BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND DROSHA, HSA242976, 29102, RNASEN, ENSG00000113360, Q9NRR4, RNASE3L, RN3, RANSE3L, Etohi2
22 results:

  • 1. Benign and Malignant tumors of the Pineal Region.
    Upadhyayula PS; Neira JA; Miller ML; Bruce JN
    Adv Exp Med Biol; 2023; 1405():153-173. PubMed ID: 37452938
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Histopathology and molecular pathology of pediatric pineal parenchymal tumors.
    Vasiljevic A
    Childs Nerv Syst; 2023 Sep; 39(9):2273-2284. PubMed ID: 35972537
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The DGCR8 E518K mutation found in Wilms tumors leads to a partial miRNA processing defect that alters gene expression patterns and biological processes.
    Vardapour R; Kehl T; Kneitz S; Ludwig N; Meese E; Lenhof HP; Gessler M
    Carcinogenesis; 2022 Mar; 43(2):82-93. PubMed ID: 34919667
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Factors Involved in miRNA Processing Change Its Expression Level during Imitation of Hypoxia in BeWo b30 cells.
    Nersisyan SA; Shkurnikov MY; Knyazev EN
    Dokl Biochem Biophys; 2020 Jul; 493(1):205-207. PubMed ID: 32894466
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Pineal Gland tumor Microenvironment.
    Choque-Velasquez J; Baluszek S; Colasanti R; Muhammad S; Hernesniemi J
    Adv Exp Med Biol; 2020; 1296():137-150. PubMed ID: 34185290
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain tumor Consortium registry study.
    Li BK; Vasiljevic A; Dufour C; Yao F; Ho BLB; Lu M; Hwang EI; Gururangan S; Hansford JR; Fouladi M; Nobusawa S; Laquerriere A; Delisle MB; Fangusaro J; Forest F; Toledano H; Solano-Paez P; Leary S; Birks D; Hoffman LM; Szathmari A; Faure-Conter C; Fan X; Catchpoole D; Zhou L; Schultz KAP; Ichimura K; Gauchotte G; Jabado N; Jones C; Loussouarn D; Mokhtari K; Rousseau A; Ziegler DS; Tanaka S; Pomeroy SL; Gajjar A; Ramaswamy V; Hawkins C; Grundy RG; Hill DA; Bouffet E; Huang A; Jouvet A
    Acta Neuropathol; 2020 Feb; 139(2):223-241. PubMed ID: 31820118
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.
    Liu APY; Gudenas B; Lin T; Orr BA; Klimo P; Kumar R; Bouffet E; Gururangan S; Crawford JR; Kellie SJ; Chintagumpala M; Fisher MJ; Bowers DC; Hassall T; Indelicato DJ; Onar-Thomas A; Ellison DW; Boop FA; Merchant TE; Robinson GW; Northcott PA; Gajjar A
    Acta Neuropathol; 2020 Feb; 139(2):259-271. PubMed ID: 31802236
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.
    Pfaff E; Aichmüller C; Sill M; Stichel D; Snuderl M; Karajannis MA; Schuhmann MU; Schittenhelm J; Hasselblatt M; Thomas C; Korshunov A; Rhizova M; Wittmann A; Kaufhold A; Iskar M; Ketteler P; Lohmann D; Orr BA; Ellison DW; von Hoff K; Mynarek M; Rutkowski S; Sahm F; von Deimling A; Lichter P; Kool M; Zapatka M; Pfister SM; Jones DTW
    Acta Neuropathol; 2020 Feb; 139(2):243-257. PubMed ID: 31768671
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Structural Differences between Pri-miRNA Paralogs Promote Alternative drosha Cleavage and Expand Target Repertoires.
    Bofill-De Ros X; Kasprzak WK; Bhandari Y; Fan L; Cavanaugh Q; Jiang M; Dai L; Yang A; Shao TJ; Shapiro BA; Wang YX; Gu S
    Cell Rep; 2019 Jan; 26(2):447-459.e4. PubMed ID: 30625327
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Recurrent homozygous deletion of drosha and microduplication of PDE4DIP in pineoblastoma.
