Terms: = Germ cell tumor AND PDGFRB, JTK12, 5159, P09619, ENSG00000113721, PDGF-R-beta, PDGFR1, CD140B, PDGFR, CD140b AND Treatment
179 results:
1. Regorafenib and glioblastoma: a literature review of preclinical studies, molecular mechanisms and clinical effectiveness.
Mongiardi MP; Pallini R; D'Alessandris QG; Levi A; Falchetti ML
Expert Rev Mol Med; 2024 Apr; 26():e5. PubMed ID: 38563164
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2. Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres.
Pallocca M; Molineris I; Berrino E; Marcozzi B; Betti M; Levati L; D'Atri S; Menin C; Madonna G; Ghiorzo P; Bulgarelli J; Ferraresi V; Venesio T; Rodolfo M; Rivoltini L; Lanfrancone L; Ascierto PA; Mazzarella L; Pelicci PG; De Maria R; Ciliberto G; Medico E; Russo G
J Transl Med; 2024 Jan; 22(1):29. PubMed ID: 38184610
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3. Anlotinib alone or in combination with bevacizumab in the treatment of recurrent high-grade glioma: a prospective single-arm, open-label phase II trial.
Zhao S; Zhang M; Zhang Q; Wu J; Dai H
BMC Cancer; 2024 Jan; 24(1):6. PubMed ID: 38166698
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4. A study on molecular mechanism of Xihuang pill in the treatment of glioblastoma based on network pharmacology and validation in vitro and in vivo.
Xu HB; Chen XZ; Zhu SY; Xue F; Zhang YB
J Ethnopharmacol; 2024 Apr; 323():117675. PubMed ID: 38159819
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5. The effects of ALK5 inhibition and simultaneous inhibition or activation of HIF-1α in melanoma tumor growth and angiogenesis.
Zarin B; Nedaeinia R; Laher I; Manian M; Javanmard SH
Tumour Biol; 2023; 45(1):111-126. PubMed ID: 37927290
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6. Unveiling Novel Avenues in mTOR-Targeted Therapeutics: Advancements in Glioblastoma treatment.
Singh S; Barik D; Lawrie K; Mohapatra I; Prasad S; Naqvi AR; Singh A; Singh G
Int J Mol Sci; 2023 Oct; 24(19):. PubMed ID: 37834408
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7. tumor Treating Fields Alter the Kinomic Landscape in Glioblastoma Revealing Therapeutic Vulnerabilities.
Jones AB; Schanel TL; Rigsby MR; Griguer CE; McFarland BC; Anderson JC; Willey CD; Hjelmeland AB
Cells; 2023 Aug; 12(17):. PubMed ID: 37681903
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8. Unraveling the signaling mechanism behind astrocytoma and possible therapeutics strategies: A comprehensive review.
Nahar Metu CL; Sutihar SK; Sohel M; Zohora F; Hasan A; Miah MT; Rani Kar T; Hossain MA; Rahman MH
Cancer Rep (Hoboken); 2023 Oct; 6(10):e1889. PubMed ID: 37675821
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9. Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting.
Gimple RC; Zhang G; Wang S; Huang T; Lee J; Taori S; Lv D; Dixit D; Halbert ME; Morton AR; Kidwell RL; Dong Z; Prager BC; Kim LJ; Qiu Z; Zhao L; Xie Q; Wu Q; Agnihotri S; Rich JN
JCI Insight; 2023 Mar; 8(6):. PubMed ID: 36795488
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10. Discovery of a CSF-1R inhibitor and PET tracer for imaging of microglia and macrophages in the brain.
van der Wildt B; Klockow JL; Miao Z; Reyes ST; Park JH; Shen B; Chin FT
Nucl Med Biol; 2022; 114-115():99-107. PubMed ID: 36371938
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11. Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a pdgfr inhibitor.
Arunachalam S; Szlachta K; Brady SW; Ma X; Ju B; Shaner B; Mulder HL; Easton J; Raphael BJ; Myers M; Tinkle C; Allen SJ; Orr BA; Wetmore CJ; Baker SJ; Zhang J
Acta Neuropathol Commun; 2022 May; 10(1):80. PubMed ID: 35642016
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12. PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38
Lane R; Cilibrasi C; Chen J; Shah K; Messuti E; Mazarakis NK; Stebbing J; Critchley G; Song E; Simon T; Giamas G
Oncogene; 2022 May; 41(19):2749-2763. PubMed ID: 35393545
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13. Targeted therapy with anlotinib for a H3K27M mutation diffuse midline glioma patient with pdgfr-α mutation: a case report.
Wang Q; Niu W; Pan H
Acta Neurochir (Wien); 2022 Aug; 164(8):2063-2066. PubMed ID: 34812950
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14. Anlotinib in Locally Advanced or Metastatic Medullary Thyroid Carcinoma: A Randomized, Double-Blind Phase IIB Trial.
Li D; Chi Y; Chen X; Ge M; Zhang Y; Guo Z; Wang J; Chen J; Zhang J; Cheng Y; Li Z; Liu H; Qin J; Zhu J; Cheng R; Xu Z; Zheng X; Tang P; Gao M
Clin Cancer Res; 2021 Jul; 27(13):3567-3575. PubMed ID: 33832949
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15. Pediatric high-grade glioma: aberrant epigenetics and kinase signaling define emerging therapeutic opportunities.
Sun Y; Bailey CP; Sadighi Z; Zaky W; Chandra J
J Neurooncol; 2020 Oct; 150(1):17-26. PubMed ID: 32504402
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16. Efficient Suppression of NRAS-Driven Melanoma by Co-Inhibition of ERK1/2 and ERK5 MAPK Pathways.
Adam C; Fusi L; Weiss N; Goller SG; Meder K; Frings VG; Kneitz H; Goebeler M; Houben R; Schrama D; Schmidt M
J Invest Dermatol; 2020 Dec; 140(12):2455-2465.e10. PubMed ID: 32376279
[TBL] [Abstract] [Full Text] [Related]
17. Small molecule tyrosine kinase inhibitors in glioblastoma.
Kim G; Ko YT
Arch Pharm Res; 2020 Apr; 43(4):385-394. PubMed ID: 32239429
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18. Gene expression profile and bioinformatics analysis revealed key molecular characteristics of chordoma-before and after TNF- a treatment.
Xu G; Liu C; Liang T; Zhang Z; Jiang J; Chen J; Xue J; Zeng H; Lu Z; Zhan X
Medicine (Baltimore); 2020 Jan; 99(3):e18790. PubMed ID: 32011476
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19. Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma.
Tiago M; Capparelli C; Erkes DA; Purwin TJ; Heilman SA; Berger AC; Davies MA; Aplin AE
Br J Cancer; 2020 Mar; 122(6):789-800. PubMed ID: 31932756
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20. Novel
Hassan M; Butler E; Wilson R; Roy A; Zheng Y; Liem P; Rakheja D; Pavlick D; Young LL; Rosenzweig M; Erlich R; Ali SM; Leavey PJ; Parsons DW; Skapek SX; Laetsch TW
Cold Spring Harb Mol Case Stud; 2019 Oct; 5(5):. PubMed ID: 31645346
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