BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1
16 results:

  • 1. Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models.
    Chattopadhyay M; Chowdhury AR; Feng T; Assenmacher CA; Radaelli E; Guengerich FP; Avadhani NG
    J Biol Chem; 2019 Jun; 294(26):10336-10348. PubMed ID: 31113867
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer.
    Kuo SH; Yang SY; You SL; Lien HC; Lin CH; Lin PH; Huang CS
    Oncotarget; 2017 Mar; 8(13):20925-20938. PubMed ID: 28178648
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Validation of genetic sequence variants as prognostic factors in early-stage head and neck squamous cell cancer survival.
    Azad AK; Bairati I; Samson E; Cheng D; Mirshams M; Qiu X; Savas S; Waldron J; Wang C; Goldstein D; Xu W; Meyer F; Liu G
    Clin Cancer Res; 2012 Jan; 18(1):196-206. PubMed ID: 22076708
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study.
    Flaherty KT; Lathia C; Frye RF; Schuchter L; Redlinger M; Rosen M; O'Dwyer PJ
    Cancer Chemother Pharmacol; 2011 Nov; 68(5):1111-8. PubMed ID: 21350850
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells.
    Mann A; Tyndale RF
    Eur J Neurosci; 2010 Apr; 31(7):1185-93. PubMed ID: 20345925
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Genetics in melanoma.
    Stahl S; Bar-Meir E; Friedman E; Regev E; Orenstein A; Winkler E
    Isr Med Assoc J; 2004 Dec; 6(12):774-7. PubMed ID: 15609895
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Genotyping for polymorphic drug metabolizing enzymes from paraffin-embedded and immunohistochemically stained tumor samples.
    Rae JM; Cordero KE; Scheys JO; Lippman ME; Flockhart DA; Johnson MD
    Pharmacogenetics; 2003 Aug; 13(8):501-7. PubMed ID: 12893988
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Astroglial CYP1B1 up-regulation in inflammatory/oxidative toxic conditions: IL-1beta effect and protection by N-acetylcysteine.
    Malaplate-Armand C; Ferrari L; Masson C; Siest G; Batt AM
    Toxicol Lett; 2003 Mar; 138(3):243-51. PubMed ID: 12565201
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Cytochrome P450 cyp2d6 genotypes: association with hair colour, Breslow thickness and melanocyte stimulating hormone receptor alleles in patients with malignant melanoma.
    Strange RC; Ellison T; Ichii-Jones F; Bath J; Hoban P; Lear JT; Smith AG; Hutchinson PE; Osborne J; Bowers B; Jones PW; Fryer AA
    Pharmacogenetics; 1999 Jun; 9(3):269-76. PubMed ID: 10471058
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. MGMT- and P450 3A-inhibitors do not sensitize glioblastoma cell cultures against nitrosoureas.
    Kirches E; Scherlach C; von Bossanyi P; Schneider T; Szibor R; Kutz E; Warich-Kirches M; Dietzmann K
    Clin Neuropathol; 1999; 18(1):1-8. PubMed ID: 9988132
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. An analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: evidence for modifier effects.
    Webster AR; Richards FM; MacRonald FE; Moore AT; Maher ER
    Am J Hum Genet; 1998 Oct; 63(4):1025-35. PubMed ID: 9758595
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Debrisoquine hydroxylase gene polymorphism in neurofibromatosis type 1.
    Wundrack I; Sasiadek M; Blin N
    Anticancer Res; 1997; 17(6D):4515-7. PubMed ID: 9494560
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. A population-based case-control study of the cyp2d6 and GSTT1 polymorphisms and malignant brain tumors.
    Kelsey KT; Wrensch M; Zuo ZF; Miike R; Wiencke JK
    Pharmacogenetics; 1997 Dec; 7(6):463-8. PubMed ID: 9429231
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Dextromethorphan as an in vivo probe for the simultaneous determination of cyp2d6 and CYP3A activity.
    Ducharme J; Abdullah S; Wainer IW
    J Chromatogr B Biomed Appl; 1996 Mar; 678(1):113-28. PubMed ID: 8861661
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Human cyp2d6 gene polymorphism in Slovene cancer patients and healthy controls.
    Dolzan V; Rudolf Z; Breskvar K
    Carcinogenesis; 1995 Nov; 16(11):2675-8. PubMed ID: 7586185
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Susceptibility to astrocytoma and meningioma: influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (cyp2d6) loci.
    Elexpuru-Camiruaga J; Buxton N; Kandula V; Dias PS; Campbell D; McIntosh J; Broome J; Jones P; Inskip A; Alldersea J
    Cancer Res; 1995 Oct; 55(19):4237-9. PubMed ID: 7671227
    [TBL] [Abstract] [Full Text] [Related]  


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