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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND ALK, CD246, ENSG00000171094, 238, Q9UM73, TFG/ALK AND Clinical Outcome
22 results:

  • 1. Methylation subgroup and molecular heterogeneity is a hallmark of glioblastoma: implications for biopsy targeting, classification and therapy.
    Gempt J; Withake F; Aftahy AK; Meyer HS; Barz M; Delbridge C; Liesche-Starnecker F; Prokop G; Pfarr N; Schlegel J; Meyer B; Zimmer C; Menze BH; Wiestler B
    ESMO Open; 2022 Oct; 7(5):100566. PubMed ID: 36055049
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Combined Detection of Copy Number Variations of MYCN and alk using Droplet Digital Polymerase Chain Reaction to Identify High-Risk Patients with Neuroblastoma.
    Trivedi T; Panchal K; Bhalala N; Trivedi P; Panchal H
    World Neurosurg; 2022 Mar; 159():e48-e57. PubMed ID: 34861448
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targetable molecular alterations in congenital glioblastoma.
    Gilani A; Donson A; Davies KD; Whiteway SL; Lake J; DeSisto J; Hoffman L; Foreman NK; Kleinschmidt-DeMasters BK; Green AL
    J Neurooncol; 2020 Jan; 146(2):247-252. PubMed ID: 31875306
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A kinome-wide RNAi screen identifies alk as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment.
    Shen J; Najafi S; Stäble S; Fabian J; Koeneke E; Kolbinger FR; Wrobel JK; Meder B; Distel M; Heimburg T; Sippl W; Jung M; Peterziel H; Kranz D; Boutros M; Westermann F; Witt O; Oehme I
    Cell Death Differ; 2018 Dec; 25(12):2053-2070. PubMed ID: 29515255
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The difficulty of predicting clinical outcome after intended submaximal resection of large vestibular Schwannomas.
    MacKenzie R; Sporns P; Zoubi T; Koopmann M; Ewelt C; Stummer W; Brokinkel B; Suero Molina E
    J Clin Neurosci; 2018 Apr; 50():62-68. PubMed ID: 29429787
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. TIAM1 variants improve clinical outcome in neuroblastoma.
    Sanmartín E; Yáñez Y; Fornés-Ferrer V; Zugaza JL; Cañete A; Castel V; Font de Mora J
    Oncotarget; 2017 Jul; 8(28):45286-45297. PubMed ID: 28423360
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Anaplastic lymphoma kinase expression and gene alterations in glioblastoma: correlations with clinical outcome.
    Karagkounis G; Stranjalis G; Argyrakos T; Pantelaion V; Mastoris K; Rontogianni D; Komaitis S; Kalamatianos T; Sakas D; Tiniakos D
    J Clin Pathol; 2017 Jul; 70(7):593-599. PubMed ID: 27993946
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.
    Chen YB; Xu J; Skanderup AJ; Dong Y; Brannon AR; Wang L; Won HH; Wang PI; Nanjangud GJ; Jungbluth AA; Li W; Ojeda V; Hakimi AA; Voss MH; Schultz N; Motzer RJ; Russo P; Cheng EH; Giancotti FG; Lee W; Berger MF; Tickoo SK; Reuter VE; Hsieh JJ
    Nat Commun; 2016 Oct; 7():13131. PubMed ID: 27713405
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.
    Wiesner T; He J; Yelensky R; Esteve-Puig R; Botton T; Yeh I; Lipson D; Otto G; Brennan K; Murali R; Garrido M; Miller VA; Ross JS; Berger MF; Sparatta A; Palmedo G; Cerroni L; Busam KJ; Kutzner H; Cronin MT; Stephens PJ; Bastian BC
    Nat Commun; 2014; 5():3116. PubMed ID: 24445538
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. New strategies in neuroblastoma: Therapeutic targeting of MYCN and alk.
    Barone G; Anderson J; Pearson AD; Petrie K; Chesler L
    Clin Cancer Res; 2013 Nov; 19(21):5814-21. PubMed ID: 23965898
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. alk amplification and protein expression predict inferior prognosis in neuroblastomas.
    Wang M; Zhou C; Sun Q; Cai R; Li Y; Wang D; Gong L
    Exp Mol Pathol; 2013 Oct; 95(2):124-30. PubMed ID: 23797004
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system.
    Raghunathan A; Wani K; Armstrong TS; Vera-Bolanos E; Fouladi M; Gilbertson R; Gajjar A; Goldman S; Lehman NL; Metellus P; Mikkelsen T; Necesito-Reyes MJ; Omuro A; Packer RJ; Partap S; Pollack IF; Prados MD; Robins HI; Soffietti R; Wu J; Miller CR; Gilbert MR; Aldape KD;
    Brain Pathol; 2013 Sep; 23(5):584-94. PubMed ID: 23452038
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Neonatal neuroblastoma.
    Fisher JPH; Tweddle DA
    Semin Fetal Neonatal Med; 2012 Aug; 17(4):207-215. PubMed ID: 22673527
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Anaplastic Lymphoma Kinase (alk) regulates initiation of transcription of MYCN in neuroblastoma cells.
    Schönherr C; Ruuth K; Kamaraj S; Wang CL; Yang HL; Combaret V; Djos A; Martinsson T; Christensen JG; Palmer RH; Hallberg B
    Oncogene; 2012 Dec; 31(50):5193-200. PubMed ID: 22286764
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Identification of novel prognostic markers in relapsing localized resectable neuroblastoma.
    Parodi F; Passoni L; Massimo L; Luksch R; Gambini C; Rossi E; Zuffardi O; Pistoia V; Pezzolo A
    OMICS; 2011 Mar; 15(3):113-21. PubMed ID: 21319993
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Oncogenic mutations of alk in neuroblastoma.
    Ogawa S; Takita J; Sanada M; Hayashi Y
    Cancer Sci; 2011 Feb; 102(2):302-8. PubMed ID: 21205076
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Mutation-independent anaplastic lymphoma kinase overexpression in poor prognosis neuroblastoma patients.
    Passoni L; Longo L; Collini P; Coluccia AM; Bozzi F; Podda M; Gregorio A; Gambini C; Garaventa A; Pistoia V; Del Grosso F; Tonini GP; Cheng M; Gambacorti-Passerini C; Anichini A; Fossati-Bellani F; Di Nicola M; Luksch R
    Cancer Res; 2009 Sep; 69(18):7338-46. PubMed ID: 19723661
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Oncogenic mutations of alk kinase in neuroblastoma.
    Chen Y; Takita J; Choi YL; Kato M; Ohira M; Sanada M; Wang L; Soda M; Kikuchi A; Igarashi T; Nakagawara A; Hayashi Y; Mano H; Ogawa S
    Nature; 2008 Oct; 455(7215):971-4. PubMed ID: 18923524
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays.
    George RE; Attiyeh EF; Li S; Moreau LA; Neuberg D; Li C; Fox EA; Meyerson M; Diller L; Fortina P; Look AT; Maris JM
    PLoS One; 2007 Feb; 2(2):e255. PubMed ID: 17327916
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. [Genome-wide genetic study of medulloblastoma using allelotype analysis].
    Yin XL; Pang CS; Ng HK
    Zhonghua Bing Li Xue Za Zhi; 2004 Oct; 33(5):413-5. PubMed ID: 15498208
    [TBL] [Abstract] [Full Text] [Related]  


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