BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND KRAS, C-K-RAS, 3845, P01116, NS3, KI-RAS, KRAS2, K-RAS4A, K-RAS2A, K-RAS4B, KRAS1, K-RAS2B, RASK2
637 results:

  • 1. Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
    Bellone S; Jeong K; Halle MK; Krakstad C; McNamara B; Greenman M; Mutlu L; Demirkiran C; Hartwich TMP; Yang-Hartwich Y; Zipponi M; Buza N; Hui P; Raspagliesi F; Lopez S; Paolini B; Milione M; Perrone E; Scambia G; Altwerger G; Ravaggi A; Bignotti E; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Schwartz PE; Quick CM; Angioli R; Terranova C; Zaidi S; Nandi S; Alexandrov LB; Siegel ER; Choi J; Schlessinger J; Santin AD
    Proc Natl Acad Sci U S A; 2024 Apr; 121(17):e2321898121. PubMed ID: 38625939
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Evolution of Testicular germ cell tumors in the Molecular Era With Histogenetic Implications.
    Kilic I; Acosta AM; Idrees MT
    Adv Anat Pathol; 2024 May; 31(3):206-214. PubMed ID: 38525515
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Cross-Species Comparison of the Pan-RAF Inhibitor LY3009120's Anti-tumor Effects in Equine, Canine, and Human Malignant Melanoma cell Lines.
    Gao Y; Packeiser EM; Wendt S; Sekora A; Cavalleri JV; Pratscher B; Alammar M; Hühns M; Brenig B; Junghanss C; Nolte I; Murua Escobar H
    Genes (Basel); 2024 Feb; 15(2):. PubMed ID: 38397192
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. FOXM1 promote the growth and metastasis of uveal melanoma cells by regulating CDK2 expression.
    Bai X; Li S; Luo Y
    Int Ophthalmol; 2024 Feb; 44(1):55. PubMed ID: 38342795
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. ARID2 mutations may relay a distinct subset of cutaneous melanoma patients with different outcomes.
    Akinjiyan FA; Nassief G; Phillipps J; Adeyelu T; Elliott A; Abdulla F; Zhou AY; Souroullas G; Kim KB; Vanderwalde A; Park SJ; Ansstas G
    Sci Rep; 2024 Feb; 14(1):3444. PubMed ID: 38341515
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. NRAS Mutant Dictates AHCYL1-Governed ER Calcium Homeostasis for Melanoma tumor Growth.
    Cai C; Tu J; Najarro J; Zhang R; Fan H; Zhang FQ; Li J; Xie Z; Su R; Dong L; Arellano N; Ciboddo M; Elf SE; Gao X; Chen J; Wu R
    Mol Cancer Res; 2024 Apr; 22(4):386-401. PubMed ID: 38294692
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Clinical utility of plasma cell-free DNA in pancreatic neuroendocrine neoplasms.
    Cowzer D; Shah RH; Chou JF; Kundra R; Punn S; Fiedler L; DeMore A; Capanu M; Berger MF; Reidy-Lagunes D; Raj N
    Endocr Relat Cancer; 2024 Apr; 31(4):. PubMed ID: 38252063
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Multiomics characterization of pyroptosis in the tumor microenvironment and therapeutic relevance in metastatic melanoma.
    Chen W; He Y; Zhou G; Chen X; Ye Y; Zhang G; Liu H
    BMC Med; 2024 Jan; 22(1):24. PubMed ID: 38229080
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. kras is a molecular determinant of platinum responsiveness in glioblastoma.
    Zuchegna C; Leone S; Romano A; Porcellini A; Messina S
    BMC Cancer; 2024 Jan; 24(1):77. PubMed ID: 38225605
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Antigen presentation deficiency, mesenchymal differentiation, and resistance to immunotherapy in the murine syngeneic CT2A tumor model.
