BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND DNMT3A, Q9Y6K1, 1788, ENSG00000119772, DNMT3A2, M_HsaIIIA
75 results:

  • 1. dCas9/CRISPR-based methylation of O-6-methylguanine-DNA methyltransferase enhances chemosensitivity to temozolomide in malignant glioma.
    Zapanta Rinonos S; Li T; Pianka ST; Prins TJ; Eldred BSC; Kevan BM; Liau LM; Nghiemphu PL; Cloughesy TF; Lai A
    J Neurooncol; 2024 Jan; 166(1):129-142. PubMed ID: 38224404
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
    Rautajoki KJ; Jaatinen S; Hartewig A; Tiihonen AM; Annala M; Salonen I; Valkonen M; Simola V; Vuorinen EM; Kivinen A; Rauhala MJ; Nurminen R; Maass KK; Lahtela SL; Jukkola A; Yli-Harja O; Helén P; Pajtler KW; Ruusuvuori P; Haapasalo J; Zhang W; Haapasalo H; Nykter M
    Acta Neuropathol Commun; 2023 Nov; 11(1):176. PubMed ID: 37932833
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.
    Bedics G; Szőke P; Bátai B; Nagy T; Papp G; Kránitz N; Rajnai H; Reiniger L; Bödör C; Scheich B
    Sci Rep; 2023 Oct; 13(1):18436. PubMed ID: 37891325
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The evaluation of chitosan hydrogel based curcumin effect on DNMT1, dnmt3a, DNMT3B, MEG3, HOTAIR gene expression in glioblastoma cell line.
    Abolfathi S; Zare M
    Mol Biol Rep; 2023 Jul; 50(7):5977-5989. PubMed ID: 37268862
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Melanoma in a patient with dnmt3a overgrowth syndrome.
    Chen DY; Sutton LA; Ramakrishnan SM; Duncavage EJ; Heath SE; Compton LA; Miller CA; Ley TJ
    Cold Spring Harb Mol Case Stud; 2023 Apr; 9(2):. PubMed ID: 37160317
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. IRX1 is a novel gene, overexpressed in high-grade IDH-mutant astrocytomas.
    Sugur HS; Rao S; Sravya P; Athul Menon K; Arivazhagan A; Mehta B; Santosh V
    Pathol Res Pract; 2023 May; 245():154464. PubMed ID: 37116364
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Loss of p53 Concurrent with RAS and TERT Activation Induces Glioma Formation.
    Gong M; Fan X; Yu H; Niu W; Sun S; Wang H; Chen X
    Mol Neurobiol; 2023 Jun; 60(6):3452-3463. PubMed ID: 36867344
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Assessment of Global DNA Methylation in SH-SY5Y cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam.
    Guler ZR; Yilmaz U; Uzunosmanoglu K; Ozturk B; Abudayyak M; Ozden S
    Int J Toxicol; 2023; 42(4):345-351. PubMed ID: 36723994
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. MGL S3 Chimeric Enzyme Drives Apoptotic Death of EGFR-Dependent Cancer cells through ERK Downregulation.
    Bondarev N; Ivanenko K; Khabusheva E; Lebedev T; Manukhov I; Prassolov V
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361596
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Global and Regional DNA methylation silencing of PPARγ Associated with Glioblastoma Multiforme Pathogenesis.
    Babaeenezhad E; Moradi Sarabi M; Rajabibazl M; Oraee-Yazdani S; Karima S
    Mol Biol Rep; 2023 Jan; 50(1):589-597. PubMed ID: 36355265
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms: A Systematic Review and Meta-analysis.
    Ziogas IA; Tasoudis PT; Borbon LC; Sherman SK; Breheny PJ; Chandrasekharan C; Dillon JS; Bellizzi AM; Howe JR
    Ann Surg Oncol; 2023 Jan; 30(1):148-160. PubMed ID: 36227392
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Inhibiting the growth of melanoma cells via hTERT gene editing using CRISPR-dCas9-dnmt3a system.
    Rad FT; Gargari BN; Ghorbian S; Farsani ZS; Sharifi R
    Gene; 2022 Jun; 828():146477. PubMed ID: 35398175
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Loss of deubiquitylase USP2 triggers development of glioblastoma via TGF-β signaling.
    Tu Y; Xu L; Xu J; Bao Z; Tian W; Ye Y; Sun G; Miao Z; Chao H; You Y; Liu N; Ji J
    Oncogene; 2022 Apr; 41(18):2597-2608. PubMed ID: 35332268
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Comprehensive landscape and interference of clonal haematopoiesis mutations for liquid biopsy: A Chinese pan-cancer cohort.
    Xu E; Su K; Zhou Y; Gong L; Xuan Y; Liao M; Cao J; Li Y; Lu Y; Zhao Y; Chen F
    J Cell Mol Med; 2021 Nov; 25(21):10279-10290. PubMed ID: 34658138
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Molecular alterations in retinoblastoma beyond RB1.
    Mendonça V; Evangelista AC; P Matta B; M Moreira MÂ; Faria P; Lucena E; Seuánez HN
    Exp Eye Res; 2021 Oct; 211():108753. PubMed ID: 34478740
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3A.
    Tanabe R; Miyazono K; Todo T; Saito N; Iwata C; Komuro A; Sakai S; Raja E; Koinuma D; Morikawa M; Westermark B; Heldin CH
    Mol Oncol; 2022 Jan; 16(1):269-288. PubMed ID: 34214250
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. dnmt3a deficiency in the skin causes focal, canonical DNA hypomethylation and a cellular proliferation phenotype.
    Chen DY; Ferguson IM; Braun KA; Sutton LA; Helton NM; Ramakrishnan SM; Smith AM; Miller CA; Ley TJ
    Proc Natl Acad Sci U S A; 2021 Apr; 118(16):. PubMed ID: 33846253
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Chronic Immune-Related Adverse Events Following Adjuvant Anti-PD-1 Therapy for High-risk Resected Melanoma.
    Patrinely JR; Johnson R; Lawless AR; Bhave P; Sawyers A; Dimitrova M; Yeoh HL; Palmeri M; Ye F; Fan R; Davis EJ; Rapisuwon S; Long GV; Haydon A; Osman I; Mehnert JM; Carlino MS; Sullivan RJ; Menzies AM; Johnson DB
    JAMA Oncol; 2021 May; 7(5):744-748. PubMed ID: 33764387
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Expression and prognostic characteristics of m
    Li X; Meng Y
    J Cell Mol Med; 2021 Feb; 25(3):1383-1393. PubMed ID: 33400376
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Acute Myeloid Leukemia Case Harboring Unusual FLT3 Variant: Somatic vs germline?
    Singh N; Morlote D; Vnencak-Jones C; Papadantonakis N; Harada S
    Lab Med; 2021 May; 52(3):e53-e56. PubMed ID: 33283233
    [TBL] [Abstract] [Full Text] [Related]  


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