BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND PPM1D, Wip1, 8493, ENSG00000170836, O15297, WIP1, PP2C-DELTA AND Treatment
15 results:

  • 1. Association of Nonmelanoma Skin Cancers, Melanoma, and Merkel cell Carcinoma with Dermatologic Medications: A Case-Control Pharmacovigilance Study of the FDA Adverse Events Reporting System.
    Jedlowski PM
    Dermatology; 2023; 239(5):694-699. PubMed ID: 37054693
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Computer-aided detection and segmentation of malignant melanoma lesions on whole-body
    Dirks I; Keyaerts M; Neyns B; Vandemeulebroucke J
    Comput Methods Programs Biomed; 2022 Jun; 221():106902. PubMed ID: 35636357
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. TP53 wild-type/ppm1d mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.
    Xu C; Liu H; Pirozzi CJ; Chen LH; Greer PK; Diplas BH; Zhang L; Waitkus MS; He Y; Yan H
    Acta Neuropathol Commun; 2021 Nov; 9(1):178. PubMed ID: 34732238
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Targeting Mutant ppm1d Sensitizes Diffuse Intrinsic Pontine Glioma cells to the PARP Inhibitor Olaparib.
    Wang Z; Xu C; Diplas BH; Moure CJ; Chen CJ; Chen LH; Du C; Zhu H; Greer PK; Zhang L; He Y; Waitkus MS; Yan H
    Mol Cancer Res; 2020 Jul; 18(7):968-980. PubMed ID: 32229503
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. ppm1d mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
    Fons NR; Sundaram RK; Breuer GA; Peng S; McLean RL; Kalathil AN; Schmidt MS; Carvalho DM; Mackay A; Jones C; Carcaboso ÁM; Nazarian J; Berens ME; Brenner C; Bindra RS
    Nat Commun; 2019 Aug; 10(1):3790. PubMed ID: 31439867
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Inhibition of mutant ppm1d enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma.
    Akamandisa MP; Nie K; Nahta R; Hambardzumyan D; Castellino RC
    Neuro Oncol; 2019 Jun; 21(6):786-799. PubMed ID: 30852603
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inhibition of protein phosphatase ppm1d enhances retinoic acid-induced differentiation in human embryonic carcinoma cell line.
    Ogasawara S; Chuman Y; Michiba T; Kamada R; Imagawa T; Sakaguchi K
    J Biochem; 2019 Jun; 165(6):471-477. PubMed ID: 30576481
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Targeting negative regulation of p53 by MDM2 and wip1 as a therapeutic strategy in cutaneous melanoma.
    Wu CE; Esfandiari A; Ho YH; Wang N; Mahdi AK; Aptullahoglu E; Lovat P; Lunec J
    Br J Cancer; 2018 Feb; 118(4):495-508. PubMed ID: 29235570
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Combination of lentivirus-mediated silencing of ppm1d and temozolomide chemotherapy eradicates malignant glioma through cell apoptosis and cell cycle arrest.
    Wang P; Ye JA; Hou CX; Zhou D; Zhan SQ
    Oncol Rep; 2016 Nov; 36(5):2544-2552. PubMed ID: 27633132
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. wip1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.
    Wen J; Lee J; Malhotra A; Nahta R; Arnold AR; Buss MC; Brown BD; Maier C; Kenney AM; Remke M; Ramaswamy V; Taylor MD; Castellino RC
    Oncogene; 2016 Oct; 35(42):5552-5564. PubMed ID: 27086929
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Analysis of genes involved in response to doxorubicin and a GD2 ganglioside-specific 14G2a monoclonal antibody in IMR-32 human neuroblastoma cells.
    Horwacik I; Durbas M; Boratyn E; Sawicka A; Węgrzyn P; Krzanik S; Górka A; Drożniak J; Augustyniak E; Kowalczyk A; Rokita H
    Acta Biochim Pol; 2015; 62(3):423-33. PubMed ID: 26284262
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. wip1 phosphatase as a potential therapeutic target in neuroblastoma.
    Richter M; Dayaram T; Gilmartin AG; Ganji G; Pemmasani SK; Van Der Key H; Shohet JM; Donehower LA; Kumar R
    PLoS One; 2015; 10(2):e0115635. PubMed ID: 25658463
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. HDM2 promotes wip1-mediated medulloblastoma growth.
    Buss MC; Read TA; Schniederjan MJ; Gandhi K; Castellino RC
    Neuro Oncol; 2012 Apr; 14(4):440-58. PubMed ID: 22379189
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. p53 Regulates LIF expression in human medulloblastoma cells.
    Baxter EW; Milner J
    J Neurooncol; 2010 May; 97(3):373-82. PubMed ID: 19907922
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma.
    Mendrzyk F; Radlwimmer B; Joos S; Kokocinski F; Benner A; Stange DE; Neben K; Fiegler H; Carter NP; Reifenberger G; Korshunov A; Lichter P
    J Clin Oncol; 2005 Dec; 23(34):8853-62. PubMed ID: 16314645
    [TBL] [Abstract] [Full Text] [Related]  


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