    Snuderl M; Kannan K; Pfaff E; Wang S; Stafford JM; Serrano J; Heguy A; Ray K; Faustin A; Aminova O; Dolgalev I; Stapleton SL; Zagzag D; Chiriboga L; Gardner SL; Wisoff JH; Golfinos JG; Capper D; Hovestadt V; Rosenblum MK; Placantonakis DG; LeBoeuf SE; Papagiannakopoulos TY; Chavez L; Ahsan S; Eberhart CG; Pfister SM; Jones DTW; Karajannis MA
    Nat Commun; 2018 Jul; 9(1):2868. PubMed ID: 30030436
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.
    Antoniali G; Serra F; Lirussi L; Tanaka M; D'Ambrosio C; Zhang S; Radovic S; Dalla E; Ciani Y; Scaloni A; Li M; Piazza S; Tell G
    Nat Commun; 2017 Oct; 8(1):797. PubMed ID: 28986522
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. ATRX driver mutation in a composite malignant pheochromocytoma.
    Comino-Méndez I; Tejera ÁM; Currás-Freixes M; Remacha L; Gonzalvo P; Tonda R; Letón R; Blasco MA; Robledo M; Cascón A
    Cancer Genet; 2016 Jun; 209(6):272-7. PubMed ID: 27209355
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. MiR-215 Is Induced Post-transcriptionally via HIF-drosha Complex and Mediates Glioma-Initiating cell Adaptation to Hypoxia by Targeting KDM1B.
    Hu J; Sun T; Wang H; Chen Z; Wang S; Yuan L; Liu T; Li HR; Wang P; Feng Y; Wang Q; McLendon RE; Friedman AH; Keir ST; Bigner DD; Rathmell J; Fu XD; Li QJ; Wang H; Wang XF
    Cancer Cell; 2016 Jan; 29(1):49-60. PubMed ID: 26766590
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. DEAD-box RNA helicase DDX23 modulates glioma malignancy via elevating miR-21 biogenesis.
    Yin J; Park G; Lee JE; Choi EY; Park JY; Kim TH; Park N; Jin X; Jung JE; Shin D; Hong JH; Kim H; Yoo H; Lee SH; Kim YJ; Park JB; Kim JH
    Brain; 2015 Sep; 138(Pt 9):2553-70. PubMed ID: 26121981
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Overexpression of genes involved in miRNA biogenesis in medullary thyroid carcinomas with RET mutation.
    Puppin C; Durante C; Sponziello M; Verrienti A; Pecce V; Lavarone E; Baldan F; Campese AF; Boichard A; Lacroix L; Russo D; Filetti S; Damante G
    Endocrine; 2014 Nov; 47(2):528-36. PubMed ID: 24569963
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. TDP-43 regulates the microprocessor complex activity during in vitro neuronal differentiation.
    Di Carlo V; Grossi E; Laneve P; Morlando M; Dini Modigliani S; Ballarino M; Bozzoni I; Caffarelli E
    Mol Neurobiol; 2013 Dec; 48(3):952-63. PubMed ID: 24113842
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Common genetic variants in the microRNA biogenesis pathway are associated with malignant peripheral nerve sheath tumor risk in a Chinese population.
    Weng Y; Chen Y; Chen J; Liu Y; Bao T
    Cancer Epidemiol; 2013 Dec; 37(6):913-6. PubMed ID: 23763827
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth.
    Nemlich Y; Greenberg E; Ortenberg R; Besser MJ; Barshack I; Jacob-Hirsch J; Jacoby E; Eyal E; Rivkin L; Prieto VG; Chakravarti N; Duncan LM; Kallenberg DM; Galun E; Bennett DC; Amariglio N; Bar-Eli M; Schachter J; Rechavi G; Markel G
    J Clin Invest; 2013 Jun; 123(6):2703-18. PubMed ID: 23728176
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Expression of the RNase III enzyme drosha is reduced during progression of human cutaneous melanoma.
    Jafarnejad SM; Sjoestroem C; Martinka M; Li G
    Mod Pathol; 2013 Jul; 26(7):902-10. PubMed ID: 23370771
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi.
    Sand M; Skrygan M; Georgas D; Sand D; Gambichler T; Altmeyer P; Bechara FG
    Cell Tissue Res; 2012 Oct; 350(1):119-26. PubMed ID: 22706980
    [TBL] [Abstract] [Full Text] [Related]  


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