BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Prognosis
96 results:

  • 1. The development of a custom RNA-sequencing panel for the identification of predictive and diagnostic biomarkers in glioma.
    Shirai Y; Ueno T; Kojima S; Ikeuchi H; Kitada R; Koyama T; Takahashi F; Takahashi K; Ichimura K; Yoshida A; Sugino H; Mano H; Narita Y; Takahashi M; Kohsaka S
    J Neurooncol; 2024 Mar; 167(1):75-88. PubMed ID: 38363490
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Competing Engagement of β-arrestin Isoforms Balances IGF1R/p53 Signaling and Controls Melanoma cell Chemotherapeutic Responsiveness.
    Cismas S; Pasca S; Crudden C; Trocoli Drakensjo I; Suleymanova N; Zhang S; Gebhard B; Song D; Neo S; Shibano T; Smith TJ; Calin GA; Girnita A; Girnita L
    Mol Cancer Res; 2023 Dec; 21(12):1288-1302. PubMed ID: 37584671
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. GSG2 facilitates the progression of human breast cancer through mdm2-mediated ubiquitination of E2F1.
    Tang Y; Dai G; Yang Y; Liu H
    J Transl Med; 2023 Aug; 21(1):523. PubMed ID: 37537694
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Molecular and Functional Heterogeneity of Primary Pancreatic Neuroendocrine tumors and Metastases.
    Guo Y; Tian C; Cheng Z; Chen R; Li Y; Su F; Shi Y; Tan H
    Neuroendocrinology; 2023; 113(9):943-956. PubMed ID: 37232011
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma.
    Huang R; Shen G; Ren Y; Zheng K; Wang J; Shi Y; Yin JC; Qin L; Zhang G; Zhao M; Su X; Li L; Wang F; Shao Y; Liu B; Zou Z
    J Transl Med; 2023 Feb; 21(1):78. PubMed ID: 36739402
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The miR-29 family members induce glioblastoma cell apoptosis by targeting cell division cycle 42 in a p53-dependent manner.
    Shi C; Luo W; Sun C; Yu L; Zhou X; Hua D; Jiang Z; Wang Q; Yu S
    Eur J Clin Invest; 2023 Jun; 53(6):e13964. PubMed ID: 36727260
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. LINC01426 aggravates the malignant progression of glioma through miR-661/mdm2 axis.
    Shu B; Gan H; Wang C; Cao C; Tong H; Liang D
    Brain Res Bull; 2022 Oct; 188():110-121. PubMed ID: 35772605
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. ATM germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications.
    El Jabbour T; Misyura M; Cowzer D; Zimmermann M; Rimkunas V; Marra A; Derakhshan F; Selenica P; Parilla M; Setton JS; Ceyhan-Birsoy O; Kemel Y; Catchings A; Ranganathan M; Ku GY; Janjigian YY; Zinda M; Koehler M; Stadler Z; Shia J; Reis-Filho JS; Mandelker D
    J Natl Cancer Inst; 2022 May; 114(5):761-770. PubMed ID: 35078243
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Clinicopathological and molecular genetic characteristics of adult IDH wild-type diffuse gliomas].
    Wang LM; Wang W; Liu L; Gao M; Yao YY; Zhang M; Xiong YL; Shao Y; Lu DH; Teng LH
    Zhonghua Bing Li Xue Za Zhi; 2021 Jul; 50(7):734-739. PubMed ID: 34405606
    [No Abstract]    [Full Text] [Related]  

  • 10. Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem cells.
    Smiley SB; Yun Y; Ayyagari P; Shannon HE; Pollok KE; Vannier MW; Das SK; Veronesi MC
    Pharm Res; 2021 Jun; 38(6):1067-1079. PubMed ID: 34100216
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Gene expression-based biomarkers designating glioblastomas resistant to multiple treatment strategies.
    Menyhárt O; Fekete JT; Győrffy B
    Carcinogenesis; 2021 Jun; 42(6):804-813. PubMed ID: 33754151
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The mdm2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth in models of neuroblastoma.
    Maser T; Zagorski J; Kelly S; Ostrander A; Goodyke A; Nagulapally A; Bond J; Park Y; Saulnier Sholler G
    Cancer Med; 2020 Nov; 9(21):8144-8158. PubMed ID: 33034426
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Targeting the p53-mdm2 pathway for neuroblastoma therapy: Rays of hope.
    Zafar A; Wang W; Liu G; Xian W; McKeon F; Zhou J; Zhang R
    Cancer Lett; 2021 Jan; 496():16-29. PubMed ID: 33007410
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Incorporating genomic signatures into surgical and medical decision-making for elderly glioblastoma patients.
    Ene CI; Cimino PJ; Fine HA; Holland EC
    Neurosurg Focus; 2020 Oct; 49(4):E11. PubMed ID: 33002863
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Inhibition of Retinoblastoma cell Growth by CEP1347 Through Activation of the P53 Pathway.
    Togashi K; Okada M; Suzuki S; Sanomachi T; Seino S; Yamamoto M; Yamashita H; Kitanaka C
    Anticancer Res; 2020 Sep; 40(9):4961-4968. PubMed ID: 32878784
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. p53 and mdm2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome.
    Lobo J; Alzamora MA; Guimarães R; Cantante M; Lopes P; Braga I; Maurício J; Jerónimo C; Henrique R
    Andrology; 2020 Sep; 8(5):1233-1242. PubMed ID: 32384200
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Ki-67 Index of 55% Distinguishes Two Groups of Bronchopulmonary Pure and Composite Large cell Neuroendocrine Carcinomas with Distinct prognosis.
    Milione M; Maisonneuve P; Grillo F; Mangogna A; Centonze G; Prinzi N; Pusceddu S; Garzone G; Cattaneo L; Busico A; Bossi P; Spaggiari P; Pellegrinelli A; Del Gobbo A; Ferrero S; Kankava K; Pruneri G; Rolli L; Roca E; Bercich L; Tironi A; Benvenuti MR; Gallazzi MS; Romano R; Berruti A; Pastorino U; Capella C
    Neuroendocrinology; 2021; 111(5):475-489. PubMed ID: 32365350
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Circ_0002770, acting as a competitive endogenous RNA, promotes proliferation and invasion by targeting miR-331-3p in melanoma.
    Qian P; Linbo L; Xiaomei Z; Hui P
    Cell Death Dis; 2020 Apr; 11(4):264. PubMed ID: 32327630
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Expression profiles and prognostic significance of WNT family members in glioma via bioinformatic analysis.
    Xu A; Yang H; Gao K; Zhan Z; Song Z; Huang T; Song Y
    Biosci Rep; 2020 Mar; 40(3):. PubMed ID: 32181818
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and mdm2 as a potential therapy in uveal melanoma.
    Decaudin D; Frisch Dit Leitz E; Nemati F; Tarin M; Naguez A; Zerara M; Marande B; Vivet-Noguer R; Halilovic E; Fabre C; Jochemsen A; Roman-Roman S; Alsafadi S
    Eur J Cancer; 2020 Feb; 126():93-103. PubMed ID: 31927215
    [TBL] [Abstract] [Full Text] [Related]  


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