BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132 AND Treatment
27 results:

  • 1. Neuroprotection of Truncated Peptide IIAVE from
    Liu Q; Lin L; Li H; Qian ZJ
    Molecules; 2024 Feb; 29(3):. PubMed ID: 38338436
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Nrf2 protein in melanoma progression, as a new means of treatment.
    Feng Q; Xu X; Zhang S
    Pigment Cell Melanoma Res; 2024 Mar; 37(2):247-258. PubMed ID: 37777339
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Protective Effects and Mechanisms of Pectolinarin against H
    Pang QQ; Kim JH; Kim HY; Kim JH; Cho EJ
    Molecules; 2023 Aug; 28(15):. PubMed ID: 37570795
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. SMURF1 attenuates endoplasmic reticulum stress by promoting the degradation of keap1 to activate NRF2 antioxidant pathway.
    Dong L; Xu M; Li Y; Xu W; Wu C; Zheng H; Xiao Z; Sun G; Ding L; Li X; Li W; Zhou L; Xia Q
    Cell Death Dis; 2023 Jun; 14(6):361. PubMed ID: 37316499
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1.
    Wei J; Wang L; Zhang Y; Sun T; Zhang C; Hu Z; Zhou L; Liu X; Wan J; Ma L
    Oncogene; 2023 Jun; 42(26):2103-2112. PubMed ID: 37188737
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Neuroprotective effect of a keap1-Nrf2 Protein-Protein Inter-action inhibitor on cerebral Ischemia/Reperfusion injury.
    Qi Z; Tong Y; Luo H; Chen M; Zhou N; Chen L
    Bioorg Chem; 2023 Mar; 132():106350. PubMed ID: 36681044
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Exosomal hsa-piR1089 promotes proliferation and migration in neuroblastoma via targeting keap1.
    Wang H; Shi B; Zhang X; Shen P; He Q; Yin M; Pan Y; Ma J
    Pathol Res Pract; 2023 Jan; 241():154240. PubMed ID: 36436316
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Immune Checkpoint Blockade Outcome in Small-cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function.
    Dowlati A; Abbas A; Chan T; Henick B; Wang X; Doshi P; Fu P; Patel J; Kuo F; Chang H; Balli D
    JCO Precis Oncol; 2022 Aug; 6():e2200257. PubMed ID: 36044718
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Activation of Atg7-dependent autophagy by a novel inhibitor of the keap1-Nrf2 protein-protein interaction from
    Sun Y; He L; Wang W; Xie Z; Zhang X; Wang P; Wang L; Yan C; Liu Z; Zhao J; Cui Z; Wang Y; Tang L; Zhang Z
    Food Funct; 2022 Jul; 13(14):7885-7900. PubMed ID: 35776077
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Apatinib Induces Ferroptosis of Glioma cells through Modulation of the VEGFR2/Nrf2 Pathway.
    Xia L; Gong M; Zou Y; Wang Z; Wu B; Zhang S; Li L; Jin K; Sun C
    Oxid Med Cell Longev; 2022; 2022():9925919. PubMed ID: 35602105
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The Role of NRF2/keap1 Pathway in Glioblastoma: Pharmacological Implications.
    Shahcheraghi SH; Salemi F; Alam W; Ashworth H; Saso L; Khan H; Lotfi M
    Med Oncol; 2022 May; 39(5):91. PubMed ID: 35568790
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. TTF-1 and c-MYC-defined Phenotypes of Large cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for treatment Selection.
    Miyagawa-Hayashino A; Okada S; Takeda-Miyata N; Takashima Y; Yamada T; Takemura Y; Uchino J; Inoue M; Takayama K; Konishi E
    Appl Immunohistochem Mol Morphol; 2021 Apr; 29(4):313-320. PubMed ID: 33031101
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Inhibition of Nrf2 might enhance the anti-tumor effect of temozolomide in glioma cells via inhibition of Ras/Raf/MEK signaling pathway.
    Sun W; Zhang W; Yu J; Lu Z; Yu J
    Int J Neurosci; 2021 Oct; 131(10):975-983. PubMed ID: 32378973
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma.
    Pölönen P; Jawahar Deen A; Leinonen HM; Jyrkkänen HK; Kuosmanen S; Mononen M; Jain A; Tuomainen T; Pasonen-Seppänen S; Hartikainen JM; Mannermaa A; Nykter M; Tavi P; Johansen T; Heinäniemi M; Levonen AL
    Oncogene; 2019 Dec; 38(50):7473-7490. PubMed ID: 31444413
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Effects of keap1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung tumors.
    Sparaneo A; Fabrizio FP; la Torre A; Graziano P; Di Maio M; Fontana A; Bisceglia M; Rossi A; Pizzolitto S; De Maglio G; Tancredi A; Grimaldi F; Balsamo T; Centra F; Manzorra MC; Trombetta D; Pantalone A; Bonfitto A; Maiello E; Fazio VM; Muscarella LA
    Int J Mol Sci; 2019 May; 20(10):. PubMed ID: 31126053
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.
    George J; Walter V; Peifer M; Alexandrov LB; Seidel D; Leenders F; Maas L; Müller C; Dahmen I; Delhomme TM; Ardin M; Leblay N; Byrnes G; Sun R; De Reynies A; McLeer-Florin A; Bosco G; Malchers F; Menon R; Altmüller J; Becker C; Nürnberg P; Achter V; Lang U; Schneider PM; Bogus M; Soloway MG; Wilkerson MD; Cun Y; McKay JD; Moro-Sibilot D; Brambilla CG; Lantuejoul S; Lemaitre N; Soltermann A; Weder W; Tischler V; Brustugun OT; Lund-Iversen M; Helland Å; Solberg S; Ansén S; Wright G; Solomon B; Roz L; Pastorino U; Petersen I; Clement JH; Sänger J; Wolf J; Vingron M; Zander T; Perner S; Travis WD; Haas SA; Olivier M; Foll M; Büttner R; Hayes DN; Brambilla E; Fernandez-Cuesta L; Thomas RK
    Nat Commun; 2018 Mar; 9(1):1048. PubMed ID: 29535388
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Cigarette smoke extract and isoprene resulted in the induction of apoptosis and autophagy in human placenta choriocarcinoma JEG-3 cells.
    Lee HM; Choi KC
    Environ Toxicol; 2018 Feb; 33(2):178-190. PubMed ID: 29135079
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy treatment Outcome.
    Derks JL; Leblay N; Thunnissen E; van Suylen RJ; den Bakker M; Groen HJM; Smit EF; Damhuis R; van den Broek EC; Charbrier A; Foll M; McKay JD; Fernandez-Cuesta L; Speel EM; Dingemans AC;
    Clin Cancer Res; 2018 Jan; 24(1):33-42. PubMed ID: 29066508
    [No Abstract]    [Full Text] [Related]  

  • 19. Activation of Nrf2 attenuates carbonyl stress induced by methylglyoxal in human neuroblastoma cells: Increase in GSH levels is a critical event for the detoxification mechanism.
    Nishimoto S; Koike S; Inoue N; Suzuki T; Ogasawara Y
    Biochem Biophys Res Commun; 2017 Feb; 483(2):874-879. PubMed ID: 28073699
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Global SUMOylation facilitates the multimodal neuroprotection afforded by quercetin against the deleterious effects of oxygen/glucose deprivation and the restoration of oxygen/glucose.
    Lee YJ; Bernstock JD; Nagaraja N; Ko B; Hallenbeck JM
    J Neurochem; 2016 Jul; 138(1):101-16. PubMed ID: 27087120
    [TBL] [Abstract] [Full Text] [Related]  


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