BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884 AND Treatment
126 results:

  • 1. Network pharmacology-based strategy to investigate the effect and mechanism of α-solanine against glioma.
    Wang C; Liu X; Guo S
    BMC Complement Med Ther; 2023 Oct; 23(1):371. PubMed ID: 37865727
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
    Hou C; Shi S; Gao M; Ji J; Ma C; Wang T; Chen T; Liu Y; Zhong J; Zheng Y; Ye J; Ke Y
    J Neurooncol; 2023 Oct; 165(1):79-90. PubMed ID: 37819535
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Combined BRAF, MEK, and heat-shock protein 90 inhibition in advanced BRAF V600-mutant melanoma.
    Eroglu Z; Chen YA; Smalley I; Li J; Markowitz JK; Brohl AS; Tetteh L; Taylor H; Sondak VK; Khushalani NI; Smalley KSM
    Cancer; 2024 Jan; 130(2):232-243. PubMed ID: 37776537
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Promising targetable biomarkers in pancreatic neuroendocrine tumours.
    Borghesani M; Gervaso L; Cella CA; Benini L; Ciardiello D; Algeri L; Ferrero A; Valenza C; Guidi L; Zampino MG; Spada F; Fazio N
    Expert Rev Endocrinol Metab; 2023; 18(5):387-398. PubMed ID: 37743651
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Molecular mechanism of lycorine in the treatment of glioblastoma based on network pharmacology and molecular docking.
    Su J; Huo M; Xu F; Ding L
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Mar; 397(3):1551-1559. PubMed ID: 37668687
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Identification of circRNA-miRNA-mRNA Network Regulated by hsp90 in Human Melanoma A375 cells.
    Fu Q; Gao H; Liu K; Su J; Zhang J; Guo X; Yang F
    Comb Chem High Throughput Screen; 2024; 27(2):307-316. PubMed ID: 37303182
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. In Vitro Testing of the Virus-Like Drug Conjugate Belzupacap Sarotalocan (AU-011) on Uveal Melanoma Suggests BAP1-Related Immunostimulatory Capacity.
    Ma S; Huis In't Veld RV; Houy A; Stern MH; Rich C; Ossendorp FA; Jager MJ
    Invest Ophthalmol Vis Sci; 2023 Jun; 64(7):10. PubMed ID: 37272766
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.
    Mainwaring OJ; Weishaupt H; Zhao M; Rosén G; Borgenvik A; Breinschmid L; Verbaan AD; Richardson S; Thompson D; Clifford SC; Hill RM; Annusver K; Sundström A; Holmberg KO; Kasper M; Hutter S; Swartling FJ
    Nat Commun; 2023 Mar; 14(1):1221. PubMed ID: 36869047
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Primary tumor resection improves survival of gastrointestinal neuroendocrine carcinoma patients with nonresected liver metastases.
    Chen Q; Li K; Rhodin KE; Masoud SJ; Lidsky ME; Cai J; Wei Q; Luo S; Zhao H
    J Surg Oncol; 2023 May; 127(6):945-955. PubMed ID: 36807890
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Hsp27, Hsp60, Hsp70, or hsp90 depletion enhances the antitumor effects of resveratrol via oxidative and ER stress response in human glioblastoma cells.
    Önay Uçar E; Şengelen A; Mertoğlu Kamalı E
    Biochem Pharmacol; 2023 Feb; 208():115409. PubMed ID: 36603687
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Risk of secondary tumours in patients with non-metastatic and metastatic human retinoblastoma.
    Sadeghi R; Pirankuraim H; Javanshir ST; Arabi M; Bereimipour A; Javanshir HT; Mahmoodzadeh H; Nayernia K
    Eye (Lond); 2023 Aug; 37(11):2327-2334. PubMed ID: 36528757
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Effects of cancer-associated point mutations on the structure, function, and stability of isocitrate dehydrogenase 2.
    Chen X; Yang P; Qiao Y; Ye F; Wang Z; Xu M; Han X; Song L; Wu Y; Ou WB
    Sci Rep; 2022 Nov; 12(1):18830. PubMed ID: 36335201
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells.
    Kıyga E; Adıgüzel Z; Önay Uçar E
    Mol Biol Rep; 2022 Sep; 49(9):8701-8713. PubMed ID: 35752701
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. SK119, a Novel Shikonin Derivative, Leads to Apoptosis in Melanoma cell Lines and Exhibits Synergistic Effects with Vemurafenib and Cobimetinib.
    Kretschmer N; Durchschein C; Hufner A; Rinner B; Lohberger B; Bauer R
    Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628494
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. hsp90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma.
    Sasame J; Ikegaya N; Kawazu M; Natsumeda M; Hayashi T; Isoda M; Satomi K; Tomiyama A; Oshima A; Honma H; Miyake Y; Takabayashi K; Nakamura T; Ueno T; Matsushita Y; Iwashita H; Kanemaru Y; Murata H; Ryo A; Terashima K; Yamanaka S; Fujii Y; Mano H; Komori T; Ichimura K; Cahill DP; Wakimoto H; Yamamoto T; Tateishi K
    Clin Cancer Res; 2022 Jun; 28(11):2425-2439. PubMed ID: 35344043
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. hsp90-CDC37 functions as a chaperone for the oncogenic FGFR3-TACC3 fusion.
    Li T; Mehraein-Ghomi F; Forbes ME; Namjoshi SV; Ballard EA; Song Q; Chou PC; Wang X; Parker Kerrigan BC; Lang FF; Lesser G; Debinski W; Yang X; Zhang W
    Mol Ther; 2022 Apr; 30(4):1610-1627. PubMed ID: 35151844
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
    Xu J; Wu PJ; Lai TH; Sharma P; Canella A; Welker AM; Beattie CE; Elder JB; Easley M; Lonser R; Jacob NK; Pietrzak M; Timmers CM; Lang F; Sampath D; Puduvalli VK
    Clin Cancer Res; 2022 May; 28(9):1979-1990. PubMed ID: 35140124
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. hsp90/IKK-rich small extracellular vesicles activate pro-angiogenic melanoma-associated fibroblasts via the NF-κB/CXCL1 axis.
    Tang H; Zhou X; Zhao X; Luo X; Luo T; Chen Y; Liang W; Jiang E; Liu K; Shao Z; Shang Z
    Cancer Sci; 2022 Apr; 113(4):1168-1181. PubMed ID: 35043517
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Quercetin increases mitochondrial proteins (VDAC and SDH) and downmodulates AXL and PIM-1 tyrosine kinase receptors in NRAS melanoma cells.
    Rocha-Brito KJP; Clerici SP; Cordeiro HG; Scotá Ferreira AP; Barreto Fonseca EM; Gonçalves PR; Abrantes JLF; Milani R; Massaro RR; Maria-Engler SS; Ferreira-Halder CV
    Biol Chem; 2022 Feb; 403(3):293-303. PubMed ID: 34854272
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. A heat shock protein 90 inhibitor reduces oncoprotein expression and induces cell death in heterogeneous glioblastoma cells with EGFR, PDGFRA, CDK4, and NF1 aberrations.
    Ho KT; Chen PF; Chuang JY; Gean PW; Hsueh YS
    Life Sci; 2022 Jan; 288():120176. PubMed ID: 34848192
    [TBL] [Abstract] [Full Text] [Related]  


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