BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Germ cell tumor AND PREX2, 6230420N16Rik, DEPDC2, 80243, ENSG00000046889, FLJ12987, DEP_2, P-REX2
14 results:

  • 1. Methylation and mutation of the inhibin‑α gene in human melanoma cells and regulation of PTEN expression and AKT/PI3K signaling by a demethylating agent.
    Ko H; Ahn HJ; Kim YI
    Oncol Rep; 2022 Feb; 47(2):. PubMed ID: 34958114
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein Facilitates Glioma Progression via Akt and Stat3 Signaling.
    Shang J; Li Y; Yin G; Li Z; Jiang L; Bai Q
    J Mol Neurosci; 2021 Aug; 71(8):1674-1682. PubMed ID: 34322848
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clinicopathological and genomic features in patients with head and neck neuroendocrine carcinoma.
    Ohmoto A; Sato Y; Asaka R; Fukuda N; Wang X; Urasaki T; Hayashi N; Sato Y; Nakano K; Yunokawa M; Ono M; Tomomatsu J; Toshiyasu T; Mitani H; Takeuchi K; Mori S; Takahashi S
    Mod Pathol; 2021 Nov; 34(11):1979-1989. PubMed ID: 34247193
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The Molecular Landscape of Primary Acral Melanoma: A Multicenter Study of the Italian Melanoma Intergroup (IMI).
    Elefanti L; Zamuner C; Del Fiore P; Stagni C; Pellegrini S; Dall'Olmo L; Fabozzi A; Senetta R; Ribero S; Salmaso R; Mocellin S; Bassetto F; Cavallin F; Tosi AL; Galuppini F; Dei Tos AP; Menin C; Cappellesso R
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33917086
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Integrative Exome and Transcriptome Analysis of Conjunctival Melanoma and Its Potential Application for Personalized Therapy.
    Demirci H; Demirci FY; Ciftci S; Elner VM; Wu YM; Ning Y; Chinnaiyan A; Robinson DR
    JAMA Ophthalmol; 2019 Dec; 137(12):1444-1448. PubMed ID: 31647501
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Towards Personalized Medicine in Melanoma: Implementation of a Clinical Next-Generation Sequencing Panel.
    de Unamuno Bustos B; Murria Estal R; Pérez Simó G; de Juan Jimenez I; Escutia Muñoz B; Rodríguez Serna M; Alegre de Miquel V; Llavador Ros M; Ballester Sánchez R; Nagore Enguídanos E; Palanca Suela S; Botella Estrada R
    Sci Rep; 2017 Mar; 7(1):495. PubMed ID: 28356599
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Replication Study: Melanoma genome sequencing reveals frequent
    Horrigan SK; Courville P; Sampey D; Zhou F; Cai S;
    Elife; 2017 Jan; 6():. PubMed ID: 28100394
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Melanoma mystery.
    Davis RJ
    Elife; 2017 Jan; 6():. PubMed ID: 28100393
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Interplay between prex2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
    Lissanu Deribe Y
    Small GTPases; 2016 Jul; 7(3):178-85. PubMed ID: 27111337
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Truncating prex2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
    Lissanu Deribe Y; Shi Y; Rai K; Nezi L; Amin SB; Wu CC; Akdemir KC; Mahdavi M; Peng Q; Chang QE; Hornigold K; Arold ST; Welch HC; Garraway LA; Chin L
    Proc Natl Acad Sci U S A; 2016 Mar; 113(9):E1296-305. PubMed ID: 26884185
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Registered report: Melanoma genome sequencing reveals frequent prex2 mutations.
    Chroscinski D; Sampey D; Hewitt A;
    Elife; 2014 Dec; 3():. PubMed ID: 25490935
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Oncogenes in melanoma: an update.
    Kunz M
    Eur J Cell Biol; 2014; 93(1-2):1-10. PubMed ID: 24468268
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. [Melanoma: from molecular studies to the treatment breakthrough].
    Imianitov EN
    Arkh Patol; 2013; 75(5):63-72. PubMed ID: 24341237
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Melanoma genome sequencing reveals frequent prex2 mutations.
    Berger MF; Hodis E; Heffernan TP; Deribe YL; Lawrence MS; Protopopov A; Ivanova E; Watson IR; Nickerson E; Ghosh P; Zhang H; Zeid R; Ren X; Cibulskis K; Sivachenko AY; Wagle N; Sucker A; Sougnez C; Onofrio R; Ambrogio L; Auclair D; Fennell T; Carter SL; Drier Y; Stojanov P; Singer MA; Voet D; Jing R; Saksena G; Barretina J; Ramos AH; Pugh TJ; Stransky N; Parkin M; Winckler W; Mahan S; Ardlie K; Baldwin J; Wargo J; Schadendorf D; Meyerson M; Gabriel SB; Golub TR; Wagner SN; Lander ES; Getz G; Chin L; Garraway LA
    Nature; 2012 May; 485(7399):502-6. PubMed ID: 22622578
    [TBL] [Abstract] [Full Text] [Related]  


    of 1.