Terms: = Germ cell tumor AND DDX3X, DDX14, 1654, ENSG00000215301, DBX, DDX3, HLP2
51 results:
1. AEP-cleaved ddx3x induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments.
Zhang W; Cao L; Yang J; Zhang S; Zhao J; Shi Z; Liao K; Wang H; Chen B; Qian Z; Xu H; Wu L; Liu H; Wang H; Ma C; Qiu Y; Ge J; Chen J; Lin Y
J Clin Invest; 2023 Nov; 134(3):. PubMed ID: 37988165
[TBL] [Abstract] [Full Text] [Related]
2. Ceftriaxone exerts antitumor effects in MYCN-driven retinoblastoma and neuroblastoma by targeting ddx3x for translation repression.
Chittavanich P; Saengwimol D; Roytrakul S; Rojanaporn D; Chaitankar V; Srimongkol A; Anurathapan U; Hongeng S; Kaewkhaw R
Mol Oncol; 2024 Apr; 18(4):918-938. PubMed ID: 37975412
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3. ddx3 Upregulates Hydrogen Peroxide-Induced Melanogenesis in Sk-Mel-2 Human Melanoma cells.
Eom S; Lee S; Lee J; Yeom HD; Lee SG; Lee J
Molecules; 2022 Oct; 27(20):. PubMed ID: 36296601
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4. Anaplastic ganglioglioma-A diagnosis comprising several distinct tumour types.
Reinhardt A; Pfister K; Schrimpf D; Stichel D; Sahm F; Reuss DE; Capper D; Wefers AK; Ebrahimi A; Sill M; Felsberg J; Reifenberger G; Becker A; Prinz M; Staszewski O; Hartmann C; Schittenhelm J; Gramatzki D; Weller M; Olar A; Rushing EJ; Bergmann M; Farrell MA; Blümcke I; Coras R; Beckervordersandforth J; Kim SH; Rogerio F; Dimova PS; Niehusmann P; Unterberg A; Platten M; Pfister SM; Wick W; Herold-Mende C; von Deimling A
Neuropathol Appl Neurobiol; 2022 Dec; 48(7):e12847. PubMed ID: 35977725
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5. Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands.
Zhong J; Yang X; Chen J; He K; Gao X; Wu X; Zhang M; Zhou H; Xiao F; An L; Wang X; Shi Y; Zhang N
Nat Commun; 2022 Aug; 13(1):4795. PubMed ID: 35970825
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6. MicroRNA 3928 Suppresses Glioblastoma through Downregulation of Several Oncogenes and Upregulation of p53.
Mulcahy EQX; Zhang Y; Colόn RR; Cain SR; Gibert MK; Dube CJ; Hafner M; Abounader R
Int J Mol Sci; 2022 Apr; 23(7):. PubMed ID: 35409289
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7. Medulloblastoma-associated mutations in the DEAD-box RNA helicase ddx3x/DED1 cause specific defects in translation.
Brown NP; Vergara AM; Whelan AB; Guerra P; Bolger TA
J Biol Chem; 2021; 296():100296. PubMed ID: 33460649
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8. Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).
Gajjar A; Robinson GW; Smith KS; Lin T; Merchant TE; Chintagumpala M; Mahajan A; Su J; Bouffet E; Bartels U; Schechter T; Hassall T; Robertson T; Nicholls W; Gururangan S; Schroeder K; Sullivan M; Wheeler G; Hansford JR; Kellie SJ; McCowage G; Cohn R; Fisher MJ; Krasin MJ; Stewart CF; Broniscer A; Buchhalter I; Tatevossian RG; Orr BA; Neale G; Klimo P; Boop F; Srinivasan A; Pfister SM; Gilbertson RJ; Onar-Thomas A; Ellison DW; Northcott PA
J Clin Oncol; 2021 Mar; 39(7):822-835. PubMed ID: 33405951
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9. Clinical and mutational profiles of adult medulloblastoma groups.
Wong GC; Li KK; Wang WW; Liu AP; Huang QJ; Chan AK; Poon MF; Chung NY; Wong QH; Chen H; Chan DTM; Liu XZ; Mao Y; Zhang ZY; Shi ZF; Ng HK
Acta Neuropathol Commun; 2020 Nov; 8(1):191. PubMed ID: 33172502
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10. An Architect of the Hindbrain: ddx3x Regulates Normal and Malignant Development.
