BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
35 results:

  • 1. Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases.
    Peng WY; Abere B; Shi H; Toland S; Smithgall TE; Moore PS; Chang Y
    Proc Natl Acad Sci U S A; 2023 Dec; 120(51):e2316467120. PubMed ID: 38079542
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Pyroptosis: a novel signature to predict prognosis and immunotherapy response in gliomas.
    He G; Chen Z; Zhuo S; Tang J; Hao W; Yang K; Yang C
    Hum Cell; 2022 Nov; 35(6):1976-1992. PubMed ID: 36129672
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Role of PLCγ1 in the modulation of cell migration and cell invasion in glioblastoma.
    Marvi MV; Mongiorgi S; Ramazzotti G; Follo MY; Billi AM; Zoli M; Mazzatenta D; Morandi L; Asioli S; Papa V; McCubrey JA; Suh PG; Manzoli L; Cocco L; Ratti S
    Adv Biol Regul; 2022 Jan; 83():100838. PubMed ID: 34819252
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Phospholipase Cγ1 (plcg1) overexpression is associated with tumor growth and poor survival in IDH wild-type lower-grade gliomas in adult patients.
    Li T; Yang Z; Li H; Zhu J; Wang Y; Tang Q; Shi Z
    Lab Invest; 2022 Feb; 102(2):143-153. PubMed ID: 34697421
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Proteogenomic and metabolomic characterization of human glioblastoma.
    Wang LB; Karpova A; Gritsenko MA; Kyle JE; Cao S; Li Y; Rykunov D; Colaprico A; Rothstein JH; Hong R; Stathias V; Cornwell M; Petralia F; Wu Y; Reva B; Krug K; Pugliese P; Kawaler E; Olsen LK; Liang WW; Song X; Dou Y; Wendl MC; Caravan W; Liu W; Cui Zhou D; Ji J; Tsai CF; Petyuk VA; Moon J; Ma W; Chu RK; Weitz KK; Moore RJ; Monroe ME; Zhao R; Yang X; Yoo S; Krek A; Demopoulos A; Zhu H; Wyczalkowski MA; McMichael JF; Henderson BL; Lindgren CM; Boekweg H; Lu S; Baral J; Yao L; Stratton KG; Bramer LM; Zink E; Couvillion SP; Bloodsworth KJ; Satpathy S; Sieh W; Boca SM; Schürer S; Chen F; Wiznerowicz M; Ketchum KA; Boja ES; Kinsinger CR; Robles AI; Hiltke T; Thiagarajan M; Nesvizhskii AI; Zhang B; Mani DR; Ceccarelli M; Chen XS; Cottingham SL; Li QK; Kim AH; Fenyö D; Ruggles KV; Rodriguez H; Mesri M; Payne SH; Resnick AC; Wang P; Smith RD; Iavarone A; Chheda MG; Barnholtz-Sloan JS; Rodland KD; Liu T; Ding L;
    Cancer Cell; 2021 Apr; 39(4):509-528.e20. PubMed ID: 33577785
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Concomitant
    Rodriguez R; Fournier B; Cordeiro DJ; Winter S; Izawa K; Martin E; Boutboul D; Lenoir C; Fraitag S; Kracker S; Watts TH; Picard C; Bruneau J; Callebaut I; Fischer A; Neven B; Latour S
    J Exp Med; 2019 Dec; 216(12):2800-2818. PubMed ID: 31537641
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Prevalence of Small Intestine Carcinoid tumors: A US Population-Based Study 2012-2017.
    Abou Saleh M; Mansoor E; Anindo M; Isenberg G
    Dig Dis Sci; 2019 May; 64(5):1328-1334. PubMed ID: 30519851
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Cost Estimate of Immune-Related Adverse Reactions Associated with Innovative Treatments of Metastatic Melanoma.
    Mennini FS; Bini C; Marcellusi A; Del Vecchio M
    Clin Drug Investig; 2018 Oct; 38(10):967-976. PubMed ID: 30143953
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer cell Invasion.
