BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Clinical Outcome
35 results:

  • 1. MrgprF acts as a tumor suppressor in cutaneous melanoma by restraining pi3k/Akt signaling.
    Shen Q; Han Y; Wu K; He Y; Jiang X; Liu P; Xia C; Xiong Q; Liu R; Chen Q; Zhang Y; Zhao S; Yang C; Chen Y
    Signal Transduct Target Ther; 2022 May; 7(1):147. PubMed ID: 35504869
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Silencing FYVE, RhoGEF, and PH domain containing 1 (FGD1) suppresses melanoma progression by inhibiting pi3k/AKT signaling pathway.
    Niu Z; Li Y; Xu Y; Jiang W; Tao R; Chen Y; Han Y
    Bioengineered; 2021 Dec; 12(2):12193-12205. PubMed ID: 34783295
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
    Suwala AK; Stichel D; Schrimpf D; Kloor M; Wefers AK; Reinhardt A; Maas SLN; Kratz CP; Schweizer L; Hasselblatt M; Snuderl M; Abedalthagafi MSJ; Abdullaev Z; Monoranu CM; Bergmann M; Pekrun A; Freyschlag C; Aronica E; Kramm CM; Hinz F; Sievers P; Korshunov A; Kool M; Pfister SM; Sturm D; Jones DTW; Wick W; Unterberg A; Hartmann C; Dodgshun A; Tabori U; Wesseling P; Sahm F; von Deimling A; Reuss DE
    Acta Neuropathol; 2021 Jan; 141(1):85-100. PubMed ID: 33216206
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
    Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
    Cancer Lett; 2020 Jan; 469():195-206. PubMed ID: 31672491
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells.
    Matteoni S; Abbruzzese C; Matarrese P; De Luca G; Mileo AM; Miccadei S; Schenone S; Musumeci F; Haas TL; Sette G; Carapella CM; Amato R; Perrotti N; Signore M; Paggi MG
    J Exp Clin Cancer Res; 2019 May; 38(1):202. PubMed ID: 31101126
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Distinct Molecular Profiles and Immunotherapy Treatment outcomes of V600E and V600K
    Pires da Silva I; Wang KYX; Wilmott JS; Holst J; Carlino MS; Park JJ; Quek C; Wongchenko M; Yan Y; Mann G; Johnson DB; McQuade JL; Rai R; Kefford RF; Rizos H; Scolyer RA; Yang JYH; Long GV; Menzies AM
    Clin Cancer Res; 2019 Feb; 25(4):1272-1279. PubMed ID: 30630828
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inhibition of pi3k signalling increases the efficiency of radiotherapy in glioblastoma cells.
    Hasslacher S; Schneele L; Stroh S; Langhans J; Zeiler K; Kattner P; Karpel-Massler G; Siegelin MD; Schneider M; Zhou S; Grunert M; Halatsch ME; Nonnenmacher L; Debatin KM; Westhoff MA
    Int J Oncol; 2018 Nov; 53(5):1881-1896. PubMed ID: 30132519
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genomic Characterization of Testicular germ cell tumors Relapsing After Chemotherapy.
    Necchi A; Bratslavsky G; Corona RJ; Chung JH; Millis SZ; Elvin JA; Vergilio JA; Suh J; Ramkissoon S; Severson E; Daniel S; Killian JK; Ali SM; Schrock AB; Reddy P; Miller VA; Welsh A; Gay LM; Ross JS
    Eur Urol Focus; 2020 Jan; 6(1):122-130. PubMed ID: 30025711
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Autophagy-induced KDR/VEGFR-2 activation promotes the formation of vasculogenic mimicry by glioma stem cells.
    Wu HB; Yang S; Weng HY; Chen Q; Zhao XL; Fu WJ; Niu Q; Ping YF; Wang JM; Zhang X; Yao XH; Bian XW
    Autophagy; 2017 Sep; 13(9):1528-1542. PubMed ID: 28812437
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Continuous Petri Nets and microRNA Analysis in Melanoma.
    Russo G; Pennisi M; Boscarino R; Pappalardo F
    IEEE/ACM Trans Comput Biol Bioinform; 2018; 15(5):1492-1499. PubMed ID: 28767374
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via pi3k/Akt signaling in glioma.
    Song Y; Zheng S; Wang J; Long H; Fang L; Wang G; Li Z; Que T; Liu Y; Li Y; Zhang X; Fang W; Qi S
    Oncotarget; 2017 Jun; 8(26):41947-41962. PubMed ID: 28410212
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Targeted next generation sequencing of mucosal melanomas identifies frequent NF1 and RAS mutations.
    Cosgarea I; Ugurel S; Sucker A; Livingstone E; Zimmer L; Ziemer M; Utikal J; Mohr P; Pfeiffer C; Pföhler C; Hillen U; Horn S; Schadendorf D; Griewank KG; Roesch A
    Oncotarget; 2017 Jun; 8(25):40683-40692. PubMed ID: 28380455
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional pi3k inhibition.
    Craveiro RB; Ehrhardt M; Velz J; Olschewski M; Goetz B; Pietsch T; Dilloo D
    Oncotarget; 2017 Jul; 8(29):46915-46927. PubMed ID: 28159923
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. AKT/GSK3β Signaling in Glioblastoma.
    Majewska E; Szeliga M
    Neurochem Res; 2017 Mar; 42(3):918-924. PubMed ID: 27568206
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells.
    Morell C; Bort A; Vara D; Ramos-Torres A; Rodríguez-Henche N; Díaz-Laviada I
    Prostate Cancer Prostatic Dis; 2016 Sep; 19(3):248-57. PubMed ID: 27324222
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Phase II study of PX-866 in recurrent glioblastoma.
    Pitz MW; Eisenhauer EA; MacNeil MV; Thiessen B; Easaw JC; Macdonald DR; Eisenstat DD; Kakumanu AS; Salim M; Chalchal H; Squire J; Tsao MS; Kamel-Reid S; Banerji S; Tu D; Powers J; Hausman DF; Mason WP
    Neuro Oncol; 2015 Sep; 17(9):1270-4. PubMed ID: 25605819
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Macrophage migration inhibitory factor engages pi3k/Akt signalling and is a prognostic factor in metastatic melanoma.
    Oliveira CS; de Bock CE; Molloy TJ; Sadeqzadeh E; Geng XY; Hersey P; Zhang XD; Thorne RF
    BMC Cancer; 2014 Aug; 14():630. PubMed ID: 25168062
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. CD4 T cells require ICOS-mediated pi3k signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy.
    Chen H; Fu T; Suh WK; Tsavachidou D; Wen S; Gao J; Ng Tang D; He Q; Sun J; Sharma P
    Cancer Immunol Res; 2014 Feb; 2(2):167-76. PubMed ID: 24778280
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. TRIM24 promotes glioma progression and enhances chemoresistance through activation of the pi3k/Akt signaling pathway.
    Zhang LH; Yin AA; Cheng JX; Huang HY; Li XM; Zhang YQ; Han N; Zhang X
    Oncogene; 2015 Jan; 34(5):600-10. PubMed ID: 24469053
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas.
    Suenaga Y; Islam SM; Alagu J; Kaneko Y; Kato M; Tanaka Y; Kawana H; Hossain S; Matsumoto D; Yamamoto M; Shoji W; Itami M; Shibata T; Nakamura Y; Ohira M; Haraguchi S; Takatori A; Nakagawara A
    PLoS Genet; 2014 Jan; 10(1):e1003996. PubMed ID: 24391509
    [TBL] [Abstract] [Full Text] [Related]  


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