BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND PDGFRA, MGC74795, 5156, ENSG00000134853, PDGFR2, CD140A, Rhe-PDGFRA, CD140a, P16234
343 results:

  • 1. Pediatric-type high-grade gliomas with pdgfra amplification in adult patients with Li-Fraumeni syndrome: clinical and molecular characterization of three cases.
    Kibe Y; Ohka F; Aoki K; Yamaguchi J; Motomura K; Ito E; Takeuchi K; Nagata Y; Ito S; Mizutani N; Shiba Y; Maeda S; Nishikawa T; Shimizu H; Saito R
    Acta Neuropathol Commun; 2024 Apr; 12(1):57. PubMed ID: 38605367
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm.
    Wang L; Wang H; D'Angelo F; Curtin L; Sereduk CP; Leon G; Singleton KW; Urcuyo J; Hawkins-Daarud A; Jackson PR; Krishna C; Zimmerman RS; Patra DP; Bendok BR; Smith KA; Nakaji P; Donev K; Baxter LC; Mrugała MM; Ceccarelli M; Iavarone A; Swanson KR; Tran NL; Hu LS; Li J
    PLoS One; 2024; 19(4):e0299267. PubMed ID: 38568950
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clinical and molecular study of radiation-induced gliomas.
    Trkova K; Sumerauer D; Bubenikova A; Krskova L; Vicha A; Koblizek M; Zamecnik J; Jurasek B; Kyncl M; Malinova B; Ondrova B; Jones DTW; Sill M; Strnadova M; Stolova L; Misove A; Benes V; Zapotocky M
    Sci Rep; 2024 Feb; 14(1):3118. PubMed ID: 38326438
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression.
    Appin CL; Hong C; Suwala AK; Hilz S; Mathur R; Solomon DA; Smirnov IV; Stevers NO; Shai A; Wang A; Berger MS; Chang SM; Phillips JJ; Costello JF
    Neuro Oncol; 2024 Apr; 26(4):640-652. PubMed ID: 38141254
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
    Hadad S; Gupta R; Oberheim Bush NA; Taylor JW; Villanueva-Meyer JE; Young JS; Wu J; Ravindranathan A; Zhang Y; Warrier G; McCoy L; Shai A; Pekmezci M; Perry A; Bollen AW; Phillips JJ; Braunstein SE; Raleigh DR; Theodosopoulos P; Aghi MK; Chang EF; Hervey-Jumper SL; Costello JF; de Groot J; Butowski NA; Clarke JL; Chang SM; Berger MS; Molinaro AM; Solomon DA
    Acta Neuropathol; 2023 Dec; 147(1):3. PubMed ID: 38079020
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Prognostic model for assessing the human glioma cell malignancy grade based on MDM2, MELK, SOX2, CDK4, DR5 and OCT4 gene expression.
    Tyagunova EE; Drozd SF; Kalennik OV; Samoylenkova NS; Savchenko EA; Danilov GV; Pavlova GV
    Zh Vopr Neirokhir Im N N Burdenko; 2023; 87(6):43-51. PubMed ID: 38054226
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Optimal combination of MYCN differential gene and cellular senescence gene predicts adverse outcomes in patients with neuroblastoma.
    Tan J; Wang C; Jin Y; Xia Y; Gong B; Zhao Q
    Front Immunol; 2023; 14():1309138. PubMed ID: 38035110
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genetic alterations that deregulate RB and pdgfra signaling pathways drive tumor progression in IDH2-mutant astrocytoma.
    Tateishi K; Miyake Y; Nakamura T; Iwashita H; Hayashi T; Oshima A; Honma H; Hayashi H; Sugino K; Kato M; Satomi K; Fujii S; Komori T; Yamamoto T; Cahill DP; Wakimoto H
    Acta Neuropathol Commun; 2023 Nov; 11(1):186. PubMed ID: 38012788
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
    Rautajoki KJ; Jaatinen S; Hartewig A; Tiihonen AM; Annala M; Salonen I; Valkonen M; Simola V; Vuorinen EM; Kivinen A; Rauhala MJ; Nurminen R; Maass KK; Lahtela SL; Jukkola A; Yli-Harja O; Helén P; Pajtler KW; Ruusuvuori P; Haapasalo J; Zhang W; Haapasalo H; Nykter M
    Acta Neuropathol Commun; 2023 Nov; 11(1):176. PubMed ID: 37932833
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. pdgfra, KIT, and KDR Gene Amplification in Glioblastoma: Heterogeneity and Clinical Significance.
