BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Clinical Outcome
53 results:

  • 1. Molecular and clinicopathological implications of PRAME expression in adult glioma.
    Le MK; Vuong HG; Dunn IF; Kondo T
    PLoS One; 2023; 18(10):e0290542. PubMed ID: 37796789
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer.
    Urbaniak A; Reed MR; Heflin B; Gaydos J; Piña-Oviedo S; Jędrzejczyk M; Klejborowska G; Stępczyńska N; Chambers TC; Tackett AJ; Rodriguez A; Huczyński A; Eoff RL; MacNicol AM
    Biomed Pharmacother; 2022 Sep; 153():113440. PubMed ID: 36076555
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. MrgprF acts as a tumor suppressor in cutaneous melanoma by restraining PI3K/akt signaling.
    Shen Q; Han Y; Wu K; He Y; Jiang X; Liu P; Xia C; Xiong Q; Liu R; Chen Q; Zhang Y; Zhao S; Yang C; Chen Y
    Signal Transduct Target Ther; 2022 May; 7(1):147. PubMed ID: 35504869
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. CCL2 activates akt signaling to promote glycolysis and chemoresistance in glioma cells.
    Qian Y; Ding P; Xu J; Nie X; Lu B
    Cell Biol Int; 2022 May; 46(5):819-828. PubMed ID: 35178826
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting PI3K/akt signaling pathway.
    Niu Z; Li Y; Xu Y; Jiang W; Tao R; Chen Y; Han Y
    Bioengineered; 2021 Dec; 12(2):12193-12205. PubMed ID: 34783295
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP cells and Maintains cell Survival.
    Giordano F; Naimo GD; Nigro A; Romeo F; Paolì A; De Amicis F; Vivacqua A; Morelli C; Mauro L; Panno ML
    Drug Des Devel Ther; 2019; 13():4265-4274. PubMed ID: 31908413
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. A Radiosensitivity Gene Signature and PD-L1 Status Predict clinical outcome of Patients with Glioblastoma Multiforme in The Cancer Genome Atlas Dataset.
    Jang BS; Kim IA
    Cancer Res Treat; 2020 Apr; 52(2):530-542. PubMed ID: 31801317
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
    Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
    Cancer Lett; 2020 Jan; 469():195-206. PubMed ID: 31672491
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-akt1 Complex Modulates Glioblastoma Therapy Sensitivity.
    Vehlow A; Klapproth E; Jin S; Hannen R; Hauswald M; Bartsch JW; Nimsky C; Temme A; Leitinger B; Cordes N
    Cell Rep; 2019 Mar; 26(13):3672-3683.e7. PubMed ID: 30917320
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Distinct Molecular Profiles and Immunotherapy Treatment outcomes of V600E and V600K
    Pires da Silva I; Wang KYX; Wilmott JS; Holst J; Carlino MS; Park JJ; Quek C; Wongchenko M; Yan Y; Mann G; Johnson DB; McQuade JL; Rai R; Kefford RF; Rizos H; Scolyer RA; Yang JYH; Long GV; Menzies AM
    Clin Cancer Res; 2019 Feb; 25(4):1272-1279. PubMed ID: 30630828
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Loss of Phd2 cooperates with BRAF
    Liu S; Zhang G; Guo J; Chen X; Lei J; Ze K; Dong L; Dai X; Gao Y; Song D; Ecker BL; Yang R; Feltcher C; Peng K; Feng C; Chen H; Lee RX; Kerestes H; Niu J; Kumar S; Xu W; Zhang J; Wei Z; Martin JS; Liu X; Mills G; Lu Y; Guo W; Sun L; Zhang L; Weeraratna A; Herlyn M; Wei W; Lee FS; Xu X
    Nat Commun; 2018 Dec; 9(1):5426. PubMed ID: 30575721
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The deubiquitinating enzyme UCHL1 is a favorable prognostic marker in neuroblastoma as it promotes neuronal differentiation.
    Gu Y; Lv F; Xue M; Chen K; Cheng C; Ding X; Jin M; Xu G; Zhang Y; Wu Z; Zheng L; Wu Y
    J Exp Clin Cancer Res; 2018 Oct; 37(1):258. PubMed ID: 30359286
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Revisiting the clinical and Biologic Relevance of Partial PTEN Loss in Melanoma.
    Giles KM; Rosenbaum BE; Berger M; Izsak A; Li Y; Illa Bochaca I; Vega-Saenz de Miera E; Wang J; Darvishian F; Zhong H; Osman I
    J Invest Dermatol; 2019 Feb; 139(2):430-438. PubMed ID: 30148988
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Autophagy-induced KDR/VEGFR-2 activation promotes the formation of vasculogenic mimicry by glioma stem cells.
    Wu HB; Yang S; Weng HY; Chen Q; Zhao XL; Fu WJ; Niu Q; Ping YF; Wang JM; Zhang X; Yao XH; Bian XW
    Autophagy; 2017 Sep; 13(9):1528-1542. PubMed ID: 28812437
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Continuous Petri Nets and microRNA Analysis in Melanoma.
    Russo G; Pennisi M; Boscarino R; Pappalardo F
    IEEE/ACM Trans Comput Biol Bioinform; 2018; 15(5):1492-1499. PubMed ID: 28767374
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. TIAM1 variants improve clinical outcome in neuroblastoma.
    Sanmartín E; Yáñez Y; Fornés-Ferrer V; Zugaza JL; Cañete A; Castel V; Font de Mora J
    Oncotarget; 2017 Jul; 8(28):45286-45297. PubMed ID: 28423360
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/akt signaling in glioma.
    Song Y; Zheng S; Wang J; Long H; Fang L; Wang G; Li Z; Que T; Liu Y; Li Y; Zhang X; Fang W; Qi S
    Oncotarget; 2017 Jun; 8(26):41947-41962. PubMed ID: 28410212
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Polymorphisms of insulin receptor substrate 2 are putative biomarkers for pediatric medulloblastoma: considering the genetic susceptibility and pathological diagnoses.
    Baocheng W; Zhao Y; Meng W; Han Y; Wang J; Liu F; Qin S; Ma J
    Nagoya J Med Sci; 2017 Feb; 79(1):47-54. PubMed ID: 28303061
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition.
    Craveiro RB; Ehrhardt M; Velz J; Olschewski M; Goetz B; Pietsch T; Dilloo D
    Oncotarget; 2017 Jul; 8(29):46915-46927. PubMed ID: 28159923
    [TBL] [Abstract] [Full Text] [Related]  


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