Terms: = Gastric cancer AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C
117 results:
1. Impact of the Helicobacter pylori Oncoprotein CagA in gastric Carcinogenesis.
Hatakeyama M
Curr Top Microbiol Immunol; 2023; 444():239-257. PubMed ID: 38231221
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2. Expression and prognostic value of APOBEC2 in gastric adenocarcinoma and its association with tumor-infiltrating immune cells.
Wei L; Wu X; Wang L; Chen L; Wu X; Song T; Wang Y; Chang W; Guo A; Niu Y; Huang H
BMC Cancer; 2024 Jan; 24(1):15. PubMed ID: 38166744
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3. M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of shp2 in tumor-associated macrophages.
Zhang S; Ren D; Hou H; Yao L; Yuan H
Aging (Albany NY); 2023 Dec; 15(24):15525-15534. PubMed ID: 38159254
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4. Sperm protein antigen 17 and Sperm flagellar 1 cancer testis antigens are expressed in a rare case of ciliated foregut cyst of the common hepatic duct.
Grizzi F; Chiriva-Internati M; Miranda E; Zaharie R; Hajjar NA; Zaharie F; Del Arco CD; Fernández-Aceñero MJ; Bresalier RS; Moiş E
Pathol Res Pract; 2023 Jul; 247():154546. PubMed ID: 37224658
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5. Exploring the Potential Mechanism of Action of Ursolic Acid against gastric cancer and COVID-19 using Network Pharmacology and Bioinformatics Analysis.
Liu Z; Huang H; Yu Y; Jia Y; Li L; Shi X; Wang F
Curr Pharm Des; 2023; 29(16):1274-1292. PubMed ID: 37218202
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6. The inaccuracies of gastric adenocarcinoma clinical staging and its predictive factors.
Janczewski LM; Shah D; Wells A; Bentrem DJ; Abad JD; Chawla A
J Surg Oncol; 2023 Jun; 127(7):1116-1124. PubMed ID: 36905333
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7. Discovery of allosteric shp2 inhibitors through ensemble-based consensus molecular docking, endpoint and absolute binding free energy calculations.
Jama M; Ahmed M; Jutla A; Wiethan C; Kumar J; Moon TC; West F; Overduin M; Barakat KH
Comput Biol Med; 2023 Jan; 152():106442. PubMed ID: 36566625
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8. shp2 inhibition mitigates adaptive resistance to MEK inhibitors in KRAS-mutant gastric cancer through the suppression of KSR1 activity.
Zheng W; Yang Z; Song P; Sun Y; Liu P; Yue L; Lv K; Wang X; Shen Y; Si J; Zhang X; Ke Y; Cheng H; Hu W
Cancer Lett; 2023 Feb; 555():216029. PubMed ID: 36493900
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9. Trastuzumab combined chemotherapy for the treatment of HER2-positive advanced gastric cancer: A systematic review and meta-analysis of randomized controlled trial.
Xue C; Xu YH
Medicine (Baltimore); 2022 Aug; 101(34):e29992. PubMed ID: 36042610
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10. Helicobacter pylori-induced DNA double-stranded break in the development of gastric cancer.
Murata-Kamiya N; Hatakeyama M
Cancer Sci; 2022 Jun; 113(6):1909-1918. PubMed ID: 35359025
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11. Clinical considerations for the design of PROTACs in cancer.
Nieto-Jiménez C; Morafraile EC; Alonso-Moreno C; Ocaña A
Mol Cancer; 2022 Mar; 21(1):67. PubMed ID: 35249548
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12. KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target.
Wei Y; Ren X; Galbo PM; Moerdler S; Wang H; Sica RA; Etemad-Gilbertson B; Shi L; Zhu L; Tang X; Lin Q; Peng M; Guan F; Zheng D; Chinai JM; Zang X
Sci Immunol; 2021 Jul; 6(61):. PubMed ID: 34244312
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13. Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis.
Imai S; Ooki T; Murata-Kamiya N; Komura D; Tahmina K; Wu W; Takahashi-Kanemitsu A; Knight CT; Kunita A; Suzuki N; Del Valle AA; Tsuboi M; Hata M; Hayakawa Y; Ohnishi N; Ueda K; Fukayama M; Ushiku T; Ishikawa S; Hatakeyama M
Cell Host Microbe; 2021 Jun; 29(6):941-958.e10. PubMed ID: 33989515
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14. Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells.
Fujii Y; Murata-Kamiya N; Hatakeyama M
Cancer Sci; 2020 May; 111(5):1596-1606. PubMed ID: 32198795
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15. Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis.
Takahashi-Kanemitsu A; Knight CT; Hatakeyama M
Cell Mol Immunol; 2020 Jan; 17(1):50-63. PubMed ID: 31804619
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16. Structure based design of selective shp2 inhibitors by De novo design, synthesis and biological evaluation.
Liu WS; Jin WY; Zhou L; Lu XH; Li WY; Ma Y; Wang RL
J Comput Aided Mol Des; 2019 Aug; 33(8):759-774. PubMed ID: 31300938
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17. Malignant Helicobacter pylori-Associated Diseases: gastric cancer and MALT Lymphoma.
Hatakeyama M
Adv Exp Med Biol; 2019; 1149():135-149. PubMed ID: 31016622
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18. Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate.
Hashi K; Imai C; Yahara K; Tahmina K; Hayashi T; Azuma T; Miyabe-Nishiwaki T; Sato H; Matsuoka M; Niimi S; Okamoto M; Hatakeyama M
Sci Rep; 2018 Oct; 8(1):15981. PubMed ID: 30374120
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19. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and shp2 inhibition.
Wong GS; Zhou J; Liu JB; Wu Z; Xu X; Li T; Xu D; Schumacher SE; Puschhof J; McFarland J; Zou C; Dulak A; Henderson L; Xu P; O'Day E; Rendak R; Liao WL; Cecchi F; Hembrough T; Schwartz S; Szeto C; Rustgi AK; Wong KK; Diehl JA; Jensen K; Graziano F; Ruzzo A; Fereshetian S; Mertins P; Carr SA; Beroukhim R; Nakamura K; Oki E; Watanabe M; Baba H; Imamura Y; Catenacci D; Bass AJ
Nat Med; 2018 Jul; 24(7):968-977. PubMed ID: 29808010
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20. Pathogenic Germline Variants in 10,389 Adult cancers.
Huang KL; Mashl RJ; Wu Y; Ritter DI; Wang J; Oh C; Paczkowska M; Reynolds S; Wyczalkowski MA; Oak N; Scott AD; Krassowski M; Cherniack AD; Houlahan KE; Jayasinghe R; Wang LB; Zhou DC; Liu D; Cao S; Kim YW; Koire A; McMichael JF; Hucthagowder V; Kim TB; Hahn A; Wang C; McLellan MD; Al-Mulla F; Johnson KJ; ; Lichtarge O; Boutros PC; Raphael B; Lazar AJ; Zhang W; Wendl MC; Govindan R; Jain S; Wheeler D; Kulkarni S; Dipersio JF; Reimand J; Meric-Bernstam F; Chen K; Shmulevich I; Plon SE; Chen F; Ding L
Cell; 2018 Apr; 173(2):355-370.e14. PubMed ID: 29625052
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