BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND KIAA1549, ENSG00000122778, 57670 AND Treatment
49 results:

  • 1. LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.
    van Tilburg CM; Kilburn LB; Perreault S; Schmidt R; Azizi AA; Cruz-Martínez O; Zápotocký M; Scheinemann K; Meeteren AYNS; Sehested A; Opocher E; Driever PH; Avula S; Ziegler DS; Capper D; Koch A; Sahm F; Qiu J; Tsao LP; Blackman SC; Manley P; Milde T; Witt R; Jones DTW; Hargrave D; Witt O
    BMC Cancer; 2024 Jan; 24(1):147. PubMed ID: 38291372
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. treatment evaluation by volumetric segmentation in pediatric optic pathway glioma: evaluation of the effect of bevacizumab on intra-tumor components.
    Bennebroek CA; Schouten CR; Montauban-van Swijndregt MC; Saeed P; Porro GL; Pott JWR; Dittrich ATM; Oostenbrink R; Schouten-van Meeteren AY; de Jong MC; de Graaf P
    J Neurooncol; 2024 Jan; 166(1):79-87. PubMed ID: 38150061
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Unraveling the signaling mechanism behind astrocytoma and possible therapeutics strategies: A comprehensive review.
    Nahar Metu CL; Sutihar SK; Sohel M; Zohora F; Hasan A; Miah MT; Rani Kar T; Hossain MA; Rahman MH
    Cancer Rep (Hoboken); 2023 Oct; 6(10):e1889. PubMed ID: 37675821
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Pathophysiological evaluation of pilocytic astrocytoma in adults: Histopathological and immunohistochemical analysis.
    Santino SF; Salles D; Stávale JN; Malinverni ACM
    Pathol Res Pract; 2023 Aug; 248():154593. PubMed ID: 37331182
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.
    Hardin EC; Schmid S; Sommerkamp A; Bodden C; Heipertz AE; Sievers P; Wittmann A; Milde T; Pfister SM; von Deimling A; Horn S; Herz NA; Simon M; Perera AA; Azizi A; Cruz O; Curry S; Van Damme A; Garami M; Hargrave D; Kattamis A; Kotnik BF; Lähteenmäki P; Scheinemann K; Schouten-van Meeteren AYN; Sehested A; Viscardi E; Wormdal OM; Zapotocky M; Ziegler DS; Koch A; Hernáiz Driever P; Witt O; Capper D; Sahm F; Jones DTW; van Tilburg CM
    Neuro Oncol; 2023 Nov; 25(11):2087-2097. PubMed ID: 37075810
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Early experience with targeted therapy as a first-line adjuvant treatment for pediatric low-grade glioma.
    Leclair NK; Lambert W; Roche K; Gillan E; Gell JJ; Lau CC; Wrubel G; Knopf J; Amin S; Anderson M; Martin JE; Bookland MJ; Hersh DS
    Neurosurg Focus; 2022 Dec; 53(6):E15. PubMed ID: 36455272
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. The clinical and molecular characteristics of progressive hypothalamic/optic pathway pilocytic astrocytoma.
    Li X; Moreira DC; Bag AK; Qaddoumi I; Acharya S; Chiang J
    Neuro Oncol; 2023 Apr; 25(4):750-760. PubMed ID: 36260562
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas.
    Misove A; Vicha A; Broz P; Vanova K; Sumerauer D; Stolova L; Sramkova L; Koblizek M; Zamecnik J; Kyncl M; Holubova Z; Liby P; Taborsky J; Benes V; Pernikova I; Jones DTW; Sill M; Stancokova T; Krskova L; Zapotocky M
    Acta Neuropathol Commun; 2022 Sep; 10(1):143. PubMed ID: 36163281
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling.
    Anastasaki C; Chatterjee J; Cobb O; Sanapala S; Scheaffer SM; De Andrade Costa A; Wilson AF; Kernan CM; Zafar AH; Ge X; Garbow JR; Rodriguez FJ; Gutmann DH
    Acta Neuropathol Commun; 2022 Aug; 10(1):120. PubMed ID: 35986378
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain tumor Models.
