated ROS Inhibition Drives 5-Fu Resistance Dependent on nrf2 Antioxidative Signaling Pathway in gastric Adenocarcinoma.
Wen L; Yang S; Li P; Chen R; Wang Q; Kaspo B; Fan H; Hu J
Dig Dis Sci; 2020 Oct; 65(10):2873-2883. PubMed ID: 31938994
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20. Schisantherin A induces cell apoptosis through ROS/JNK signaling pathway in human gastric cancer cells.
Wang Z; Yu K; Hu Y; Su F; Gao Z; Hu T; Yang Y; Cao X; Qian F
Biochem Pharmacol; 2020 Mar; 173():113673. PubMed ID: 31629709
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