Hwang GH; Segal RA
Dev Cell; 2020 Aug; 54(4):425-426. PubMed ID: 32841591
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11. ddx3x Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.
Patmore DM; Jassim A; Nathan E; Gilbertson RJ; Tahan D; Hoffmann N; Tong Y; Smith KS; Kanneganti TD; Suzuki H; Taylor MD; Northcott P; Gilbertson RJ
Dev Cell; 2020 Aug; 54(4):455-470.e5. PubMed ID: 32553121
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12. Multi-omic analysis reveals significantly mutated genes and ddx3x as a sex-specific tumor suppressor in cutaneous melanoma.
Alkallas R; Lajoie M; Moldoveanu D; Hoang KV; Lefrançois P; Lingrand M; Ahanfeshar-Adams M; Watters K; Spatz A; Zippin JH; Najafabadi HS; Watson IR
Nat Cancer; 2020 Jun; 1(6):635-652. PubMed ID: 35121978
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13. Brain tumour homogenates analysed by surface-enhanced Raman spectroscopy: Discrimination among healthy and cancer cells.
Kowalska AA; Berus S; Szleszkowski Ł; Kamińska A; Kmiecik A; Ratajczak-Wielgomas K; Jurek T; Zadka Ł
Spectrochim Acta A Mol Biomol Spectrosc; 2020 Apr; 231():117769. PubMed ID: 31787534
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14. Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics.
Indira Chandran V; Welinder C; Gonçalves de Oliveira K; Cerezo-Magaña M; Månsson AS; Johansson MC; Marko-Varga G; Belting M
J Neurooncol; 2019 Sep; 144(3):477-488. PubMed ID: 31414377
[TBL] [Abstract] [Full Text] [Related]
15. The X-Linked ddx3x RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma.
Phung B; Cieśla M; Sanna A; Guzzi N; Beneventi G; Cao Thi Ngoc P; Lauss M; Cabrita R; Cordero E; Bosch A; Rosengren F; Häkkinen J; Griewank K; Paschen A; Harbst K; Olsson H; Ingvar C; Carneiro A; Tsao H; Schadendorf D; Pietras K; Bellodi C; Jönsson G
Cell Rep; 2019 Jun; 27(12):3573-3586.e7. PubMed ID: 31216476
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16. Engineering Genetic Predisposition in Human Neuroepithelial Stem cells Recapitulates Medulloblastoma tumorigenesis.
Huang M; Tailor J; Zhen Q; Gillmor AH; Miller ML; Weishaupt H; Chen J; Zheng T; Nash EK; McHenry LK; An Z; Ye F; Takashima Y; Clarke J; Ayetey H; Cavalli FMG; Luu B; Moriarity BS; Ilkhanizadeh S; Chavez L; Yu C; Kurian KM; Magnaldo T; Sevenet N; Koch P; Pollard SM; Dirks P; Snyder MP; Largaespada DA; Cho YJ; Phillips JJ; Swartling FJ; Morrissy AS; Kool M; Pfister SM; Taylor MD; Smith A; Weiss WA
Cell Stem Cell; 2019 Sep; 25(3):433-446.e7. PubMed ID: 31204176
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17. Principles of tumorigenesis and emerging molecular drivers of SHH-activated medulloblastomas.
Menyhárt O; Győrffy B
Ann Clin Transl Neurol; 2019 May; 6(5):990-1005. PubMed ID: 31139698
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18. Costs associated with adverse events for systemic therapies in metastatic melanoma.
Fu AZ; Li Z; Tang J; Mahmood S; Whisman T; Qiu Y
J Comp Eff Res; 2018 Sep; 7(9):867-879. PubMed ID: 30192155
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19. Medulloblastoma, WNT-activated/SHH-activated: clinical impact of molecular analysis and histogenetic evaluation.
Cambruzzi E
Childs Nerv Syst; 2018 May; 34(5):809-815. PubMed ID: 29582169
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20. A CK1 FRET biosensor reveals that ddx3x is an essential activator of CK1ε.
Dolde C; Bischof J; Grüter S; Montada A; Halekotte J; Peifer C; Kalbacher H; Baumann U; Knippschild U; Suter B
J Cell Sci; 2018 Jan; 131(1):. PubMed ID: 29222110
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