BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
29 results:

  • 1. TS-2021, a third-generation oncolytic adenovirus that carried Ki67 promoter, TGF-β2 5'UTR, and IL-15 against experimental glioblastoma.
    Wang J; Zhang J; Zhang Q; Zhang W; Zhang Q; Jin G; Liu F
    J Med Virol; 2024 Jan; 96(1):e29335. PubMed ID: 38149454
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs): a radiomic model to predict tumor grade.
    Chiti G; Grazzini G; Flammia F; Matteuzzi B; Tortoli P; Bettarini S; Pasqualini E; Granata V; Busoni S; Messserini L; Pradella S; Massi D; Miele V
    Radiol Med; 2022 Sep; 127(9):928-938. PubMed ID: 35917099
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the MKK/p38MAPK signaling pathway.
    Guo R; Lu SY; Ma JX; Wang QL; Zhang L; Tang LY; Shen Y; Shen CL; Wang JJ; Lu LM; Wang ZG; Zhang HX
    Hum Cell; 2022 Jul; 35(4):1071-1083. PubMed ID: 35416622
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Anti-Inflammatory, Antioxidant, Moisturizing, and Antimelanogenesis Effects of Quercetin 3-O-β-D-Glucuronide in Human Keratinocytes and Melanoma cells via Activation of NF-κB and AP-1 Pathways.
    Ha AT; Rahmawati L; You L; Hossain MA; Kim JH; Cho JY
    Int J Mol Sci; 2021 Dec; 23(1):. PubMed ID: 35008862
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Long noncoding RNA HNF1A-AS1 regulates proliferation and apoptosis of glioma through activation of the JNK signaling pathway via miR-363-3p/map2k4.
    Bi Y; Mao Y; Su Z; Du J; Ye L; Xu F
    J Cell Physiol; 2021 Feb; 236(2):1068-1082. PubMed ID: 32779194
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility.
    Dobson SJ; Anene A; Boyne JR; Mankouri J; Macdonald A; Whitehouse A
    Biochem J; 2020 Jul; 477(14):2721-2733. PubMed ID: 32639530
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression.
    Chen X; Hao A; Li X; Ye K; Zhao C; Yang H; Ma H; Hu L; Zhao Z; Hu L; Ye F; Sun Q; Zhang H; Wang H; Yao X; Fang Z
    Theranostics; 2020; 10(3):998-1015. PubMed ID: 31938047
    [No Abstract]    [Full Text] [Related]  

  • 8. Picroside II Protects SH-SY5Y cells From Autophagy and Apoptosis Following Oxygen Glucose Deprivation/Reoxygen Injury by Inhibiting JNK Signal Pathway.
    Wang T; Zhu L; Liu H; Yu G; Guo Y
    Anat Rec (Hoboken); 2019 Dec; 302(12):2245-2254. PubMed ID: 31251836
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. MKK7 transcription positively or negatively regulated by SP1 and KLF5 depends on HDAC4 activity in glioma.
    Wang Y; Xia Y; Hu K; Zeng M; Zhi C; Lai M; Wu L; Liu S; Zeng S; Huang Z; Ma S; Yuan Z
    Int J Cancer; 2019 Nov; 145(9):2496-2508. PubMed ID: 30963560
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. IDH1 Mutation Promotes tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation.
    Jiang B; Zhang J; Xia J; Zhao W; Wu Y; Shi M; Luo L; Zhou H; Chen A; Ma H; Zhao Q; Suleman M; Lin F; Zhou L; Wang J; Zhang Y; He Y; Li X; Hung LM; Mak TW; Li Q
    Cell Rep; 2017 Apr; 19(2):389-400. PubMed ID: 28402860
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells.
    He W; Wu Y; Tang X; Xia Y; He G; Min Z; Li C; Xiong S; Shi Z; Lu Y; Yuan Z
    Oncotarget; 2016 Feb; 7(6):6727-47. PubMed ID: 26734995
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule.
    Kitambi SS; Toledo EM; Usoskin D; Wee S; Harisankar A; Svensson R; Sigmundsson K; Kalderén C; Niklasson M; Kundu S; Aranda S; Westermark B; Uhrbom L; Andäng M; Damberg P; Nelander S; Arenas E; Artursson P; Walfridsson J; Forsberg Nilsson K; Hammarström LGJ; Ernfors P
    Cell; 2014 Apr; 157(2):313-328. PubMed ID: 24656405
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. p75 neurotrophin receptor and fenretinide-induced signaling in neuroblastoma.
    Ganeshan VR; Schor NF
    Cancer Chemother Pharmacol; 2014 Feb; 73(2):271-9. PubMed ID: 24253178
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Isoangustone A, a novel licorice compound, inhibits cell proliferation by targeting PI3K, mkk4, and MKK7 in human melanoma.
    Song NR; Lee E; Byun S; Kim JE; Mottamal M; Park JH; Lim SS; Bode AM; Lee HJ; Lee KW; Dong Z
    Cancer Prev Res (Phila); 2013 Dec; 6(12):1293-303. PubMed ID: 24104352
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin.
    Prickett TD; Zerlanko B; Gartner JJ; Parker SCJ; Dutton-Regester K; Lin JC; Teer JK; Wei X; Jiang J; Nisc Comparative Sequencing Program ; Chen G; Davies MA; Gershenwald JE; Robinson W; Robinson S; Hayward NK; Rosenberg SA; Margulies EH; Samuels Y
    J Invest Dermatol; 2014 Feb; 134(2):452-460. PubMed ID: 24008424
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Glucose 6-phosphate dehydrogenase deficiency enhances germ cell apoptosis and causes defective embryogenesis in Caenorhabditis elegans.
    Yang HC; Chen TL; Wu YH; Cheng KP; Lin YH; Cheng ML; Ho HY; Lo SJ; Chiu DT
    Cell Death Dis; 2013 May; 4(5):e616. PubMed ID: 23640458
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Ribotoxic stress sensitizes glioblastoma cells to death receptor induced apoptosis: requirements for c-Jun NH2-terminal kinase and Bim.
    Xia S; Li Y; Rosen EM; Laterra J
    Mol Cancer Res; 2007 Aug; 5(8):783-92. PubMed ID: 17699104
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Formyl peptide receptor like 1 differentially requires mitogen-activated protein kinases for the induction of glial fibrillary acidic protein and interleukin-1alpha in human U87 astrocytoma cells.
    Kam AY; Tse TT; Kwan DH; Wong YH
    Cell Signal; 2007 Oct; 19(10):2106-17. PubMed ID: 17643960
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.
    Costantini C; Rossi F; Formaggio E; Bernardoni R; Cecconi D; Della-Bianca V
    J Mol Neurosci; 2005; 25(2):141-56. PubMed ID: 15784962
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Identification of ASK1, mkk4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis.
    Kim SD; Moon CK; Eun SY; Ryu PD; Jo SA
    Biochem Biophys Res Commun; 2005 Mar; 328(1):326-34. PubMed ID: 15670787
    [TBL] [Abstract] [Full Text] [Related]  


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