BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND MYC, c-Myc, 4609, ENSG00000136997
2810 results:

  • 1. Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
    Bellone S; Jeong K; Halle MK; Krakstad C; McNamara B; Greenman M; Mutlu L; Demirkiran C; Hartwich TMP; Yang-Hartwich Y; Zipponi M; Buza N; Hui P; Raspagliesi F; Lopez S; Paolini B; Milione M; Perrone E; Scambia G; Altwerger G; Ravaggi A; Bignotti E; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Schwartz PE; Quick CM; Angioli R; Terranova C; Zaidi S; Nandi S; Alexandrov LB; Siegel ER; Choi J; Schlessinger J; Santin AD
    Proc Natl Acad Sci U S A; 2024 Apr; 121(17):e2321898121. PubMed ID: 38625939
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Mitotic gene regulation by the N-myc-WDR5-PDPK1 nexus.
    Streeter SA; Williams AG; Evans JR; Wang J; Guarnaccia AD; Florian AC; Al-Tobasei R; Liu Q; Tansey WP; Weissmiller AM
    BMC Genomics; 2024 Apr; 25(1):360. PubMed ID: 38605297
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. SIRT5 promote malignant advancement of chordoma by regulating the desuccinylation of c-myc.
    Jiang M; Huang Z; Chen L; Deng T; Liu J; Wu Y
    BMC Cancer; 2024 Mar; 24(1):386. PubMed ID: 38532359
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Patient-derived tumoroid models of pulmonary large-cell neuroendocrine carcinoma: a promising tool for personalized medicine and developing novel therapeutic strategies.
    Yokota E; Iwai M; Yukawa T; Naomoto Y; Haisa M; Monobe Y; Takigawa N; Fukazawa T; Yamatsuji T
    Cancer Lett; 2024 Apr; 588():216816. PubMed ID: 38499265
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor.
    Jablonowski CM; Quarni W; Singh S; Tan H; Bostanthirige DH; Jin H; Fang J; Chang TC; Finkelstein D; Cho JH; Hu D; Pagala V; Sakurada SM; Pruett-Miller SM; Wang R; Murphy A; Freeman K; Peng J; Davidoff AM; Wu G; Yang J
    Elife; 2024 Mar; 12():. PubMed ID: 38488852
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and myc that promotes group 3 medulloblastoma.
    Katsushima K; Joshi K; Yuan M; Romero B; Batish M; Stapleton S; Jallo G; Kolanthai E; Seal S; Saulnier O; Taylor MD; Wechsler-Reya RJ; Eberhart CG; Perera RJ
    Cell Rep; 2024 Mar; 43(3):113938. PubMed ID: 38460130
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Establishment of a transgene-free iPS cell line (SDCHi003-A) from a young patient bearing a NPRL2 mutation and suffering from Epilepsy.
    Su S; Zhao F; Zhang H; Liu Y; Li Z; Zhang H; Wang Y; Fang F; Liu Y
    Stem Cell Res; 2024 Apr; 76():103366. PubMed ID: 38430737
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. PRIM2: A Marker of myc-driven Hyper-proliferation, Disease Progression, tumor Aggressiveness and Poor Survival in Glioma Patients.
    Sun R; Shao X; Akter F; Zahid KR; Yao S; Ma L; Xu G
    Cancer Genomics Proteomics; 2024; 21(2):186-202. PubMed ID: 38423596
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. AF1q is a universal marker of neuroblastoma that sustains N-myc expression and drives tumorigenesis.
    Oskouian B; Lee JY; Asgharzadeh S; Khan R; Zhang M; Weisbrod JR; Choi YJ; Puri L; Aguilar AE; Zhao P; Saba JD
    Oncogene; 2024 Apr; 43(16):1203-1213. PubMed ID: 38413795
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. ICBP90, an epigenetic regulator, induces DKK3 promoter methylation, promotes glioma progression, and reduces sensitivity to cis-platinum.
