BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND NDRG1, NDR1, 10397, ENSG00000104419, Q92597, RIT42, CMT4D, TARG1, HMSNL, GC4, RTP, TDD5, PROXY1, NMSL, CAP43
57 results:

  • 1. Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness.
    Monti M; Benerini Gatta L; Bugatti M; Pezzali I; Picinoli S; Manfredi M; Lavazza A; Vanella VV; De Giorgis V; Zanatta L; Missale F; Lonardi S; Zanetti B; Bozzoni G; Cadei M; Abate A; Vergani B; Balzarini P; Battocchio S; Facco C; Turri-Zanoni M; Castelnuovo P; Nicolai P; Fonsatti E; Leone BE; Marengo E; Sigala S; Ronca R; Perego M; Lombardi D; Vermi W
    J Transl Med; 2024 Jan; 22(1):35. PubMed ID: 38191367
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.
    Frank D; Patnana PK; Vorwerk J; Mao L; Gopal LM; Jung N; Hennig T; Ruhnke L; Frenz JM; Kuppusamy M; Autry R; Wei L; Sun K; Mohammed Ahmed HM; Künstner A; Busch H; Müller H; Hutter S; Hoermann G; Liu L; Xie X; Al-Matary Y; Nimmagadda SC; Cano FC; Heuser M; Thol F; Göhring G; Steinemann D; Thomale J; Leitner T; Fischer A; Rad R; Röllig C; Altmann H; Kunadt D; Berdel WE; Hüve J; Neumann F; Klingauf J; Calderon V; Opalka B; Dührsen U; Rosenbauer F; Dugas M; Varghese J; Reinhardt HC; von Bubnoff N; Möröy T; Lenz G; Batcha AMN; Giorgi M; Selvam M; Wang E; McWeeney SK; Tyner JW; Stölzel F; Mann M; Jayavelu AK; Khandanpour C
    Blood; 2023 Dec; 142(25):2175-2191. PubMed ID: 37756525
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Explore the impact of hypoxia-related genes (HRGs) in Cutaneous melanoma.
    Ke G; Cheng N; Sun H; Meng X; Xu L
    BMC Med Genomics; 2023 Jul; 16(1):160. PubMed ID: 37422626
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Clinical feasibility of a commercially available MRI-only method for radiotherapy treatment planning of the brain.
    Ranta I; Wright P; Suilamo S; Kemppainen R; Schubert G; Kapanen M; Keyriläinen J
    J Appl Clin Med Phys; 2023 Sep; 24(9):e14044. PubMed ID: 37345212
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The Myc Family and the Metastasis Suppressor ndrg1: Targeting Key Molecular Interactions with Innovative Therapeutics.
    Deng Z; Richardson DR
    Pharmacol Rev; 2023 Sep; 75(5):1007-1035. PubMed ID: 37280098
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells.
    Nguekeu-Zebaze L; Hanini N; Noll A; Wadier N; Amé JC; Roegel L; Dantzer F
    Sci Rep; 2022 Sep; 12(1):15534. PubMed ID: 36109561
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. N-myc Downstream-Regulated Gene 1 (ndrg1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM).
    Zhang X; Chen Q; Li Y; Chen H; Jiang Q; Hu Q
    Biomed Res Int; 2022; 2022():3233004. PubMed ID: 35813230
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Iron-Chelation Treatment by Novel Thiosemicarbazone Targets Major Signaling Pathways in Neuroblastoma.
    Macsek P; Skoda J; Krchniakova M; Neradil J; Veselska R
    Int J Mol Sci; 2021 Dec; 23(1):. PubMed ID: 35008802
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of glioma by regulating PTEN/PI3K/AKT signaling via binding to N‑myc downstream regulated gene 1 promoter.
    Zhang J; Yang Y; Dong Y; Liu C
    Int J Mol Med; 2022 Feb; 49(2):. PubMed ID: 34913078
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Targeting radiation-tolerant persister cells as a strategy for inhibiting radioresistance and recurrence in glioblastoma.
