Terms: = Gastric cancer AND PIM1, PIM, 5292, ENSG00000137193, P11309 AND Treatment
11 results:
1. Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and pim-1 kinase enzymes.
El-Miligy MMM; Al-Kubeisi AK; El-Zemity SR; Nassra RA; Abu-Serie MM; Hazzaa AA
Bioorg Chem; 2021 Oct; 115():105171. PubMed ID: 34303896
[TBL] [Abstract] [Full Text] [Related]
2. Pan-pim Kinase Inhibitor AZD1208 Suppresses Tumor Growth and Synergistically Interacts with Akt Inhibition in gastric cancer Cells.
Lee M; Lee KH; Min A; Kim J; Kim S; Jang H; Lim JM; Kim SH; Ha DH; Jeong WJ; Suh KJ; Yang YW; Kim TY; Oh DY; Bang YJ; Im SA
Cancer Res Treat; 2019 Apr; 51(2):451-463. PubMed ID: 29879757
[TBL] [Abstract] [Full Text] [Related]
3. MiR-144 functions as tumor suppressor by targeting pim1 in gastric cancer.
Ren K; Liu QQ; An ZF; Zhang DP; Chen XH
Eur Rev Med Pharmacol Sci; 2017 Jul; 21(13):3028-3037. PubMed ID: 28742204
[TBL] [Abstract] [Full Text] [Related]
4. Activation of pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
An N; Xiong Y; LaRue AC; Kraft AS; Cen B
Cancer Res; 2015 Dec; 75(24):5318-28. PubMed ID: 26670562
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5. Kaempferol enhances the suppressive function of Treg cells by inhibiting FOXP3 phosphorylation.
Lin F; Luo X; Tsun A; Li Z; Li D; Li B
Int Immunopharmacol; 2015 Oct; 28(2):859-65. PubMed ID: 25870037
[TBL] [Abstract] [Full Text] [Related]
6. A small-molecule inhibitor of pim kinases as a potential treatment for urothelial carcinomas.
Foulks JM; Carpenter KJ; Luo B; Xu Y; Senina A; Nix R; Chan A; Clifford A; Wilkes M; Vollmer D; Brenning B; Merx S; Lai S; McCullar MV; Ho KK; Albertson DJ; Call LT; Bearss JJ; Tripp S; Liu T; Stephens BJ; Mollard A; Warner SL; Bearss DJ; Kanner SB
Neoplasia; 2014 May; 16(5):403-12. PubMed ID: 24953177
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7. T-18, a stemonamide synthetic intermediate inhibits pim kinase activity and induces cell apoptosis, acting as a potent anticancer drug.
Wang Z; Li XM; Shang K; Zhang P; Wang CF; Xin YH; Zhou L; Li YY
Oncol Rep; 2013 Mar; 29(3):1245-51. PubMed ID: 23314349
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8. Identification of a phenanthrene derivative as a potent anticancer drug with pim kinase inhibitory activity.
Wang YY; Taniguchi T; Baba T; Li YY; Ishibashi H; Mukaida N
Cancer Sci; 2012 Jan; 103(1):107-15. PubMed ID: 21981263
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9. pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.
Kim J; Roh M; Abdulkadir SA
BMC Cancer; 2010 Jun; 10():248. PubMed ID: 20515470
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10. Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis-inducing ability.
Li YY; Wang YY; Taniguchi T; Kawakami T; Baba T; Ishibashi H; Mukaida N
Int J Cancer; 2010 Jul; 127(2):474-84. PubMed ID: 19921695
[TBL] [Abstract] [Full Text] [Related]
11. Distinct gene expression profiles in gastric epithelial cells induced by different clinical isolates of Helicobacter pylori--implication of bacteria and host interaction in gastric carcinogenesis.
Chang YT; Wu MS; Chang YJ; Chen CC; Lin YS; Hsieh T; Yang PC; Lin JT
Hepatogastroenterology; 2006; 53(70):484-90. PubMed ID: 16995446
[TBL] [Abstract] [Full Text] [Related]