    Cao Q; Wang X; Liu J; Dong Y; Wu X; Mi Y; Liu K; Zhang M; Shi Y; Fan R
    Exp Cell Res; 2024 Mar; 436(2):113976. PubMed ID: 38401687
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Development of a high-throughput screening platform to identify new therapeutic agents for Medulloblastoma Group 3.
    Fallon I; Hernando H; Almacellas-Rabaiget O; Marti-Fuster B; Spadoni C; Bigner DD; Méndez E
    SLAS Discov; 2024 Mar; 29(2):100147. PubMed ID: 38355016
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Approval of DFMO for high-risk neuroblastoma patients demonstrates a step of success to target myc pathway.
    Yang J
    Br J Cancer; 2024 Mar; 130(4):513-516. PubMed ID: 38316994
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. TRIM25 promotes glioblastoma cell growth and invasion via regulation of the PRMT1/c-myc pathway by targeting the splicing factor NONO.
    Chen Y; Xu X; Ding K; Tang T; Cai F; Zhang H; Chen Z; Qi Y; Fu Z; Zhu G; Dou Z; Xu J; Chen G; Wu Q; Ji J; Zhang J
    J Exp Clin Cancer Res; 2024 Feb; 43(1):39. PubMed ID: 38303029
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Generation of the human induced pluripotent stem cell line PUMCi005-A from a patient with Perrault syndrome.
    Wang YB; Lv YF; Zhang Y; Wang W
    Stem Cell Res; 2024 Mar; 75():103318. PubMed ID: 38295749
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-myc-UHRF1 interactions.
    Xue Z; Zhang Y; Zhao R; Liu X; Grützmann K; Klink B; Zhang X; Wang S; Zhao W; Sun Y; Han M; Wang X; Hu Y; Liu X; Yang N; Qiu C; Li W; Huang B; Li X; Bjerkvig R; Wang J; Zhou W
    J Exp Clin Cancer Res; 2024 Jan; 43(1):25. PubMed ID: 38246990
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas.
    Liu S; Chai T; Garcia-Marques F; Yin Q; Hsu EC; Shen M; Shaw Toland AM; Bermudez A; Hartono AB; Massey CF; Lee CS; Zheng L; Baron M; Denning CJ; Aslan M; Nguyen HM; Nolley R; Zoubeidi A; Das M; Kunder CA; Howitt BE; Soh HT; Weissman IL; Liss MA; Chin AI; Brooks JD; Corey E; Pitteri SJ; Huang J; Stoyanova T
    Cell Rep Med; 2024 Feb; 5(2):101381. PubMed ID: 38244540
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. An in-silico analysis reveals further evidence of an aggressive subset of lung carcinoids sharing molecular features of high-grade neuroendocrine neoplasms.
    Pelosi G; Melocchi V; Dama E; Hofman P; De Luca M; Albini A; Gemelli M; Ricotta R; Papotti M; La Rosa S; Uccella S; Harari S; Sonzogni A; Asiedu MK; Wigle DA; Bianchi F
    Exp Mol Pathol; 2024 Feb; 135():104882. PubMed ID: 38237798
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Ribogenesis boosts controlled by HEATR1-myc interplay promote transition into brain tumour growth.
    Diaz LR; Gil-Ranedo J; Jaworek KJ; Nsek N; Marques JP; Costa E; Hilton DA; Bieluczyk H; Warrington O; Hanemann CO; Futschik ME; Bossing T; Barros CS
    EMBO Rep; 2024 Jan; 25(1):168-197. PubMed ID: 38225354
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Treatment-related Neuroendocrine Prostate Carcinoma-Diagnostic and Molecular Correlates.
    Gopalan A
    Adv Anat Pathol; 2024 Mar; 31(2):70-79. PubMed ID: 38223983
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 myc-amplified Medulloblastoma.
    Coulter DW; Chhonker YS; Kumar D; Kesherwani V; Aldhafiri WN; McIntyre EM; Alexander G; Ray S; Joshi SS; Li R; Murry DJ; Chaturvedi NK
    J Exp Clin Cancer Res; 2024 Jan; 43(1):18. PubMed ID: 38200580
    [TBL] [Abstract] [Full Text] [Related]  


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