    Raimondi C; Calleja V; Ferro R; Fantin A; Riley AM; Potter BV; Brennan CH; Maffucci T; Larijani B; Falasca M
    Sci Rep; 2016 May; 6():26142. PubMed ID: 27199173
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes.
    Lanciotti A; Brignone MS; Visentin S; De Nuccio C; Catacuzzeno L; Mallozzi C; Petrini S; Caramia M; Veroni C; Minnone G; Bernardo A; Franciolini F; Pessia M; Bertini E; Petrucci TC; Ambrosini E
    Hum Mol Genet; 2016 Apr; 25(8):1543-58. PubMed ID: 26908604
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. FGFR1 Induces Glioblastoma Radioresistance through the PLCγ/Hif1α Pathway.
    Gouazé-Andersson V; Delmas C; Taurand M; Martinez-Gala J; Evrard S; Mazoyer S; Toulas C; Cohen-Jonathan-Moyal E
    Cancer Res; 2016 May; 76(10):3036-44. PubMed ID: 26896280
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance.
    Palmer DC; Guittard GC; Franco Z; Crompton JG; Eil RL; Patel SJ; Ji Y; Van Panhuys N; Klebanoff CA; Sukumar M; Clever D; Chichura A; Roychoudhuri R; Varma R; Wang E; Gattinoni L; Marincola FM; Balagopalan L; Samelson LE; Restifo NP
    J Exp Med; 2015 Nov; 212(12):2095-113. PubMed ID: 26527801
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Activating MET kinase rearrangements in melanoma and Spitz tumours.
    Yeh I; Botton T; Talevich E; Shain AH; Sparatta AJ; de la Fouchardiere A; Mully TW; North JP; Garrido MC; Gagnon A; Vemula SS; McCalmont TH; LeBoit PE; Bastian BC
    Nat Commun; 2015 May; 6():7174. PubMed ID: 26013381
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.
    Mathew LK; Huangyang P; Mucaj V; Lee SS; Skuli N; Eisinger-Mathason TS; Biju K; Li B; Venneti S; Lal P; Lathia JD; Rich JN; Keith B; Simon MC
    Sci Signal; 2015 May; 8(375):ra42. PubMed ID: 25943352
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib.
    Zhao Q; Kretschmer N; Bauer R; Efferth T
    Int J Cancer; 2015 Sep; 137(6):1446-56. PubMed ID: 25688715
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma Multiforme.
    Waugh MG
    Mol Neurobiol; 2016 Jan; 53(1):621-630. PubMed ID: 25502460
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. CXCR4 pathway associated with family history of melanoma.
    Li WQ; Han J; Widlund HR; Correll M; Wang YE; Quackenbush J; Mihm MC; Canales AL; Wu S; Golub T; Hoshida Y; Hunter DJ; Murphy G; Kupper TS; Qureshi AA
    Cancer Causes Control; 2014 Jan; 25(1):125-32. PubMed ID: 24158781
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.
    Yang W; Xia Y; Cao Y; Zheng Y; Bu W; Zhang L; You MJ; Koh MY; Cote G; Aldape K; Li Y; Verma IM; Chiao PJ; Lu Z
    Mol Cell; 2012 Dec; 48(5):771-84. PubMed ID: 23123196
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival.
    Serão NV; Delfino KR; Southey BR; Beever JE; Rodriguez-Zas SL
    BMC Med Genomics; 2011 Jun; 4():49. PubMed ID: 21649900
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Identification of phospholipase C gamma1 as a protein tyrosine phosphatase mu substrate that regulates cell migration.
    Phillips-Mason PJ; Kaur H; Burden-Gulley SM; Craig SE; Brady-Kalnay SM
    J Cell Biochem; 2011 Jan; 112(1):39-48. PubMed ID: 20506511
    [TBL] [Abstract] [Full Text] [Related]  


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