    Iorgulescu JB; Ruthen N; Ahn R; Panagioti E; Gokhale PC; Neagu M; Speranza MC; Eschle BK; Soroko KM; Piranlioglu R; Datta M; Krishnan S; Yates KB; Baker GJ; Jain RK; Suvà ML; Neuberg D; White FM; Chiocca EA; Freeman GJ; Sharpe AH; Wu CJ; Reardon DA
    Front Immunol; 2023; 14():1297932. PubMed ID: 38213329
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Low incidence of BRAF and NRAS mutations in a population with a high incidence of melanoma.
    Neville G; Marzario B; Shilling D; Hand CK; Heffron C
    Virchows Arch; 2024 Mar; 484(3):475-479. PubMed ID: 38183457
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Metastatic Undifferentiated Melanoma Mimicking a Primary Bone tumor: A Potential Diagnostic Pitfall.
    Wills A; Dibbern M; Frierson HF; Raghavan SS
    Am J Dermatopathol; 2024 Mar; 46(3):170-172. PubMed ID: 38170737
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Real-World comprehensive genomic profiling data for diagnostic clarity in pulmonary Large-cell neuroendocrine carcinoma.
    Burns L; Tukachinsky H; Raskina K; Huang RSP; Schrock AB; Sands J; Kulke MH; Oxnard GR; Tapan U
    Lung Cancer; 2024 Feb; 188():107454. PubMed ID: 38159439
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. First-in-human study of naporafenib (LXH254) with or without spartalizumab in adult patients with advanced solid tumors harboring MAPK signaling pathway alterations.
    Janku F; Kim TM; Iyer G; Spreafico A; Elez E; de Jonge M; Yamamoto N; van der Wekken AJ; Ascierto PA; Maur M; Marmé F; Kiladjian JJ; Basu S; Baffert F; Buigues A; Chen C; Cooke V; Giorgetti E; Kim J; McCarthy F; Moschetta M; Dummer R
    Eur J Cancer; 2024 Jan; 196():113458. PubMed ID: 38039779
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. H3K27-altered diffuse midline gliomas with MAPK pathway alterations: Prognostic and therapeutic implications.
    Gestrich C; Grieco K; Lidov HG; Baird LC; Fehnel KP; Yeo KK; Meredith DM; Alexandrescu S
    J Neuropathol Exp Neurol; 2023 Dec; 83(1):30-35. PubMed ID: 38037182
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Gene expression profiling of pancreatic neuroendocrine carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm.
    Kinowaki Y; Fukumura Y; Kawade G; Sugita K; Kinowaki K; Akahoshi K; Kobayashi M; Ono H; Kudo A; Tanabe M; Akashi T; Ohashi K; Kurata M
    Gene; 2024 Jan; 893():147916. PubMed ID: 37866661
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Clinical impact of mixed pulmonary carcinoma and carcinoid: the driver from their mono-clonal origin.
    Graziano P; Parente P; Centra F; Milione M; Centonze G; Volante M; Cavazza A; Urbano D; Di Maggio G; Balsamo T; Di Micco C; Rossi G; Rossi A; Muscarella LA
    Virchows Arch; 2024 Jan; 484(1):37-46. PubMed ID: 37773451
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Glioma genetic profiles associated with electrophysiologic hyperexcitability.
    Tobochnik S; Dorotan MKC; Ghosh HS; Lapinskas E; Vogelzang J; Reardon DA; Ligon KL; Bi WL; Smirnakis SM; Lee JW
    Neuro Oncol; 2024 Feb; 26(2):323-334. PubMed ID: 37713468
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Primary mucosal melanomas of the urogenital tract: a clinical, pathological, and genetic nationwide survey of Danish patients 1990-2019.
    Znaider VK; Mikkelsen LH; Jensen CFS; Sønksen J; Heegaard S
    Scand J Urol; 2023 Aug; 58():52-59. PubMed ID: 37635444
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The Unmet Diagnostic and Treatment Needs in Large cell Neuroendocrine Carcinoma of the Lung.
    Buium C; Negru S; Ionescu DN; Dediu M
    Curr Oncol; 2023 Jul; 30(8):7218-7228. PubMed ID: 37623004
    [TBL] [Abstract] [Full Text] [Related]  


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