Terms: = Germ cell tumor AND GNA11, GNA-11, 2767, ENSG00000088256
236 results:
1. Identification and validation of a costimulatory molecule-related signature to predict the prognosis for uveal melanoma patients.
Zhao M; Yu Y; Song Z
Sci Rep; 2024 Apr; 14(1):9146. PubMed ID: 38644411
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2. The Pediatric and Young Adult Choroidal and Ciliary Body Melanoma Genetic Study, A Survey by the European Ophthalmic Oncology Group.
van Poppelen NM; Cassoux N; Turunen JA; Naus NC; Verdijk RM; Vaarwater J; Cohen V; Papastefanou VP; Kiratli H; Saakyan SV; Tsygankov AY; Rospond-Kubiak I; Mudhar HS; Salvi SM; Kiilgaard JF; Heegaard S; Moulin AP; Saornil MA; Garciá-Alvarez C; Fili M; Eide NA; Meyer P; Kivelä TT; de Klein A; Kilic E; Al-Jamal RT
Invest Ophthalmol Vis Sci; 2024 Apr; 65(4):12. PubMed ID: 38573618
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3. Molecular Frontiers in Melanoma: Pathogenesis, Diagnosis, and Therapeutic Advances.
Kim HJ; Kim YH
Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474231
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4. Emerging therapeutic strategies for metastatic uveal melanoma: Targeting driver mutations.
Liu XL; Run-Hua Z; Pan JX; Li ZJ; Yu L; Li YL
Pigment Cell Melanoma Res; 2024 May; 37(3):411-425. PubMed ID: 38411373
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5. Mass Spectrometry-Based Profiling of Histone Post-Translational Modifications in Uveal Melanoma Tissues, Human Melanocytes, and Uveal Melanoma cell Lines - A Pilot Study.
Herwig-Carl MC; Sharma A; Tischler V; Pelusi N; Loeffler KU; Holz FG; Zeschnigk M; Landreville S; Auw-Haedrich C; Noberini R; Bonaldi T
Invest Ophthalmol Vis Sci; 2024 Feb; 65(2):27. PubMed ID: 38349785
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6. Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma.
Lim-Fat MJ; Iorgulescu JB; Rahman R; Bhave V; Muzikansky A; Woodward E; Whorral S; Allen M; Touat M; Li X; Xy G; Patel J; Gerstner ER; Kalpathy-Cramer J; Youssef G; Chukwueke U; McFaline-Figueroa JR; Nayak L; Lee EQ; Reardon DA; Beroukhim R; Huang RY; Bi WL; Ligon KL; Wen PY
Clin Cancer Res; 2024 Apr; 30(7):1327-1337. PubMed ID: 38252427
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7. Cooperative function of oncogenic MAPK signaling and the loss of Pten for melanoma migration through the formation of lamellipodia.
Yasuta Y; Kaminaka R; Nagai S; Mouri S; Ishida K; Tanaka A; Zhou Y; Sakurai H; Yokoyama S
Sci Rep; 2024 Jan; 14(1):1525. PubMed ID: 38233537
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8. INPP5A phosphatase is a synthetic lethal target in GNAQ and gna11-mutant melanomas.
Elbatsh AMO; Amin-Mansour A; Haberkorn A; Textor C; Ebel N; Renard E; Koch LM; Groenveld FC; Piquet M; Naumann U; Ruddy DA; Romanet V; Martínez Gómez JM; Shirley MD; Wipfli P; Schnell C; Wartmann M; Rausch M; Jager MJ; Levesque MP; Maira SM; Manchado E
Nat Cancer; 2024 Mar; 5(3):481-499. PubMed ID: 38233483
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9. Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma.
Visser M; Papillon JPN; Luzzio M; LaMarche MJ; Fan J; Michael W; Wang D; Zhang A; Straub C; Mathieu S; Kato M; Palermo M; Chen C; Ramsey T; Joud C; Barrett R; Vattay A; Guo R; Bric A; Chung F; Liang G; Romanowski MJ; Lam J; Thohan S; Atassi F; Wylie A; Cooke VG
J Med Chem; 2024 Jan; 67(2):1447-1459. PubMed ID: 38198520
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10. Design, synthesis and evaluation of quinazoline derivatives as Gαq/11 proteins inhibitors against uveal melanoma.