    Li F; Bondra KM; Ghilu S; Studebaker A; Liu Q; Michalek JE; Kogiso M; Li XN; Kalapurakal JA; James CD; Burma S; Kurmasheva RT; Houghton PJ
    Clin Cancer Res; 2022 Sep; 28(17):3836-3849. PubMed ID: 35797217
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Single-agent Bevacizumab in the treatment of Symptomatic Newly Diagnosed and Recurrent/Refractory Pediatric Cervicomedullary Brainstem Low-grade Gliomas: A Single Institutional Experience.
    Sridhar S; Paul MR; Yeh-Nayre L; Khanna PC; Elster J; Aristizabal P; Crawford JR
    J Pediatr Hematol Oncol; 2023 Jan; 45(1):e21-e25. PubMed ID: 35426868
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Molecular alterations in the integrated diagnosis of pediatric glial and glioneuronal tumors: A single center experience.
    Colli SL; Cardoso N; Massone CA; Cores M; García Lombardi M; De Matteo EN; Lorenzetti MA; Preciado MV
    PLoS One; 2022; 17(4):e0266466. PubMed ID: 35363819
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Oncogenic Fusions in Gliomas: An Institutional Experience.
    Polivka J; Svajdler M; Priban V; Mracek J; Kasik P; Martinek P; Ptakova N; Sharif Bagheri M; Shetti D; Pesta M; Potuznik P; Topolcan O
    Anticancer Res; 2022 Apr; 42(4):1933-1939. PubMed ID: 35347013
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The involvement of the MAPK pathway in pilocytic astrocytomas.
    Salles D; Santino SF; Ribeiro DA; Malinverni ACM; Stávale JN
    Pathol Res Pract; 2022 Apr; 232():153821. PubMed ID: 35231859
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. ADC Histogram Analysis of Pediatric Low-Grade Glioma Treated with Selumetinib: A Report from the Pediatric Brain tumor Consortium.
    Vajapeyam S; Brown D; Ziaei A; Wu S; Vezina G; Stern JS; Panigrahy A; Patay Z; Tamrazi B; Jones JY; Haque SS; Enterline DS; Cha S; Jones BV; Yeom KW; Onar-Thomas A; Dunkel IJ; Fouladi M; Fangusaro JR; Poussaint TY
    AJNR Am J Neuroradiol; 2022 Mar; 43(3):455-461. PubMed ID: 35210278
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Application of multiplex ligation-dependent probe amplification (MLPA) and low pass whole genome sequencing (LP-WGS) to the classification / characterisation of low grade glioneuronal tumours.
    Dyke J; Calapre L; Beasley A; Gray E; Allcock R; Bentel J
    Pathol Res Pract; 2022 Jan; 229():153724. PubMed ID: 34942511
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Gliomas in children and adolescents: investigation of molecular alterations with a potential prognostic and therapeutic impact.
    Cabral de Carvalho Corrêa D; Tesser-Gamba F; Dias Oliveira I; Saba da Silva N; Capellano AM; de Seixas Alves MT; Dastoli PA; Cavalheiro S; Caminada de Toledo SR
    J Cancer Res Clin Oncol; 2022 Jan; 148(1):107-119. PubMed ID: 34626238
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. [Pediatric Glioma].
    Terashima K; Ogiwara H
    No Shinkei Geka; 2021 May; 49(3):640-646. PubMed ID: 34092570
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Radiohistogenomics of pediatric low-grade neuroepithelial tumors.
    Bag AK; Chiang J; Patay Z
    Neuroradiology; 2021 Aug; 63(8):1185-1213. PubMed ID: 33779771
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. High frequency of disease progression in pediatric spinal cord low-grade glioma (LGG): management strategies and results from the german LGG study group.
    Perwein T; Benesch M; Kandels D; Pietsch T; Schmidt R; Quehenberger F; Bison B; Warmuth-Metz M; Timmermann B; Krauss J; Thomale UW; Kortmann RD; Driever PH; Gnekow AK
    Neuro Oncol; 2021 Jul; 23(7):1148-1162. PubMed ID: 33346834
    [TBL] [Abstract] [Full Text] [Related]  


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