BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1 AND Prognosis
28 results:

  • 1. CD133 significance in glioblastoma development: in silico and in vitro study.
    Abdoli Shadbad M; Nejadi Orang F; Baradaran B
    Eur J Med Res; 2024 Mar; 29(1):154. PubMed ID: 38448914
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Network pharmacology-based strategy to investigate the effect and mechanism of α-solanine against glioma.
    Wang C; Liu X; Guo S
    BMC Complement Med Ther; 2023 Oct; 23(1):371. PubMed ID: 37865727
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Genomics and Epigenomics in the Molecular Biology of Melanoma-A Prerequisite for Biomarkers Studies.
    Zob DL; Augustin I; Caba L; Panzaru MC; Popa S; Popa AD; Florea L; Gorduza EV
    Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36614156
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Immune landscape-based machine-learning-assisted subclassification, prognosis, and immunotherapy prediction for glioblastoma.
    Li H; He J; Li M; Li K; Pu X; Guo Y
    Front Immunol; 2022; 13():1027631. PubMed ID: 36532035
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. LncRNA HOXA11-AS promotes glioma malignant phenotypes and reduces its sensitivity to ROS via Tpl2-mek1/2-ERK1/2 pathway.
    Wei C; Zhang X; Peng D; Zhang X; Guo H; Lu Y; Luo L; Wang B; Li Z; He Y; Du X; Zhang S; Liang H; Li S; Wang S; Han L; Zhang J
    Cell Death Dis; 2022 Nov; 13(11):942. PubMed ID: 36351895
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. FGFR2 loss sensitizes MYCN-amplified neuroblastoma CHP134 cells to CHK1 inhibitor-induced apoptosis.
    Ando K; Ohira M; Takada I; Cázares-Ordoñez V; Suenaga Y; Nagase H; Kobayashi S; Koshinaga T; Kamijo T; Makishima M; Wada S
    Cancer Sci; 2022 Feb; 113(2):587-596. PubMed ID: 34807483
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Merkel cell polyomavirus-negative Merkel cell carcinoma is associated with JAK-STAT and MEK-ERK pathway activation.
    Iwasaki T; Hayashi K; Matsushita M; Nonaka D; Kohashi K; Kuwamoto S; Umekita Y; Oda Y
    Cancer Sci; 2022 Jan; 113(1):251-260. PubMed ID: 34724284
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid tumors.
    Shahab S; Rubens J; Kaur H; Sweeney H; Eberhart CG; Raabe EH
    J Neuropathol Exp Neurol; 2020 Jul; 79(7):746-753. PubMed ID: 32472116
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. miRNA-183∼96∼182 regulates melanogenesis, cell proliferation and migration in B16 cells.
    Du B; Liu X; Khan A; Wan S; Guo X; Xue J; Fan R
    Acta Histochem; 2020 Apr; 122(3):151508. PubMed ID: 31980137
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uveal melanoma.
    Decaudin D; Frisch Dit Leitz E; Nemati F; Tarin M; Naguez A; Zerara M; Marande B; Vivet-Noguer R; Halilovic E; Fabre C; Jochemsen A; Roman-Roman S; Alsafadi S
    Eur J Cancer; 2020 Feb; 126():93-103. PubMed ID: 31927215
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.
    Nagler A; Vredevoogd DW; Alon M; Cheng PF; Trabish S; Kalaora S; Arafeh R; Goldin V; Levesque MP; Peeper DS; Samuels Y
    Pigment Cell Melanoma Res; 2020 Mar; 33(2):334-344. PubMed ID: 31549767
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. mek1/2 Inhibitors Unlock the Constrained Interferon Response in Macrophages Through IRF1 Signaling.
    Yang L; Ding JL
    Front Immunol; 2019; 10():2020. PubMed ID: 31507609
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Protein kinase C-α is upregulated by IMP1 in melanoma and is linked to poor survival.
    Mahapatra L; Andruska N; Mao C; Gruber SB; Johnson TM; Fullen DR; Raskin L; Shapiro DJ
    Melanoma Res; 2019 Oct; 29(5):539-543. PubMed ID: 30543563
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. MAP Kinase Pathways: Molecular Roads to Primary Acral Lentiginous Melanoma.
    Fernandes JD; Hsieh R; de Freitas LA; Brandao MA; Lourenço SV; Sangueza M; Nico MM
    Am J Dermatopathol; 2015 Dec; 37(12):892-7. PubMed ID: 26588333
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.
    Vieira GC; Chockalingam S; Melegh Z; Greenhough A; Malik S; Szemes M; Park JH; Kaidi A; Zhou L; Catchpoole D; Morgan R; Bates DO; Gabb PD; Malik K
    Oncotarget; 2015 Nov; 6(37):40053-67. PubMed ID: 26517508
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid.
    Friedman MD; Jeevan DS; Tobias M; Murali R; Jhanwar-Uniyal M
    Oncol Rep; 2013 Oct; 30(4):1645-50. PubMed ID: 23877261
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Selumetinib plus dacarbazine versus placebo plus dacarbazine as first-line treatment for BRAF-mutant metastatic melanoma: a phase 2 double-blind randomised study.
    Robert C; Dummer R; Gutzmer R; Lorigan P; Kim KB; Nyakas M; Arance A; Liszkay G; Schadendorf D; Cantarini M; Spencer S; Middleton MR
    Lancet Oncol; 2013 Jul; 14(8):733-40. PubMed ID: 23735514
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The CDKN2A and MAP kinase pathways: molecular roads to primary oral mucosal melanoma.
    Hsieh R; Nico MM; Coutinho-Camillo CM; Buim ME; Sangueza M; Lourenço SV
    Am J Dermatopathol; 2013 Apr; 35(2):167-75. PubMed ID: 23000904
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Selumetinib (AZD6244; ARRY-142886) in the treatment of metastatic melanoma.
    Patel SP; Kim KB
    Expert Opin Investig Drugs; 2012 Apr; 21(4):531-9. PubMed ID: 22394161
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Favourable prognosis in medulloblastoma with extensive nodularity is associated with mitogen-activated protein kinase upregulation.
    Jóźwiak J; Sontowska I; Bikowska B; Grajkowska W; Galus R; Roszkowski M
    Folia Neuropathol; 2011; 49(4):257-61. PubMed ID: 22212915
    [TBL] [Abstract] [Full Text] [Related]  


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