Fan G; Liu L; Ye J; Xiao W; Xiong XF
Bioorg Chem; 2024 Feb; 143():107005. PubMed ID: 38043397
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11. Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma.
Baqai U; Kurimchak AM; Trachtenberg IV; Purwin TJ; Haj JI; Han A; Luo K; Pachon NF; Jeon A; Chua V; Davies MA; Gutkind JS; Benovic JL; Duncan JS; Aplin AE
J Biol Chem; 2023 Dec; 299(12):105418. PubMed ID: 37923138
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12. Combined Mcl-1 and YAP1/TAZ inhibition for treatment of metastatic uveal melanoma.
Glinkina KA; Teunisse AFAS; Gelmi MC; de Vries J; Jager MJ; Jochemsen AG
Melanoma Res; 2023 Oct; 33(5):345-356. PubMed ID: 37467061
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13. Trametinib in Patients With
Wisinski KB; Flamand Y; Wilson MA; Luke JJ; Tawbi HA; Hong F; Mitchell EP; Zwiebel JA; Chen H; Gray RJ; Li S; McShane LM; Rubinstein LV; Patton D; Williams PM; Hamilton SR; Behrens RJ; Pennington KP; Conley BA; Arteaga CL; Harris LN; O'Dwyer PJ; Chen AP; Flaherty KT
JCO Precis Oncol; 2023 Apr; 7():e2200421. PubMed ID: 37053535
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14. Real-life use of trametinib after immunotherapy failure in BRAF wild-type advanced melanoma.
Pigné T; Lévy M; Ducharme O; Dutriaux C; Gerard E; Pham-Ledard A; Beylot-Barry M; Prey S
Melanoma Res; 2023 Jun; 33(3):252-256. PubMed ID: 36919691
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15. Molecular profiling of primary uveal melanoma: results of a Polish cohort.
Kowalik A; Karpinski P; Markiewicz A; Orlowska-Heitzman J; Romanowska-Dixon B; Donizy P; Hoang MP
Melanoma Res; 2023 Apr; 33(2):104-115. PubMed ID: 36719926
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16. Genomics and Epigenomics in the Molecular Biology of Melanoma-A Prerequisite for Biomarkers Studies.
Zob DL; Augustin I; Caba L; Panzaru MC; Popa S; Popa AD; Florea L; Gorduza EV
Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36614156
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17. Pamiparib in patients with locally advanced or metastatic HER2-negative breast cancer with germline BRCA mutations: a phase II study.
Xu B; Sun T; Shi Y; Cui J; Yin Y; Ouyang Q; Liu Q; Zhang Q; Chen Y; Wang S; Wang X; Tong Z; Zhong Y; Wang J; Yan M; Yan X; Wang C; Feng J; Wang X; Hu G; Cheng Y; Ge R; Zhu Z; Zhang W; Shao Z
Breast Cancer Res Treat; 2023 Feb; 197(3):489-501. PubMed ID: 36459284
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18. Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal melanoma.
Zhang Y; Zhang B; Li Y; Dai Y; Li J; Li D; Xia Z; Zhang J; Liu P; Chen M; Jiao B; Ren R
Front Med; 2022 Oct; 16(5):784-798. PubMed ID: 35997986
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19. Melanoma arising in extracutaneous cellular blue naevus: report of two cases with comparison to cutaneous counterparts and uveal melanoma.
Jo VY; Russell-Goldman E; Yoon CH; Doyle LA; Hanna J
Histopathology; 2022 Nov; 81(5):625-634. PubMed ID: 35941700
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20. Iris and Ciliary Body Melanocytomas Are Defined by Solitary GNAQ Mutation Without Additional Oncogenic Alterations.
Solomon DA; Ramani B; Eiger-Moscovich M; Milman T; Uludag G; Crawford JB; Phan I; Char DH; Shields CL; Eagle RC; Bastian BC; Bloomer MM; Pekmezci M
Ophthalmology; 2022 Dec; 129(12):1429-1439. PubMed ID: 35835335
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