    Gu J; Mu N; Jia B; Guo Q; Pan L; Zhu M; Zhang W; Zhang K; Li W; Li M; Wei L; Xue X; Zhang Y; Zhang W
    Neuro Oncol; 2022 Jul; 24(7):1056-1070. PubMed ID: 34905060
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Innovative therapies for neuroblastoma: The surprisingly potent role of iron chelation in up-regulating metastasis and tumor suppressors and down-regulating the key oncogene, N-myc.
    Wijesinghe TP; Dharmasivam M; Dai CC; Richardson DR
    Pharmacol Res; 2021 Nov; 173():105889. PubMed ID: 34536548
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Nuclear Dbf2-related Kinase 1 functions as tumor suppressor in glioblastoma by phosphorylation of Yes-associated protein.
    Chen B; Liu B; Yu T; Han YF; Wu C; Wang ZY
    Chin Med J (Engl); 2021 Aug; 134(17):2054-2065. PubMed ID: 34343153
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The Influence of ndrg1 Single Nucleotide Polymorphisms on Glioma Risk and Prognosis in Chinese Han Population.
    Yang Y; Cheng Y; Yang L; Shi G; Chen P; Li L; Fang H; Chen C; Jin T
    Cell Mol Neurobiol; 2022 Aug; 42(6):1949-1964. PubMed ID: 33709284
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma.
    Song LB; Luan JC; Zhang QJ; Chen L; Wang HY; Cao XC; Song NH; Lu Y
    J Immunol Res; 2021; 2021():6686284. PubMed ID: 33688507
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Usefulness of an immunohistochemical score in advanced pancreatic neuroendocrine tumors treated with CAPTEM or everolimus.
    Viúdez A; Crespo G; Gómez Dorronsoro ML; Arozarena I; Marín-Méndez JJ; Custodio A; Benavent M; Goñi S; García-Paredes B; Hernando J; Durantez M; Alonso V; Riesco MDC; López C; Jiménez-Fonseca P; San Vicente BL; González-Borja I; Sevilla I; Hernández-Garcia I; Carmona-Bayonas A; Capdevila J; Pérez-Sanz J; García-Carbonero R; Pérez-Ricarte L; Llanos M; Vera R; De Jesús Acosta A
    Pancreatology; 2021 Jan; 21(1):215-223. PubMed ID: 33358592
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. SNAP reverses temozolomide resistance in human glioblastoma multiforme cells through down-regulation of MGMT.
    Tsai CK; Huang LC; Wu YP; Kan IY; Hueng DY
    FASEB J; 2019 Dec; 33(12):14171-14184. PubMed ID: 31725331
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Bidirectional Regulation between ndrg1 and GSK3β Controls tumor Growth and Is Targeted by Differentiation Inducing Factor-1 in Glioblastoma.
    Ito H; Watari K; Shibata T; Miyamoto T; Murakami Y; Nakahara Y; Izumi H; Wakimoto H; Kuwano M; Abe T; Ono M
    Cancer Res; 2020 Jan; 80(2):234-248. PubMed ID: 31723002
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Merkel cell Polyomavirus Downregulates N-myc Downstream-Regulated Gene 1, Leading to cellular Proliferation and Migration.
    Gupta P; Shahzad N; Harold A; Shuda M; Venuti A; Romero-Medina MC; Pacini L; Brault L; Robitaille A; Taverniti V; Hernandez-Vargas H; Durand G; Le Calvez-Kelm F; Gheit T; Accardi R; Tommasino M
    J Virol; 2020 Jan; 94(3):. PubMed ID: 31694959
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. DNA-PKcs is activated under nutrient starvation and activates Akt, MST1, FoxO3a, and ndr1.
    Shiga S; Murata Y; Hashimoto T; Urushihara Y; Fujishima Y; Kudo K; Sonohara Y; Kurusu M; Takeda K; Jingu K; Hosoi Y
    Biochem Biophys Res Commun; 2020 Jan; 521(3):668-673. PubMed ID: 31679687
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Hypoxic Gene Signature of Primary and Metastatic Melanoma cell Lines: Focusing on HIF-1β and NDRG-1.
    Ercin ME; Bozdoğan Ö; Çavuşoğlu T; Bozdoğan N; Atasoy P; Koçak M
    Balkan Med J; 2019 Dec; 37(1):15-23. PubMed ID: 31594284
    [TBL] [Abstract] [Full Text] [Related]  


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