    Carlotto BS; Trevisan P; Provenzi VO; Soares FP; Rosa RFM; Varella-Garcia M; Zen PRG
    Neuromolecular Med; 2023 Sep; 25(3):441-450. PubMed ID: 37610648
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Сell clusters isolation in glioblastomas and their functional and molecular characterization using new morphometric approaches.
    Nikitin PV; Musina GR; Fayzullin AL; Bakulina AA; Nikolaev VN; Mikhailov VP; Werkenbark L; Kjelin M; Usachev DY; Timashev PS
    Comput Biol Med; 2023 Sep; 164():107322. PubMed ID: 37582322
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. [Expression and significance of INSM1 and SOX11 in pancreatic neuroendocrine tumor and solid pseudopapillary neoplasm].
    Cao Z; Cen HB; Zhao JH; Mei J; Qin LZ; Liao W; Ao QL
    Beijing Da Xue Xue Bao Yi Xue Ban; 2023 Aug; 55(4):575-581. PubMed ID: 37534634
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. ROS1 Alterations as a Potential Driver of Gliomas in Infant, Pediatric, and Adult Patients.
    Meredith DM; Cooley LD; Dubuc A; Morrissette J; Sussman RT; Nasrallah MP; Rathbun P; Yap KL; Wadhwani N; Bao L; Wolff DJ; Ida C; Sukhanova M; Horbinski C; Jennings LJ; Farooqi M; Gener M; Ginn K; Kam KL; Sasaki K; Kanagal-Shamanna R; Alexandrescu S; Brat D; Lu X
    Mod Pathol; 2023 Nov; 36(11):100294. PubMed ID: 37532182
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4.
    Williams EA; Brastianos PK; Wakimoto H; Zolal A; Filbin MG; Cahill DP; Santagata S; Juratli TA
    Acta Neuropathol; 2023 Sep; 146(3):515-525. PubMed ID: 37524847
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Modeling epigenetic lesions that cause gliomas.
    Rahme GJ; Javed NM; Puorro KL; Xin S; Hovestadt V; Johnstone SE; Bernstein BE
    Cell; 2023 Aug; 186(17):3674-3685.e14. PubMed ID: 37494934
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high-grade gliomas.
    Reuss DE; Downing SM; Camacho CV; Wang YD; Piro RM; Herold-Mende C; Wang ZQ; Hofmann TG; Sahm F; von Deimling A; McKinnon PJ; Frappart PO
    Neuropathol Appl Neurobiol; 2023 Aug; 49(4):e12915. PubMed ID: 37296499
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Diffuse Pediatric-type High-grade Glioma Arising in an Ovarian Mature Cystic Teratoma.
    Elmuti L; Amundson J; Oberman E; Kamat A; Sedig L; Lastra RR; Aldape K; Quezado M; Pratt DW; Cimino PJ; Abdullaev Z; Pytel P; Applebaum MA; Bennett JA
    Int J Gynecol Pathol; 2024 Jan; 43(1):90-96. PubMed ID: 37046379
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Oncogenic long noncoding RNA LINC02283 enhances PDGF receptor A-mediated signaling and drives glioblastoma tumorigenesis.
    Goenka A; Song X; Tiek D; Iglesia RP; Lu M; Zeng C; Horbinski C; Zhang W; Hu B; Cheng SY
    Neuro Oncol; 2023 Sep; 25(9):1592-1604. PubMed ID: 36988488
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. H3 G34-mutant high-grade gliomas: integrated clinical, imaging and pathological characterisation of a single-centre case series.
    Lavrador JP; Reisz Z; Sibtain N; Rajwani K; Baig Mirza A; Vergani F; Gullan R; Bhangoo R; Ashkan K; Bleil C; Zebian B; Clark B; Laxton R; King A; Bodi I; Al-Saraj S
    Acta Neurochir (Wien); 2023 Jun; 165(6):1615-1633. PubMed ID: 36929449
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma.
    Walentynowicz KA; Engelhardt D; Cristea S; Yadav S; Onubogu U; Salatino R; Maerken M; Vincentelli C; Jhaveri A; Geisberg J; McDonald TO; Michor F; Janiszewska M
    Cell Rep; 2023 Mar; 42(3):112235. PubMed ID: 36920905
    [TBL] [Abstract] [Full Text] [Related]  


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